International Journal of Cancer • Vol 137 • No 10
Short‐term natural history of high‐risk human papillomavirus infection in mid‐adult women sampled monthly
May 2015 • Tsung‐chieh Fu, Long Fu Xi, Ayaka Hulbert, James P. Hughes, Qinghua Feng, Stephen M. Schwartz, Stephen E. Hawes, Laura A. Koutsky, Rachel L. Winer
Characterizing short‐term HPV detection patterns and viral load may inform HPV natural history in mid‐adult women. From 2011–2012, we recruited women aged 30–50 years. Women submitted monthly self‐collected vaginal samples for high‐risk HPV DNA testing for 6 months. Positive samples were tested for type‐specific HPV DNA load by real‐time PCR. HPV type‐adjusted linear and Poisson regression assessed factors associated with ( i ) viral load at initial HPV detection and ( ii ) repeat type‐specific HPV detection. One‐…