Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study Article Swipe
Joyce Y. Wu
,
Monisha Goyal
,
Jurriaan M. Peters
,
Darcy A. Krueger
,
Mustafa Şahin
,
Hope Northrup
,
Kit Sing Au
,
Sarah O’Kelley
,
Marian E. Williams
,
Deborah A. Pearson
,
Ellen Hanson
,
Anna W. Byars
,
Jessica Krefting
,
Mark Beasley
,
Gary Cutter
,
Nita A. Limdi
,
E. Martina Bebin
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1111/epi.16379
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1111/epi.16379
Objective To determine if routine electroencephalography (EEG) in seizure‐naive infants with tuberous sclerosis complex (TSC) can predict epilepsy and subsequent neurocognitive outcomes. Methods Forty infants 7 months of age or younger and meeting the genetic or clinical diagnostic criteria for tuberous sclerosis were enrolled. Exclusion criteria included prior history of seizures or treatment with antiseizure medications. At each visit, seizure history and 1‐hour awake and asleep video‐EEG, standardized across all sites, were obtained until 2 years of age. Developmental assessments (Mullen and Vineland‐II) were completed at 6, 12, and 24 months of age. Results Of 40 infants enrolled (mean age of 82.4 days), 32 completed the study. Two were lost to follow‐up and six were treated with antiepileptic drugs (AEDs) due to electrographic seizures and/or interictal epileptiform discharges (IEDs) on their EEG studies prior to the onset of clinical seizures. Seventeen of the 32 remaining children developed epilepsy at a mean age of 7.5 months (standard deviation [SD] = 4.4). Generalized/focal slowing, hypsarrhythmia, and generalized/focal attenuation were not predictive for the development of clinical seizures. Presence of IEDs had a 77.3% positive predictive value and absence a 70% negative predictive value for developing seizures by 2 years of age. IEDs preceded clinical seizure onset by 3.6 months (mean). Developmental testing showed significant decline, only in infants with ongoing seizures, but not infants who never developed seizures or whose seizures came under control. Significance IEDs identify impending epilepsy in the majority (77%) of seizure‐naive infants with TSC. The use of a 1‐hour awake and asleep EEG can be used as a biomarker for ongoing epileptogenesis in most, but not all, infants with TSC. Persistent seizures, but not history of interictal epileptiform activity or history of well‐controlled seizures, correlated with low scores on the Vineland and Mullen tests at 2 years of age.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/epi.16379
- OA Status
- hybrid
- Cited By
- 61
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2982862638
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2982862638Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1111/epi.16379Digital Object Identifier
- Title
-
Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational studyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-11-05Full publication date if available
- Authors
-
Joyce Y. Wu, Monisha Goyal, Jurriaan M. Peters, Darcy A. Krueger, Mustafa Şahin, Hope Northrup, Kit Sing Au, Sarah O’Kelley, Marian E. Williams, Deborah A. Pearson, Ellen Hanson, Anna W. Byars, Jessica Krefting, Mark Beasley, Gary Cutter, Nita A. Limdi, E. Martina BebinList of authors in order
- Landing page
-
https://doi.org/10.1111/epi.16379Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1111/epi.16379Direct OA link when available
- Concepts
-
Observational study, Scalp, Epilepsy, Electroencephalography, Audiology, Medicine, Psychology, Pediatrics, Psychiatry, Surgery, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
61Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 7, 2024: 9, 2023: 10, 2022: 7, 2021: 15Per-year citation counts (last 5 years)
- References (count)
-
15Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2982862638 |
|---|---|
| doi | https://doi.org/10.1111/epi.16379 |
| ids.doi | https://doi.org/10.1111/epi.16379 |
| ids.mag | 2982862638 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/31691264 |
| ids.openalex | https://openalex.org/W2982862638 |
| fwci | 6.26292142 |
| mesh[0].qualifier_ui | Q000502 |
| mesh[0].descriptor_ui | D000200 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | physiology |
| mesh[0].descriptor_name | Action Potentials |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D015331 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Cohort Studies |
| mesh[2].qualifier_ui | Q000379 |
| mesh[2].descriptor_ui | D004569 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | methods |
| mesh[2].descriptor_name | Electroencephalography |
| mesh[3].qualifier_ui | Q000639 |
| mesh[3].descriptor_ui | D004569 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | trends |
| mesh[3].descriptor_name | Electroencephalography |
| mesh[4].qualifier_ui | Q000175 |
| mesh[4].descriptor_ui | D004827 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | diagnosis |
| mesh[4].descriptor_name | Epilepsy |
| mesh[5].qualifier_ui | Q000503 |
| mesh[5].descriptor_ui | D004827 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | physiopathology |
| mesh[5].descriptor_name | Epilepsy |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D005260 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Female |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D005500 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Follow-Up Studies |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D006801 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Humans |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D007223 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Infant |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D008137 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Longitudinal Studies |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D008297 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Male |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D011237 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Predictive Value of Tests |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D011446 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Prospective Studies |
| mesh[14].qualifier_ui | Q000502 |
| mesh[14].descriptor_ui | D012535 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | physiology |
| mesh[14].descriptor_name | Scalp |
| mesh[15].qualifier_ui | Q000175 |
| mesh[15].descriptor_ui | D014402 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | diagnosis |
| mesh[15].descriptor_name | Tuberous Sclerosis |
| mesh[16].qualifier_ui | Q000503 |
| mesh[16].descriptor_ui | D014402 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | physiopathology |
| mesh[16].descriptor_name | Tuberous Sclerosis |
| mesh[17].qualifier_ui | Q000502 |
| mesh[17].descriptor_ui | D000200 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | physiology |
| mesh[17].descriptor_name | Action Potentials |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D015331 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Cohort Studies |
| mesh[19].qualifier_ui | Q000379 |
| mesh[19].descriptor_ui | D004569 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | methods |
| mesh[19].descriptor_name | Electroencephalography |
| mesh[20].qualifier_ui | Q000639 |
| mesh[20].descriptor_ui | D004569 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | trends |
| mesh[20].descriptor_name | Electroencephalography |
| mesh[21].qualifier_ui | Q000175 |
| mesh[21].descriptor_ui | D004827 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | diagnosis |
| mesh[21].descriptor_name | Epilepsy |
| mesh[22].qualifier_ui | Q000503 |
| mesh[22].descriptor_ui | D004827 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | physiopathology |
| mesh[22].descriptor_name | Epilepsy |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D005260 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Female |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D005500 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Follow-Up Studies |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D006801 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Humans |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D007223 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Infant |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D008137 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Longitudinal Studies |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D008297 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Male |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D011237 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Predictive Value of Tests |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D011446 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Prospective Studies |
| mesh[31].qualifier_ui | Q000502 |
| mesh[31].descriptor_ui | D012535 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | physiology |
| mesh[31].descriptor_name | Scalp |
| mesh[32].qualifier_ui | Q000175 |
| mesh[32].descriptor_ui | D014402 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | diagnosis |
| mesh[32].descriptor_name | Tuberous Sclerosis |
| mesh[33].qualifier_ui | Q000503 |
| mesh[33].descriptor_ui | D014402 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | physiopathology |
| mesh[33].descriptor_name | Tuberous Sclerosis |
| type | article |
| title | Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study |
| awards[0].id | https://openalex.org/G7541882276 |
| awards[0].funder_id | https://openalex.org/F4320337472 |
| awards[0].display_name | |
| awards[0].funder_award_id | UL1TR001881 |
| awards[0].funder_display_name | National Center for Advancing Translational Sciences |
| awards[1].id | https://openalex.org/G1643264655 |
| awards[1].funder_id | https://openalex.org/F4320337472 |
| awards[1].display_name | |
| awards[1].funder_award_id | 8UL1TR000077 |
| awards[1].funder_display_name | National Center for Advancing Translational Sciences |
| biblio.issue | 12 |
| biblio.volume | 60 |
| biblio.last_page | 2436 |
| biblio.first_page | 2428 |
| topics[0].id | https://openalex.org/T12049 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2737 |
| topics[0].subfield.display_name | Physiology |
| topics[0].display_name | Tuberous Sclerosis Complex Research |
| topics[1].id | https://openalex.org/T12552 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9861999750137329 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2735 |
| topics[1].subfield.display_name | Pediatrics, Perinatology and Child Health |
| topics[1].display_name | Fetal and Pediatric Neurological Disorders |
| topics[2].id | https://openalex.org/T11163 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9749000072479248 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2739 |
| topics[2].subfield.display_name | Public Health, Environmental and Occupational Health |
| topics[2].display_name | Organ Donation and Transplantation |
| funders[0].id | https://openalex.org/F4320337472 |
| funders[0].ror | https://ror.org/04pw6fb54 |
| funders[0].display_name | National Center for Advancing Translational Sciences |
| is_xpac | False |
| apc_list.value | 3950 |
| apc_list.currency | USD |
| apc_list.value_usd | 3950 |
| apc_paid.value | 3950 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 3950 |
| concepts[0].id | https://openalex.org/C23131810 |
| concepts[0].level | 2 |
| concepts[0].score | 0.7597081661224365 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q818574 |
| concepts[0].display_name | Observational study |
| concepts[1].id | https://openalex.org/C2778515351 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7464771866798401 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q9622 |
| concepts[1].display_name | Scalp |
| concepts[2].id | https://openalex.org/C2778186239 |
| concepts[2].level | 2 |
| concepts[2].score | 0.7187268733978271 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q41571 |
| concepts[2].display_name | Epilepsy |
| concepts[3].id | https://openalex.org/C522805319 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6494433283805847 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q179965 |
| concepts[3].display_name | Electroencephalography |
| concepts[4].id | https://openalex.org/C548259974 |
| concepts[4].level | 1 |
| concepts[4].score | 0.5034677386283875 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q569965 |
| concepts[4].display_name | Audiology |
| concepts[5].id | https://openalex.org/C71924100 |
| concepts[5].level | 0 |
| concepts[5].score | 0.4551543891429901 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[5].display_name | Medicine |
| concepts[6].id | https://openalex.org/C15744967 |
| concepts[6].level | 0 |
| concepts[6].score | 0.4397452473640442 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q9418 |
| concepts[6].display_name | Psychology |
| concepts[7].id | https://openalex.org/C187212893 |
| concepts[7].level | 1 |
| concepts[7].score | 0.3734316825866699 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q123028 |
| concepts[7].display_name | Pediatrics |
| concepts[8].id | https://openalex.org/C118552586 |
| concepts[8].level | 1 |
| concepts[8].score | 0.28860631585121155 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q7867 |
| concepts[8].display_name | Psychiatry |
| concepts[9].id | https://openalex.org/C141071460 |
| concepts[9].level | 1 |
| concepts[9].score | 0.13655024766921997 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q40821 |
| concepts[9].display_name | Surgery |
| concepts[10].id | https://openalex.org/C126322002 |
| concepts[10].level | 1 |
| concepts[10].score | 0.08750346302986145 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[10].display_name | Internal medicine |
| keywords[0].id | https://openalex.org/keywords/observational-study |
| keywords[0].score | 0.7597081661224365 |
| keywords[0].display_name | Observational study |
| keywords[1].id | https://openalex.org/keywords/scalp |
| keywords[1].score | 0.7464771866798401 |
| keywords[1].display_name | Scalp |
| keywords[2].id | https://openalex.org/keywords/epilepsy |
| keywords[2].score | 0.7187268733978271 |
| keywords[2].display_name | Epilepsy |
| keywords[3].id | https://openalex.org/keywords/electroencephalography |
| keywords[3].score | 0.6494433283805847 |
| keywords[3].display_name | Electroencephalography |
| keywords[4].id | https://openalex.org/keywords/audiology |
| keywords[4].score | 0.5034677386283875 |
| keywords[4].display_name | Audiology |
| keywords[5].id | https://openalex.org/keywords/medicine |
| keywords[5].score | 0.4551543891429901 |
| keywords[5].display_name | Medicine |
| keywords[6].id | https://openalex.org/keywords/psychology |
| keywords[6].score | 0.4397452473640442 |
| keywords[6].display_name | Psychology |
| keywords[7].id | https://openalex.org/keywords/pediatrics |
| keywords[7].score | 0.3734316825866699 |
| keywords[7].display_name | Pediatrics |
| keywords[8].id | https://openalex.org/keywords/psychiatry |
| keywords[8].score | 0.28860631585121155 |
| keywords[8].display_name | Psychiatry |
| keywords[9].id | https://openalex.org/keywords/surgery |
| keywords[9].score | 0.13655024766921997 |
| keywords[9].display_name | Surgery |
| keywords[10].id | https://openalex.org/keywords/internal-medicine |
| keywords[10].score | 0.08750346302986145 |
| keywords[10].display_name | Internal medicine |
| language | en |
| locations[0].id | doi:10.1111/epi.16379 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S203153751 |
| locations[0].source.issn | 0013-9580, 1528-1157, 1528-1167 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0013-9580 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Epilepsia |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_lineage_names | Wiley |
| locations[0].license | cc-by-nc |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Epilepsia |
| locations[0].landing_page_url | https://doi.org/10.1111/epi.16379 |
| locations[1].id | pmid:31691264 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Epilepsia |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/31691264 |
| locations[2].id | pmh:oai:europepmc.org:5926813 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306400806 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | Europe PMC (PubMed Central) |
| locations[2].source.host_organization | https://openalex.org/I1303153112 |
| locations[2].source.host_organization_name | European Bioinformatics Institute |
| locations[2].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/6910957 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5102002693 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-3502-788X |
| authorships[0].author.display_name | Joyce Y. Wu |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I161318765, https://openalex.org/I4210134385 |
| authorships[0].affiliations[0].raw_affiliation_string | Division of Pediatric Neurology, UCLA Mattel Children's Hospital, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California |
| authorships[0].institutions[0].id | https://openalex.org/I4210134385 |
| authorships[0].institutions[0].ror | https://ror.org/04p5baq95 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I2799798094, https://openalex.org/I4210134385 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Mattel Children's Hospital |
| authorships[0].institutions[1].id | https://openalex.org/I161318765 |
| authorships[0].institutions[1].ror | https://ror.org/046rm7j60 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I161318765 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | University of California, Los Angeles |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Joyce Y. Wu |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Division of Pediatric Neurology, UCLA Mattel Children's Hospital, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California |
| authorships[1].author.id | https://openalex.org/A5104044220 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Monisha Goyal |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[1].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[1].institutions[0].id | https://openalex.org/I32389192 |
| authorships[1].institutions[0].ror | https://ror.org/008s83205 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Monisha Goyal |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[2].author.id | https://openalex.org/A5077316104 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-6725-2814 |
| authorships[2].author.display_name | Jurriaan M. Peters |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I1288882113 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Neurology, Boston Children's Hospital, Boston, Massachusetts |
| authorships[2].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[2].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Boston Children's Hospital |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Jurriaan M. Peters |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Neurology, Boston Children's Hospital, Boston, Massachusetts |
| authorships[3].author.id | https://openalex.org/A5008873914 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-7250-7391 |
| authorships[3].author.display_name | Darcy A. Krueger |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I1285204247 |
| authorships[3].affiliations[0].raw_affiliation_string | Cincinnati Children's Hospital, Cincinnati, Ohio |
| authorships[3].institutions[0].id | https://openalex.org/I1285204247 |
| authorships[3].institutions[0].ror | https://ror.org/01hcyya48 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I1285204247 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Cincinnati Children's Hospital Medical Center |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Darcy Krueger |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Cincinnati Children's Hospital, Cincinnati, Ohio |
| authorships[4].author.id | https://openalex.org/A5079691093 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-7044-2953 |
| authorships[4].author.display_name | Mustafa Şahin |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I1288882113 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Neurology, Boston Children's Hospital, Boston, Massachusetts |
| authorships[4].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[4].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | Boston Children's Hospital |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Mustafa Sahin |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Neurology, Boston Children's Hospital, Boston, Massachusetts |
| authorships[5].author.id | https://openalex.org/A5073230151 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-2892-0840 |
| authorships[5].author.display_name | Hope Northrup |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I919571938 |
| authorships[5].affiliations[0].raw_affiliation_string | University of Texas Health Science Center Houston, Houston, Texas |
| authorships[5].institutions[0].id | https://openalex.org/I919571938 |
| authorships[5].institutions[0].ror | https://ror.org/03gds6c39 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I919571938 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | The University of Texas Health Science Center at Houston |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Hope Northrup |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | University of Texas Health Science Center Houston, Houston, Texas |
| authorships[6].author.id | https://openalex.org/A5055437313 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-2694-5833 |
| authorships[6].author.display_name | Kit Sing Au |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I919571938 |
| authorships[6].affiliations[0].raw_affiliation_string | University of Texas Health Science Center Houston, Houston, Texas |
| authorships[6].institutions[0].id | https://openalex.org/I919571938 |
| authorships[6].institutions[0].ror | https://ror.org/03gds6c39 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I919571938 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | The University of Texas Health Science Center at Houston |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Kit S. Au |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | University of Texas Health Science Center Houston, Houston, Texas |
| authorships[7].author.id | https://openalex.org/A5021072194 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-6025-0074 |
| authorships[7].author.display_name | Sarah O’Kelley |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[7].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[7].institutions[0].id | https://openalex.org/I32389192 |
| authorships[7].institutions[0].ror | https://ror.org/008s83205 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Sarah O’Kelley |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[8].author.id | https://openalex.org/A5075514097 |
| authorships[8].author.orcid | https://orcid.org/0000-0003-1365-919X |
| authorships[8].author.display_name | Marian E. Williams |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I1336910626 |
| authorships[8].affiliations[0].raw_affiliation_string | Children's Hospital Los Angeles, Los Angeles, California |
| authorships[8].institutions[0].id | https://openalex.org/I1336910626 |
| authorships[8].institutions[0].ror | https://ror.org/00412ts95 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I1336910626 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Children's Hospital of Los Angeles |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Marian Williams |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Children's Hospital Los Angeles, Los Angeles, California |
| authorships[9].author.id | https://openalex.org/A5081010890 |
| authorships[9].author.orcid | https://orcid.org/0000-0003-2047-1013 |
| authorships[9].author.display_name | Deborah A. Pearson |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I919571938 |
| authorships[9].affiliations[0].raw_affiliation_string | University of Texas Health Science Center Houston, Houston, Texas |
| authorships[9].institutions[0].id | https://openalex.org/I919571938 |
| authorships[9].institutions[0].ror | https://ror.org/03gds6c39 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I919571938 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | The University of Texas Health Science Center at Houston |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Deborah A. Pearson |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | University of Texas Health Science Center Houston, Houston, Texas |
| authorships[10].author.id | https://openalex.org/A5032537143 |
| authorships[10].author.orcid | https://orcid.org/0000-0003-0828-3677 |
| authorships[10].author.display_name | Ellen Hanson |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I1288882113 |
| authorships[10].affiliations[0].raw_affiliation_string | Department of Neurology, Boston Children's Hospital, Boston, Massachusetts |
| authorships[10].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[10].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[10].institutions[0].type | healthcare |
| authorships[10].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | Boston Children's Hospital |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Ellen Hanson |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Department of Neurology, Boston Children's Hospital, Boston, Massachusetts |
| authorships[11].author.id | https://openalex.org/A5044165381 |
| authorships[11].author.orcid | https://orcid.org/0000-0002-3929-6107 |
| authorships[11].author.display_name | Anna W. Byars |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I1285204247 |
| authorships[11].affiliations[0].raw_affiliation_string | Cincinnati Children's Hospital, Cincinnati, Ohio |
| authorships[11].institutions[0].id | https://openalex.org/I1285204247 |
| authorships[11].institutions[0].ror | https://ror.org/01hcyya48 |
| authorships[11].institutions[0].type | healthcare |
| authorships[11].institutions[0].lineage | https://openalex.org/I1285204247 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | Cincinnati Children's Hospital Medical Center |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Anna W. Byars |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Cincinnati Children's Hospital, Cincinnati, Ohio |
| authorships[12].author.id | https://openalex.org/A5059587415 |
| authorships[12].author.orcid | |
| authorships[12].author.display_name | Jessica Krefting |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[12].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[12].institutions[0].id | https://openalex.org/I32389192 |
| authorships[12].institutions[0].ror | https://ror.org/008s83205 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[12].institutions[0].country_code | US |
| authorships[12].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Jessica Krefting |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[13].author.id | https://openalex.org/A5108469882 |
| authorships[13].author.orcid | https://orcid.org/0009-0007-2251-5661 |
| authorships[13].author.display_name | Mark Beasley |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[13].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[13].institutions[0].id | https://openalex.org/I32389192 |
| authorships[13].institutions[0].ror | https://ror.org/008s83205 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Mark Beasley |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[14].author.id | https://openalex.org/A5036008316 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-8455-980X |
| authorships[14].author.display_name | Gary Cutter |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[14].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[14].institutions[0].id | https://openalex.org/I32389192 |
| authorships[14].institutions[0].ror | https://ror.org/008s83205 |
| authorships[14].institutions[0].type | education |
| authorships[14].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Gary Cutter |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[15].author.id | https://openalex.org/A5079771081 |
| authorships[15].author.orcid | https://orcid.org/0000-0002-4672-8406 |
| authorships[15].author.display_name | Nita A. Limdi |
| authorships[15].countries | US |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[15].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[15].institutions[0].id | https://openalex.org/I32389192 |
| authorships[15].institutions[0].ror | https://ror.org/008s83205 |
| authorships[15].institutions[0].type | education |
| authorships[15].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[15].institutions[0].country_code | US |
| authorships[15].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Nita Limdi |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[16].author.id | https://openalex.org/A5113172648 |
| authorships[16].author.orcid | |
| authorships[16].author.display_name | E. Martina Bebin |
| authorships[16].countries | US |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I32389192 |
| authorships[16].affiliations[0].raw_affiliation_string | University of Alabama Birmingham, Birmingham, Alabama |
| authorships[16].institutions[0].id | https://openalex.org/I32389192 |
| authorships[16].institutions[0].ror | https://ror.org/008s83205 |
| authorships[16].institutions[0].type | education |
| authorships[16].institutions[0].lineage | https://openalex.org/I32389192 |
| authorships[16].institutions[0].country_code | US |
| authorships[16].institutions[0].display_name | University of Alabama at Birmingham |
| authorships[16].author_position | last |
| authorships[16].raw_author_name | E. Martina Bebin |
| authorships[16].is_corresponding | True |
| authorships[16].raw_affiliation_strings | University of Alabama Birmingham, Birmingham, Alabama |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1111/epi.16379 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T12049 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2737 |
| primary_topic.subfield.display_name | Physiology |
| primary_topic.display_name | Tuberous Sclerosis Complex Research |
| related_works | https://openalex.org/W2126108552, https://openalex.org/W2008167394, https://openalex.org/W36837324, https://openalex.org/W4381328000, https://openalex.org/W2588429911, https://openalex.org/W2071974719, https://openalex.org/W2109147503, https://openalex.org/W3037660442, https://openalex.org/W4403270130, https://openalex.org/W1971410108 |
| cited_by_count | 61 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 7 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 9 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 10 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 7 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 15 |
| counts_by_year[5].year | 2020 |
| counts_by_year[5].cited_by_count | 11 |
| counts_by_year[6].year | 2019 |
| counts_by_year[6].cited_by_count | 2 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1111/epi.16379 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S203153751 |
| best_oa_location.source.issn | 0013-9580, 1528-1157, 1528-1167 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0013-9580 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Epilepsia |
| best_oa_location.source.host_organization | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_name | Wiley |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_lineage_names | Wiley |
| best_oa_location.license | cc-by-nc |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Epilepsia |
| best_oa_location.landing_page_url | https://doi.org/10.1111/epi.16379 |
| primary_location.id | doi:10.1111/epi.16379 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S203153751 |
| primary_location.source.issn | 0013-9580, 1528-1157, 1528-1167 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0013-9580 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Epilepsia |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_lineage_names | Wiley |
| primary_location.license | cc-by-nc |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Epilepsia |
| primary_location.landing_page_url | https://doi.org/10.1111/epi.16379 |
| publication_date | 2019-11-05 |
| publication_year | 2019 |
| referenced_works | https://openalex.org/W2565940784, https://openalex.org/W2383259826, https://openalex.org/W2336586723, https://openalex.org/W1886226115, https://openalex.org/W2053956592, https://openalex.org/W2105558792, https://openalex.org/W1803495774, https://openalex.org/W2082407534, https://openalex.org/W2608937503, https://openalex.org/W2766480612, https://openalex.org/W2126467306, https://openalex.org/W2948816809, https://openalex.org/W4301049852, https://openalex.org/W2982862638, https://openalex.org/W4253104584 |
| referenced_works_count | 15 |
| abstract_inverted_index.2 | 75, 196, 298 |
| abstract_inverted_index.7 | 26 |
| abstract_inverted_index.= | 159 |
| abstract_inverted_index.a | 150, 180, 187, 250, 260 |
| abstract_inverted_index.24 | 90 |
| abstract_inverted_index.32 | 104, 144 |
| abstract_inverted_index.40 | 96 |
| abstract_inverted_index.6, | 87 |
| abstract_inverted_index.At | 57 |
| abstract_inverted_index.Of | 95 |
| abstract_inverted_index.To | 2 |
| abstract_inverted_index.as | 259 |
| abstract_inverted_index.at | 86, 149, 297 |
| abstract_inverted_index.be | 257 |
| abstract_inverted_index.by | 195, 205 |
| abstract_inverted_index.if | 4 |
| abstract_inverted_index.in | 8, 215, 238, 265 |
| abstract_inverted_index.of | 28, 50, 77, 92, 101, 138, 142, 153, 173, 177, 198, 242, 249, 278, 284, 300 |
| abstract_inverted_index.on | 130, 291 |
| abstract_inverted_index.or | 30, 36, 52, 227, 282 |
| abstract_inverted_index.to | 111, 122, 135 |
| abstract_inverted_index.12, | 88 |
| abstract_inverted_index.3.6 | 206 |
| abstract_inverted_index.7.5 | 154 |
| abstract_inverted_index.70% | 188 |
| abstract_inverted_index.EEG | 132, 255 |
| abstract_inverted_index.The | 247 |
| abstract_inverted_index.Two | 108 |
| abstract_inverted_index.age | 29, 100, 152 |
| abstract_inverted_index.all | 70 |
| abstract_inverted_index.and | 19, 32, 62, 65, 82, 89, 113, 164, 185, 253, 294 |
| abstract_inverted_index.but | 220, 267, 275 |
| abstract_inverted_index.can | 16, 256 |
| abstract_inverted_index.due | 121 |
| abstract_inverted_index.for | 40, 170, 192, 262 |
| abstract_inverted_index.had | 179 |
| abstract_inverted_index.low | 289 |
| abstract_inverted_index.not | 168, 221, 268, 276 |
| abstract_inverted_index.six | 114 |
| abstract_inverted_index.the | 34, 106, 136, 143, 171, 239, 292 |
| abstract_inverted_index.use | 248 |
| abstract_inverted_index.who | 223 |
| abstract_inverted_index.82.4 | 102 |
| abstract_inverted_index.IEDs | 178, 200, 234 |
| abstract_inverted_index.TSC. | 246, 272 |
| abstract_inverted_index.[SD] | 158 |
| abstract_inverted_index.age. | 78, 93, 199, 301 |
| abstract_inverted_index.all, | 269 |
| abstract_inverted_index.came | 230 |
| abstract_inverted_index.each | 58 |
| abstract_inverted_index.lost | 110 |
| abstract_inverted_index.mean | 151 |
| abstract_inverted_index.only | 214 |
| abstract_inverted_index.used | 258 |
| abstract_inverted_index.were | 43, 72, 84, 109, 115, 167 |
| abstract_inverted_index.with | 11, 54, 117, 217, 245, 271, 288 |
| abstract_inverted_index.(77%) | 241 |
| abstract_inverted_index.(EEG) | 7 |
| abstract_inverted_index.(TSC) | 15 |
| abstract_inverted_index.(mean | 99 |
| abstract_inverted_index.4.4). | 160 |
| abstract_inverted_index.77.3% | 181 |
| abstract_inverted_index.Forty | 24 |
| abstract_inverted_index.awake | 64, 252 |
| abstract_inverted_index.drugs | 119 |
| abstract_inverted_index.most, | 266 |
| abstract_inverted_index.never | 224 |
| abstract_inverted_index.onset | 137, 204 |
| abstract_inverted_index.prior | 48, 134 |
| abstract_inverted_index.tests | 296 |
| abstract_inverted_index.their | 131 |
| abstract_inverted_index.under | 231 |
| abstract_inverted_index.until | 74 |
| abstract_inverted_index.value | 184, 191 |
| abstract_inverted_index.whose | 228 |
| abstract_inverted_index.years | 76, 197, 299 |
| abstract_inverted_index.(AEDs) | 120 |
| abstract_inverted_index.(IEDs) | 129 |
| abstract_inverted_index.Mullen | 295 |
| abstract_inverted_index.across | 69 |
| abstract_inverted_index.and/or | 125 |
| abstract_inverted_index.asleep | 66, 254 |
| abstract_inverted_index.days), | 103 |
| abstract_inverted_index.months | 27, 91, 155, 207 |
| abstract_inverted_index.scores | 290 |
| abstract_inverted_index.showed | 211 |
| abstract_inverted_index.sites, | 71 |
| abstract_inverted_index.study. | 107 |
| abstract_inverted_index.visit, | 59 |
| abstract_inverted_index.(Mullen | 81 |
| abstract_inverted_index.(mean). | 208 |
| abstract_inverted_index.Methods | 23 |
| abstract_inverted_index.Results | 94 |
| abstract_inverted_index.absence | 186 |
| abstract_inverted_index.complex | 14 |
| abstract_inverted_index.genetic | 35 |
| abstract_inverted_index.history | 49, 61, 277, 283 |
| abstract_inverted_index.infants | 10, 25, 97, 216, 222, 244, 270 |
| abstract_inverted_index.meeting | 33 |
| abstract_inverted_index.ongoing | 218, 263 |
| abstract_inverted_index.predict | 17 |
| abstract_inverted_index.routine | 5 |
| abstract_inverted_index.seizure | 60, 203 |
| abstract_inverted_index.studies | 133 |
| abstract_inverted_index.testing | 210 |
| abstract_inverted_index.treated | 116 |
| abstract_inverted_index.younger | 31 |
| abstract_inverted_index.1‐hour | 63, 251 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Presence | 176 |
| abstract_inverted_index.Vineland | 293 |
| abstract_inverted_index.activity | 281 |
| abstract_inverted_index.children | 146 |
| abstract_inverted_index.clinical | 37, 139, 174, 202 |
| abstract_inverted_index.control. | 232 |
| abstract_inverted_index.criteria | 39, 46 |
| abstract_inverted_index.decline, | 213 |
| abstract_inverted_index.enrolled | 98 |
| abstract_inverted_index.epilepsy | 18, 148, 237 |
| abstract_inverted_index.identify | 235 |
| abstract_inverted_index.included | 47 |
| abstract_inverted_index.majority | 240 |
| abstract_inverted_index.negative | 189 |
| abstract_inverted_index.obtained | 73 |
| abstract_inverted_index.positive | 182 |
| abstract_inverted_index.preceded | 201 |
| abstract_inverted_index.seizures | 51, 124, 194, 226, 229 |
| abstract_inverted_index.slowing, | 162 |
| abstract_inverted_index.tuberous | 12, 41 |
| abstract_inverted_index.(standard | 156 |
| abstract_inverted_index.Exclusion | 45 |
| abstract_inverted_index.Objective | 1 |
| abstract_inverted_index.Seventeen | 141 |
| abstract_inverted_index.biomarker | 261 |
| abstract_inverted_index.completed | 85, 105 |
| abstract_inverted_index.determine | 3 |
| abstract_inverted_index.developed | 147, 225 |
| abstract_inverted_index.deviation | 157 |
| abstract_inverted_index.enrolled. | 44 |
| abstract_inverted_index.impending | 236 |
| abstract_inverted_index.outcomes. | 22 |
| abstract_inverted_index.remaining | 145 |
| abstract_inverted_index.sclerosis | 13, 42 |
| abstract_inverted_index.seizures, | 219, 274, 286 |
| abstract_inverted_index.seizures. | 140, 175 |
| abstract_inverted_index.treatment | 53 |
| abstract_inverted_index.Persistent | 273 |
| abstract_inverted_index.correlated | 287 |
| abstract_inverted_index.developing | 193 |
| abstract_inverted_index.diagnostic | 38 |
| abstract_inverted_index.discharges | 128 |
| abstract_inverted_index.interictal | 126, 279 |
| abstract_inverted_index.predictive | 169, 183, 190 |
| abstract_inverted_index.subsequent | 20 |
| abstract_inverted_index.antiseizure | 55 |
| abstract_inverted_index.assessments | 80 |
| abstract_inverted_index.attenuation | 166 |
| abstract_inverted_index.development | 172 |
| abstract_inverted_index.follow‐up | 112 |
| abstract_inverted_index.significant | 212 |
| abstract_inverted_index.Significance | 233 |
| abstract_inverted_index.epileptiform | 127, 280 |
| abstract_inverted_index.medications. | 56 |
| abstract_inverted_index.standardized | 68 |
| abstract_inverted_index.video‐EEG, | 67 |
| abstract_inverted_index.Developmental | 79, 209 |
| abstract_inverted_index.antiepileptic | 118 |
| abstract_inverted_index.Vineland‐II) | 83 |
| abstract_inverted_index.electrographic | 123 |
| abstract_inverted_index.neurocognitive | 21 |
| abstract_inverted_index.epileptogenesis | 264 |
| abstract_inverted_index.hypsarrhythmia, | 163 |
| abstract_inverted_index.seizure‐naive | 9, 243 |
| abstract_inverted_index.Generalized/focal | 161 |
| abstract_inverted_index.generalized/focal | 165 |
| abstract_inverted_index.well‐controlled | 285 |
| abstract_inverted_index.electroencephalography | 6 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 94 |
| corresponding_author_ids | https://openalex.org/A5113172648 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 17 |
| corresponding_institution_ids | https://openalex.org/I32389192 |
| citation_normalized_percentile.value | 0.95522208 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |