Short- and long-term outcomes of patients with acute myocardial infarction complicated by cardiac arrest: a nationwide cohort study 2013–22 Article Swipe
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· 2024
· Open Access
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· DOI: https://doi.org/10.1093/ehjacc/zuae121
Aims To assess short- and long-term outcomes of acute myocardial infarction (AMI) complicated by out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA) in a nationwide cohort. Methods and results Cohort study of AMI patients admitted to hospitals in Norway 2013–22 registered in the Norwegian Myocardial Infarction Registry. Outcomes were in-hospital and long-term mortality. Cumulative mortality was assessed with the Kaplan–Meier and the life-table methods. Cox regression was used for risk comparisons. Among 105 439 AMI patients (35% women), we identified 3638 (3.5%) patients with OHCA and 2559 (2.4%) with IHCA. The mean age was 65.7 (13.2), 70.9 (12.6), and 70.7 (13.6) years for OHCA, IHCA, and AMI without cardiac arrest (CA), respectively. The median follow-up time was 3.3 (25th, 75th percentile: 1.1, 6.3) years. In-hospital mortality was 28, 49, and 5%, in OHCA, IHCA, and AMI without CA, and the estimated 5-year cumulative mortality was 48% [95% confidence interval (CI) 46–50%], 69% (95% CI 67–71%), and 35% (95% CI 34–35%), respectively. Among patients surviving to hospital discharge, no significant difference in mortality during follow-up was found between OHCA and AMI without CA [adjusted hazard ratio (HR) 1.04, 95% CI 0.96–1.13], while the long-term mortality of AMI patients with IHCA was higher (age-adjusted HR 1.31, 95% CI 1.19–1.45). Conclusion In this large, contemporary cohort of AMI patients, in-hospital mortality of patients with OHCA or IHCA was still high. Among patients surviving to hospital discharge, long-term mortality was comparable between OHCA and AMI without CA, while the outcome of patients with IHCA was significantly worse.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/ehjacc/zuae121
- OA Status
- hybrid
- Cited By
- 2
- References
- 35
- Related Works
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- OpenAlex ID
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4403674025Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/ehjacc/zuae121Digital Object Identifier
- Title
-
Short- and long-term outcomes of patients with acute myocardial infarction complicated by cardiac arrest: a nationwide cohort study 2013–22Work title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2024Year of publication
- Publication date
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2024-10-23Full publication date if available
- Authors
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Jarle Jortveit, Geir Øystein Andersen, Sigrun HalvorsenList of authors in order
- Landing page
-
https://doi.org/10.1093/ehjacc/zuae121Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1093/ehjacc/zuae121Direct OA link when available
- Concepts
-
Medicine, Myocardial infarction, Hazard ratio, Cohort, Internal medicine, Proportional hazards model, Cohort study, Cardiology, Confidence intervalTop concepts (fields/topics) attached by OpenAlex
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2Total citation count in OpenAlex
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2025: 2Per-year citation counts (last 5 years)
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35Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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