scMoresDB: A comprehensive database of single-cell multi-omics data for human respiratory system Article Swipe
Kang Chen
,
Yutong Han
,
Yanni Wang
,
Dingli Zhou
,
Fanjie Wu
,
Wenhao Cai
,
Shikang Zheng
,
Qinyuan Xiao
,
Haiyue Zhang
,
Weizhong Li
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1016/j.isci.2024.109567
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1016/j.isci.2024.109567
The human respiratory system is a complex and important system that can suffer a variety of diseases. Single-cell sequencing technologies, applied in many respiratory disease studies, have enhanced our ability in characterizing molecular and phenotypic features at a single-cell resolution. The exponentially increasing data from these studies have consequently led to difficulties in data sharing and analysis. Here, we present scMoresDB, a single-cell multi-omics database platform with extensive omics types tailored for human respiratory diseases. scMoresDB re-analyzes single-cell multi-omics datasets, providing a user-friendly interface with cross-omics search capabilities, interactive visualizations, and analytical tools for comprehensive data sharing and integrative analysis. Our example applications highlight the potential significance of BSG receptor in SARS-CoV-2 infection as well as the involvement of HHIP and TGFB2 in the development and progression of chronic obstructive pulmonary disease. scMoresDB significantly increases accessibility and utility of single-cell data relevant to human respiratory system and associated diseases.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.isci.2024.109567
- OA Status
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- Cited By
- 4
- References
- 60
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4393198111Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.isci.2024.109567Digital Object Identifier
- Title
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scMoresDB: A comprehensive database of single-cell multi-omics data for human respiratory systemWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-03-26Full publication date if available
- Authors
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Kang Chen, Yutong Han, Yanni Wang, Dingli Zhou, Fanjie Wu, Wenhao Cai, Shikang Zheng, Qinyuan Xiao, Haiyue Zhang, Weizhong LiList of authors in order
- Landing page
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https://doi.org/10.1016/j.isci.2024.109567Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1016/j.isci.2024.109567Direct OA link when available
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Omics, Systems biology, Computer science, Computational biology, Data sharing, Bioinformatics, Biology, Medicine, Pathology, Alternative medicineTop concepts (fields/topics) attached by OpenAlex
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4Total citation count in OpenAlex
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2025: 3, 2024: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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