Saturated fat ingestion stimulates proatherogenic inflammation in polycystic ovary syndrome Article Swipe
Related Concepts
Polycystic ovary
Ingestion
Internal medicine
Endocrinology
Inflammation
Obesity
Medicine
Ovary
Insulin resistance
Frank González
,
Robert V. Considine
,
Ola A. Abdelhadi
,
Jiaping Xue
,
Anthony J. Acton
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1152/ajpendo.00213.2021
· OA: W3206395141
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1152/ajpendo.00213.2021
· OA: W3206395141
This paper demonstrates that in polycystic ovary syndrome (PCOS), ingestion of saturated fat triggers a molecular pathway of inflammation known to drive atherogenesis. This effect is independent of obesity as it occurs in lean women with PCOS and not in lean ovulatory control subjects. Furthermore, the combined effects of PCOS and obesity are greater compared with obesity alone.
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