Seven myths of how transcription factors read the cis-regulatory code Article Swipe
Genomics data are now being generated at large quantities, of exquisite high resolution and from single cells. They offer a unique opportunity to develop powerful machine learning algorithms, including neural networks, to uncover the rules of the cis-regulatory code. However, current modeling assumptions are often not based on state-of-the-art knowledge of the cis-regulatory code from transcription, developmental genetics, imaging and structural studies. Here I aim to fill this gap by giving a brief historical overview of the field, describing common misconceptions and providing knowledge that might help to guide computational approaches. I will describe the principles and mechanisms involved in the combinatorial requirement of transcription factor binding motifs for enhancer activity, including the role of chromatin accessibility, repressors and low-affinity motifs in the cis-regulatory code. Deciphering the cis-regulatory code would unlock an enormous amount of regulatory information in the genome and would allow us to locate cis-regulatory genetic variants involved in development and disease.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.coisb.2020.08.002
- OA Status
- hybrid
- Cited By
- 114
- References
- 89
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3083240949
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3083240949Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.coisb.2020.08.002Digital Object Identifier
- Title
-
Seven myths of how transcription factors read the cis-regulatory codeWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-09-04Full publication date if available
- Authors
-
Julia ZeitlingerList of authors in order
- Landing page
-
https://doi.org/10.1016/j.coisb.2020.08.002Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1016/j.coisb.2020.08.002Direct OA link when available
- Concepts
-
Enhancer, Computational biology, Chromatin, Computer science, Transcription factor, Biology, Genetics, GeneTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
114Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 20, 2024: 28, 2023: 30, 2022: 19, 2021: 17Per-year citation counts (last 5 years)
- References (count)
-
89Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3083240949 |
|---|---|
| doi | https://doi.org/10.1016/j.coisb.2020.08.002 |
| ids.doi | https://doi.org/10.1016/j.coisb.2020.08.002 |
| ids.mag | 3083240949 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/33134611 |
| ids.openalex | https://openalex.org/W3083240949 |
| fwci | 6.43678023 |
| type | article |
| title | Seven myths of how transcription factors read the cis-regulatory code |
| awards[0].id | https://openalex.org/G4425784504 |
| awards[0].funder_id | https://openalex.org/F4320332161 |
| awards[0].display_name | |
| awards[0].funder_award_id | 1R01HG010211 |
| awards[0].funder_display_name | National Institutes of Health |
| biblio.issue | |
| biblio.volume | 23 |
| biblio.last_page | 31 |
| biblio.first_page | 22 |
| topics[0].id | https://openalex.org/T10222 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | Genomics and Chromatin Dynamics |
| topics[1].id | https://openalex.org/T10604 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9973999857902527 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | RNA Research and Splicing |
| topics[2].id | https://openalex.org/T10184 |
| topics[2].field.id | https://openalex.org/fields/11 |
| topics[2].field.display_name | Agricultural and Biological Sciences |
| topics[2].score | 0.9940999746322632 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1110 |
| topics[2].subfield.display_name | Plant Science |
| topics[2].display_name | Plant Molecular Biology Research |
| funders[0].id | https://openalex.org/F4320310084 |
| funders[0].ror | https://ror.org/04bgfm609 |
| funders[0].display_name | Stowers Institute for Medical Research |
| funders[1].id | https://openalex.org/F4320332161 |
| funders[1].ror | https://ror.org/01cwqze88 |
| funders[1].display_name | National Institutes of Health |
| is_xpac | False |
| apc_list.value | 3500 |
| apc_list.currency | USD |
| apc_list.value_usd | 3500 |
| apc_paid.value | 3500 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 3500 |
| concepts[0].id | https://openalex.org/C111936080 |
| concepts[0].level | 4 |
| concepts[0].score | 0.6320681571960449 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q913367 |
| concepts[0].display_name | Enhancer |
| concepts[1].id | https://openalex.org/C70721500 |
| concepts[1].level | 1 |
| concepts[1].score | 0.5906295776367188 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q177005 |
| concepts[1].display_name | Computational biology |
| concepts[2].id | https://openalex.org/C83640560 |
| concepts[2].level | 3 |
| concepts[2].score | 0.47728171944618225 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q180951 |
| concepts[2].display_name | Chromatin |
| concepts[3].id | https://openalex.org/C41008148 |
| concepts[3].level | 0 |
| concepts[3].score | 0.4637022614479065 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[3].display_name | Computer science |
| concepts[4].id | https://openalex.org/C86339819 |
| concepts[4].level | 3 |
| concepts[4].score | 0.4577324688434601 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q407384 |
| concepts[4].display_name | Transcription factor |
| concepts[5].id | https://openalex.org/C86803240 |
| concepts[5].level | 0 |
| concepts[5].score | 0.44854822754859924 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[5].display_name | Biology |
| concepts[6].id | https://openalex.org/C54355233 |
| concepts[6].level | 1 |
| concepts[6].score | 0.4383118152618408 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[6].display_name | Genetics |
| concepts[7].id | https://openalex.org/C104317684 |
| concepts[7].level | 2 |
| concepts[7].score | 0.23776152729988098 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[7].display_name | Gene |
| keywords[0].id | https://openalex.org/keywords/enhancer |
| keywords[0].score | 0.6320681571960449 |
| keywords[0].display_name | Enhancer |
| keywords[1].id | https://openalex.org/keywords/computational-biology |
| keywords[1].score | 0.5906295776367188 |
| keywords[1].display_name | Computational biology |
| keywords[2].id | https://openalex.org/keywords/chromatin |
| keywords[2].score | 0.47728171944618225 |
| keywords[2].display_name | Chromatin |
| keywords[3].id | https://openalex.org/keywords/computer-science |
| keywords[3].score | 0.4637022614479065 |
| keywords[3].display_name | Computer science |
| keywords[4].id | https://openalex.org/keywords/transcription-factor |
| keywords[4].score | 0.4577324688434601 |
| keywords[4].display_name | Transcription factor |
| keywords[5].id | https://openalex.org/keywords/biology |
| keywords[5].score | 0.44854822754859924 |
| keywords[5].display_name | Biology |
| keywords[6].id | https://openalex.org/keywords/genetics |
| keywords[6].score | 0.4383118152618408 |
| keywords[6].display_name | Genetics |
| keywords[7].id | https://openalex.org/keywords/gene |
| keywords[7].score | 0.23776152729988098 |
| keywords[7].display_name | Gene |
| language | en |
| locations[0].id | doi:10.1016/j.coisb.2020.08.002 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2764941636 |
| locations[0].source.issn | 2452-3100 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 2452-3100 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Current Opinion in Systems Biology |
| locations[0].source.host_organization | https://openalex.org/P4310320990 |
| locations[0].source.host_organization_name | Elsevier BV |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320990 |
| locations[0].source.host_organization_lineage_names | Elsevier BV |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Current Opinion in Systems Biology |
| locations[0].landing_page_url | https://doi.org/10.1016/j.coisb.2020.08.002 |
| locations[1].id | pmid:33134611 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Current opinion in systems biology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/33134611 |
| locations[2].id | pmh:oai:europepmc.org:7373132 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306400806 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | Europe PMC (PubMed Central) |
| locations[2].source.host_organization | https://openalex.org/I1303153112 |
| locations[2].source.host_organization_name | European Bioinformatics Institute |
| locations[2].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | http://europepmc.org/pmc/articles/PMC7592701 |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:7592701 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Curr Opin Syst Biol |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7592701 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5007801525 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-5172-3335 |
| authorships[0].author.display_name | Julia Zeitlinger |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210128618 |
| authorships[0].affiliations[0].raw_affiliation_string | The University of Kansas Medical Center, Kansas City, KS, USA |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I114131015 |
| authorships[0].affiliations[1].raw_affiliation_string | Stowers Institute for Medical Research, Kansas City, MO, USA |
| authorships[0].institutions[0].id | https://openalex.org/I114131015 |
| authorships[0].institutions[0].ror | https://ror.org/04bgfm609 |
| authorships[0].institutions[0].type | nonprofit |
| authorships[0].institutions[0].lineage | https://openalex.org/I114131015 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Stowers Institute for Medical Research |
| authorships[0].institutions[1].id | https://openalex.org/I4210128618 |
| authorships[0].institutions[1].ror | https://ror.org/036c9yv20 |
| authorships[0].institutions[1].type | healthcare |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210128618 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | University of Kansas Medical Center |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Julia Zeitlinger |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Stowers Institute for Medical Research, Kansas City, MO, USA, The University of Kansas Medical Center, Kansas City, KS, USA |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1016/j.coisb.2020.08.002 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Seven myths of how transcription factors read the cis-regulatory code |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10222 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | Genomics and Chromatin Dynamics |
| related_works | https://openalex.org/W4391375266, https://openalex.org/W2113330652, https://openalex.org/W4303699336, https://openalex.org/W2152841149, https://openalex.org/W2586783543, https://openalex.org/W4387598842, https://openalex.org/W4225831698, https://openalex.org/W2973036402, https://openalex.org/W3198436517, https://openalex.org/W1607718650 |
| cited_by_count | 114 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 20 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 28 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 30 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 19 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 17 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1016/j.coisb.2020.08.002 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764941636 |
| best_oa_location.source.issn | 2452-3100 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 2452-3100 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Current Opinion in Systems Biology |
| best_oa_location.source.host_organization | https://openalex.org/P4310320990 |
| best_oa_location.source.host_organization_name | Elsevier BV |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320990 |
| best_oa_location.source.host_organization_lineage_names | Elsevier BV |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Current Opinion in Systems Biology |
| best_oa_location.landing_page_url | https://doi.org/10.1016/j.coisb.2020.08.002 |
| primary_location.id | doi:10.1016/j.coisb.2020.08.002 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2764941636 |
| primary_location.source.issn | 2452-3100 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 2452-3100 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Current Opinion in Systems Biology |
| primary_location.source.host_organization | https://openalex.org/P4310320990 |
| primary_location.source.host_organization_name | Elsevier BV |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320990 |
| primary_location.source.host_organization_lineage_names | Elsevier BV |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Current Opinion in Systems Biology |
| primary_location.landing_page_url | https://doi.org/10.1016/j.coisb.2020.08.002 |
| publication_date | 2020-09-04 |
| publication_year | 2020 |
| referenced_works | https://openalex.org/W2801470635, https://openalex.org/W2032619610, https://openalex.org/W2007085003, https://openalex.org/W2067956561, https://openalex.org/W2068577315, https://openalex.org/W2148944713, https://openalex.org/W2125286524, https://openalex.org/W2064171951, https://openalex.org/W2141060672, https://openalex.org/W2151794037, https://openalex.org/W2086453622, https://openalex.org/W2308616703, https://openalex.org/W4246645317, https://openalex.org/W2082874386, https://openalex.org/W2128937741, https://openalex.org/W2150926065, https://openalex.org/W4248318091, https://openalex.org/W2026882865, https://openalex.org/W2080498142, https://openalex.org/W2077874719, https://openalex.org/W2022736304, https://openalex.org/W2045362835, https://openalex.org/W2001554877, https://openalex.org/W1989419347, https://openalex.org/W2068379897, https://openalex.org/W1602702667, https://openalex.org/W2736547131, https://openalex.org/W2935703330, https://openalex.org/W3000045279, https://openalex.org/W1019830208, https://openalex.org/W2198606573, https://openalex.org/W2345512687, https://openalex.org/W6781145772, https://openalex.org/W2019251848, https://openalex.org/W3013674494, https://openalex.org/W2014677321, https://openalex.org/W2603617582, https://openalex.org/W2062867942, https://openalex.org/W2481378334, https://openalex.org/W2110492953, https://openalex.org/W2909254802, https://openalex.org/W2169696276, https://openalex.org/W2057087360, https://openalex.org/W2488989538, https://openalex.org/W2007157318, https://openalex.org/W2141215651, https://openalex.org/W2087093185, https://openalex.org/W2623585200, https://openalex.org/W1928213240, https://openalex.org/W1977620504, https://openalex.org/W2281392042, https://openalex.org/W2575110262, https://openalex.org/W2255694509, https://openalex.org/W2122834462, https://openalex.org/W2018345118, https://openalex.org/W2966723103, https://openalex.org/W2118646732, https://openalex.org/W1987301268, https://openalex.org/W2096118921, https://openalex.org/W2027458139, https://openalex.org/W1976644679, https://openalex.org/W2171675401, https://openalex.org/W1989618744, https://openalex.org/W2782859294, https://openalex.org/W2518972560, https://openalex.org/W2556513628, https://openalex.org/W2917779347, https://openalex.org/W2806844404, https://openalex.org/W2049361027, https://openalex.org/W2046516300, https://openalex.org/W2054147565, https://openalex.org/W2554961135, https://openalex.org/W2125233822, https://openalex.org/W2028200156, https://openalex.org/W2314176140, https://openalex.org/W2787865536, https://openalex.org/W2961348108, https://openalex.org/W2968775930, https://openalex.org/W2162494256, https://openalex.org/W1994267372, https://openalex.org/W3008725968, https://openalex.org/W2790661277, https://openalex.org/W2002964220, https://openalex.org/W2159942968, https://openalex.org/W2118628540, https://openalex.org/W3043091519, https://openalex.org/W4246359243, https://openalex.org/W3130819465, https://openalex.org/W2969785451 |
| referenced_works_count | 89 |
| abstract_inverted_index.I | 63, 91 |
| abstract_inverted_index.a | 19, 71 |
| abstract_inverted_index.an | 131 |
| abstract_inverted_index.at | 6 |
| abstract_inverted_index.by | 69 |
| abstract_inverted_index.in | 99, 121, 137, 150 |
| abstract_inverted_index.of | 9, 35, 50, 75, 103, 114, 134 |
| abstract_inverted_index.on | 47 |
| abstract_inverted_index.to | 22, 31, 65, 87, 144 |
| abstract_inverted_index.us | 143 |
| abstract_inverted_index.aim | 64 |
| abstract_inverted_index.and | 13, 59, 81, 96, 118, 140, 152 |
| abstract_inverted_index.are | 2, 43 |
| abstract_inverted_index.for | 108 |
| abstract_inverted_index.gap | 68 |
| abstract_inverted_index.not | 45 |
| abstract_inverted_index.now | 3 |
| abstract_inverted_index.the | 33, 36, 51, 76, 94, 100, 112, 122, 126, 138 |
| abstract_inverted_index.Here | 62 |
| abstract_inverted_index.They | 17 |
| abstract_inverted_index.code | 53, 128 |
| abstract_inverted_index.data | 1 |
| abstract_inverted_index.fill | 66 |
| abstract_inverted_index.from | 14, 54 |
| abstract_inverted_index.help | 86 |
| abstract_inverted_index.high | 11 |
| abstract_inverted_index.role | 113 |
| abstract_inverted_index.that | 84 |
| abstract_inverted_index.this | 67 |
| abstract_inverted_index.will | 92 |
| abstract_inverted_index.allow | 142 |
| abstract_inverted_index.based | 46 |
| abstract_inverted_index.being | 4 |
| abstract_inverted_index.brief | 72 |
| abstract_inverted_index.code. | 38, 124 |
| abstract_inverted_index.guide | 88 |
| abstract_inverted_index.large | 7 |
| abstract_inverted_index.might | 85 |
| abstract_inverted_index.offer | 18 |
| abstract_inverted_index.often | 44 |
| abstract_inverted_index.rules | 34 |
| abstract_inverted_index.would | 129, 141 |
| abstract_inverted_index.amount | 133 |
| abstract_inverted_index.cells. | 16 |
| abstract_inverted_index.common | 79 |
| abstract_inverted_index.factor | 105 |
| abstract_inverted_index.field, | 77 |
| abstract_inverted_index.genome | 139 |
| abstract_inverted_index.giving | 70 |
| abstract_inverted_index.locate | 145 |
| abstract_inverted_index.motifs | 107, 120 |
| abstract_inverted_index.neural | 29 |
| abstract_inverted_index.single | 15 |
| abstract_inverted_index.unique | 20 |
| abstract_inverted_index.unlock | 130 |
| abstract_inverted_index.binding | 106 |
| abstract_inverted_index.current | 40 |
| abstract_inverted_index.develop | 23 |
| abstract_inverted_index.genetic | 147 |
| abstract_inverted_index.imaging | 58 |
| abstract_inverted_index.machine | 25 |
| abstract_inverted_index.uncover | 32 |
| abstract_inverted_index.Genomics | 0 |
| abstract_inverted_index.However, | 39 |
| abstract_inverted_index.describe | 93 |
| abstract_inverted_index.disease. | 153 |
| abstract_inverted_index.enhancer | 109 |
| abstract_inverted_index.enormous | 132 |
| abstract_inverted_index.involved | 98, 149 |
| abstract_inverted_index.learning | 26 |
| abstract_inverted_index.modeling | 41 |
| abstract_inverted_index.overview | 74 |
| abstract_inverted_index.powerful | 24 |
| abstract_inverted_index.studies. | 61 |
| abstract_inverted_index.variants | 148 |
| abstract_inverted_index.activity, | 110 |
| abstract_inverted_index.chromatin | 115 |
| abstract_inverted_index.exquisite | 10 |
| abstract_inverted_index.generated | 5 |
| abstract_inverted_index.genetics, | 57 |
| abstract_inverted_index.including | 28, 111 |
| abstract_inverted_index.knowledge | 49, 83 |
| abstract_inverted_index.networks, | 30 |
| abstract_inverted_index.providing | 82 |
| abstract_inverted_index.describing | 78 |
| abstract_inverted_index.historical | 73 |
| abstract_inverted_index.mechanisms | 97 |
| abstract_inverted_index.principles | 95 |
| abstract_inverted_index.regulatory | 135 |
| abstract_inverted_index.repressors | 117 |
| abstract_inverted_index.resolution | 12 |
| abstract_inverted_index.structural | 60 |
| abstract_inverted_index.Deciphering | 125 |
| abstract_inverted_index.algorithms, | 27 |
| abstract_inverted_index.approaches. | 90 |
| abstract_inverted_index.assumptions | 42 |
| abstract_inverted_index.development | 151 |
| abstract_inverted_index.information | 136 |
| abstract_inverted_index.opportunity | 21 |
| abstract_inverted_index.quantities, | 8 |
| abstract_inverted_index.requirement | 102 |
| abstract_inverted_index.low-affinity | 119 |
| abstract_inverted_index.combinatorial | 101 |
| abstract_inverted_index.computational | 89 |
| abstract_inverted_index.developmental | 56 |
| abstract_inverted_index.transcription | 104 |
| abstract_inverted_index.accessibility, | 116 |
| abstract_inverted_index.cis-regulatory | 37, 52, 123, 127, 146 |
| abstract_inverted_index.misconceptions | 80 |
| abstract_inverted_index.transcription, | 55 |
| abstract_inverted_index.state-of-the-art | 48 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 99 |
| corresponding_author_ids | https://openalex.org/A5007801525 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 1 |
| corresponding_institution_ids | https://openalex.org/I114131015, https://openalex.org/I4210128618 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/17 |
| sustainable_development_goals[0].score | 0.4399999976158142 |
| sustainable_development_goals[0].display_name | Partnerships for the goals |
| citation_normalized_percentile.value | 0.97232054 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |