Short-term Frailty Index Fluctuations in Older Adults: Noise or Signal? Article Swipe
Erwin Stolz
,
Anna Schultz
,
Emiel O. Hoogendijk
,
Olga Theou
,
Kenneth Rockwood
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/gerona/glae262
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/gerona/glae262
Background Reversible short-term fluctuations in the frailty index (FI) are often thought of as representing only noise or error. Here, we assess (i) the size and source of short-term FI fluctuations, (ii) variation across sociodemographic characteristics, (iii) association with chronic diseases, (iv) correlation with age, frailty level, frailty change, and mortality, and (v) whether fluctuations reflect discrete health transitions. Methods Nationwide, biweekly longitudinal data from 426 community-dwelling older adults (70+) were collected in the FRequent health Assessment In Later life (FRAIL70+) study using a measurement burst design (5 122 repeated observations, median of 13 repeated observations per person). We calculated the intraindividual standard deviation of the FI and used location-scale mixed regression models. Results Mean intraindividual standard deviation was 0.04 (standard deviation = .03). Fluctuations were driven foremost by cognitive problems, somatic symptoms, and limitations in instrumental and mobility-related activities of daily living. Short-term fluctuations correlated with higher FI levels (r = 0.62), 1-year FI change (r = 0.26), and older age (+3% per year). Older adults who took to bed due to a health problem (+50%), those who had an overnight hospital stay (+50%), and those who died during follow-up (+44%) exhibited more FI fluctuations. Conclusions Short-term FI fluctuations were neither small nor random. Instead, as older adults become frailer, their measured health also becomes more unstable; hence, short-term fluctuations in overall health status can be seen as a concomitant phenomenon of the aging process. Researchers and clinicians should be aware of the existence of reversible fluctuations in the FI over weeks and months and its consequences for frailty monitoring.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/gerona/glae262
- OA Status
- hybrid
- Cited By
- 1
- References
- 80
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4404121493Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/gerona/glae262Digital Object Identifier
- Title
-
Short-term Frailty Index Fluctuations in Older Adults: Noise or Signal?Work title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-11-05Full publication date if available
- Authors
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Erwin Stolz, Anna Schultz, Emiel O. Hoogendijk, Olga Theou, Kenneth RockwoodList of authors in order
- Landing page
-
https://doi.org/10.1093/gerona/glae262Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1093/gerona/glae262Direct OA link when available
- Concepts
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Frailty Index, Gerontology, Demographics, Demography, Medicine, Term (time), Standard deviation, Noise (video), Statistics, Mathematics, Physics, Artificial intelligence, Image (mathematics), Quantum mechanics, Sociology, Computer scienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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80Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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