Site-Specific Modification Using the 2′-Methoxyethyl Group Improves the Specificity and Activity of siRNAs Article Swipe
Xinyun Song
,
Xiaoxia Wang
,
Yuan Ma
,
Zicai Liang
,
Zhenjun Yang
,
Huiqing Cao
·
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1016/j.omtn.2017.10.003
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1016/j.omtn.2017.10.003
Related Topics
Concepts
Small interfering RNA
Gene silencing
Trans-acting siRNA
RNA
Chemistry
Cleavage (geology)
RNA interference
Cell biology
RNA silencing
Molecular biology
Biology
Biochemistry
Gene
Fracture (geology)
Paleontology
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.omtn.2017.10.003
- http://www.cell.com/article/S2162253117302640/pdf
- OA Status
- gold
- Cited By
- 47
- References
- 35
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2763021074
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2763021074Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.omtn.2017.10.003Digital Object Identifier
- Title
-
Site-Specific Modification Using the 2′-Methoxyethyl Group Improves the Specificity and Activity of siRNAsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2017Year of publication
- Publication date
-
2017-10-12Full publication date if available
- Authors
-
Xinyun Song, Xiaoxia Wang, Yuan Ma, Zicai Liang, Zhenjun Yang, Huiqing CaoList of authors in order
- Landing page
-
https://doi.org/10.1016/j.omtn.2017.10.003Publisher landing page
- PDF URL
-
https://www.cell.com/article/S2162253117302640/pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.cell.com/article/S2162253117302640/pdfDirect OA link when available
- Concepts
-
Small interfering RNA, Gene silencing, Trans-acting siRNA, RNA, Chemistry, Cleavage (geology), RNA interference, Cell biology, RNA silencing, Molecular biology, Biology, Biochemistry, Gene, Fracture (geology), PaleontologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
47Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 12, 2024: 10, 2023: 8, 2022: 8, 2021: 4Per-year citation counts (last 5 years)
- References (count)
-
35Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2763021074 |
|---|---|
| doi | https://doi.org/10.1016/j.omtn.2017.10.003 |
| ids.doi | https://doi.org/10.1016/j.omtn.2017.10.003 |
| ids.mag | 2763021074 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/29246303 |
| ids.openalex | https://openalex.org/W2763021074 |
| fwci | 0.66807355 |
| type | article |
| title | Site-Specific Modification Using the 2′-Methoxyethyl Group Improves the Specificity and Activity of siRNAs |
| awards[0].id | https://openalex.org/G3099214895 |
| awards[0].funder_id | https://openalex.org/F4320321001 |
| awards[0].display_name | |
| awards[0].funder_award_id | 81473128 |
| awards[0].funder_display_name | National Natural Science Foundation of China |
| awards[1].id | https://openalex.org/G5797145276 |
| awards[1].funder_id | https://openalex.org/F4320321001 |
| awards[1].display_name | |
| awards[1].funder_award_id | 81570327 |
| awards[1].funder_display_name | National Natural Science Foundation of China |
| awards[2].id | https://openalex.org/G3211512218 |
| awards[2].funder_id | https://openalex.org/F4320321001 |
| awards[2].display_name | |
| awards[2].funder_award_id | 81502586 |
| awards[2].funder_display_name | National Natural Science Foundation of China |
| biblio.issue | |
| biblio.volume | 9 |
| biblio.last_page | 250 |
| biblio.first_page | 242 |
| topics[0].id | https://openalex.org/T10725 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | RNA Interference and Gene Delivery |
| topics[1].id | https://openalex.org/T10207 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9975000023841858 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Advanced biosensing and bioanalysis techniques |
| topics[2].id | https://openalex.org/T10062 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9973999857902527 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1306 |
| topics[2].subfield.display_name | Cancer Research |
| topics[2].display_name | MicroRNA in disease regulation |
| funders[0].id | https://openalex.org/F4320321001 |
| funders[0].ror | https://ror.org/01h0zpd94 |
| funders[0].display_name | National Natural Science Foundation of China |
| is_xpac | False |
| apc_list.value | 3900 |
| apc_list.currency | USD |
| apc_list.value_usd | 3900 |
| apc_paid.value | 3900 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 3900 |
| concepts[0].id | https://openalex.org/C22615655 |
| concepts[0].level | 4 |
| concepts[0].score | 0.9231858253479004 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q203221 |
| concepts[0].display_name | Small interfering RNA |
| concepts[1].id | https://openalex.org/C119056186 |
| concepts[1].level | 3 |
| concepts[1].score | 0.8046143054962158 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1431332 |
| concepts[1].display_name | Gene silencing |
| concepts[2].id | https://openalex.org/C60723119 |
| concepts[2].level | 5 |
| concepts[2].score | 0.7250151634216309 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q7833577 |
| concepts[2].display_name | Trans-acting siRNA |
| concepts[3].id | https://openalex.org/C67705224 |
| concepts[3].level | 3 |
| concepts[3].score | 0.49911975860595703 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11053 |
| concepts[3].display_name | RNA |
| concepts[4].id | https://openalex.org/C185592680 |
| concepts[4].level | 0 |
| concepts[4].score | 0.4660443067550659 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[4].display_name | Chemistry |
| concepts[5].id | https://openalex.org/C175156509 |
| concepts[5].level | 3 |
| concepts[5].score | 0.42270082235336304 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q1990218 |
| concepts[5].display_name | Cleavage (geology) |
| concepts[6].id | https://openalex.org/C166703698 |
| concepts[6].level | 4 |
| concepts[6].score | 0.42190882563591003 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q201993 |
| concepts[6].display_name | RNA interference |
| concepts[7].id | https://openalex.org/C95444343 |
| concepts[7].level | 1 |
| concepts[7].score | 0.4198231101036072 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7141 |
| concepts[7].display_name | Cell biology |
| concepts[8].id | https://openalex.org/C2191507 |
| concepts[8].level | 5 |
| concepts[8].score | 0.4112918972969055 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q7277185 |
| concepts[8].display_name | RNA silencing |
| concepts[9].id | https://openalex.org/C153911025 |
| concepts[9].level | 1 |
| concepts[9].score | 0.3547251224517822 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7202 |
| concepts[9].display_name | Molecular biology |
| concepts[10].id | https://openalex.org/C86803240 |
| concepts[10].level | 0 |
| concepts[10].score | 0.3348712623119354 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[10].display_name | Biology |
| concepts[11].id | https://openalex.org/C55493867 |
| concepts[11].level | 1 |
| concepts[11].score | 0.22468861937522888 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q7094 |
| concepts[11].display_name | Biochemistry |
| concepts[12].id | https://openalex.org/C104317684 |
| concepts[12].level | 2 |
| concepts[12].score | 0.2042911946773529 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[12].display_name | Gene |
| concepts[13].id | https://openalex.org/C43369102 |
| concepts[13].level | 2 |
| concepts[13].score | 0.0 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q2307625 |
| concepts[13].display_name | Fracture (geology) |
| concepts[14].id | https://openalex.org/C151730666 |
| concepts[14].level | 1 |
| concepts[14].score | 0.0 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q7205 |
| concepts[14].display_name | Paleontology |
| keywords[0].id | https://openalex.org/keywords/small-interfering-rna |
| keywords[0].score | 0.9231858253479004 |
| keywords[0].display_name | Small interfering RNA |
| keywords[1].id | https://openalex.org/keywords/gene-silencing |
| keywords[1].score | 0.8046143054962158 |
| keywords[1].display_name | Gene silencing |
| keywords[2].id | https://openalex.org/keywords/trans-acting-sirna |
| keywords[2].score | 0.7250151634216309 |
| keywords[2].display_name | Trans-acting siRNA |
| keywords[3].id | https://openalex.org/keywords/rna |
| keywords[3].score | 0.49911975860595703 |
| keywords[3].display_name | RNA |
| keywords[4].id | https://openalex.org/keywords/chemistry |
| keywords[4].score | 0.4660443067550659 |
| keywords[4].display_name | Chemistry |
| keywords[5].id | https://openalex.org/keywords/cleavage |
| keywords[5].score | 0.42270082235336304 |
| keywords[5].display_name | Cleavage (geology) |
| keywords[6].id | https://openalex.org/keywords/rna-interference |
| keywords[6].score | 0.42190882563591003 |
| keywords[6].display_name | RNA interference |
| keywords[7].id | https://openalex.org/keywords/cell-biology |
| keywords[7].score | 0.4198231101036072 |
| keywords[7].display_name | Cell biology |
| keywords[8].id | https://openalex.org/keywords/rna-silencing |
| keywords[8].score | 0.4112918972969055 |
| keywords[8].display_name | RNA silencing |
| keywords[9].id | https://openalex.org/keywords/molecular-biology |
| keywords[9].score | 0.3547251224517822 |
| keywords[9].display_name | Molecular biology |
| keywords[10].id | https://openalex.org/keywords/biology |
| keywords[10].score | 0.3348712623119354 |
| keywords[10].display_name | Biology |
| keywords[11].id | https://openalex.org/keywords/biochemistry |
| keywords[11].score | 0.22468861937522888 |
| keywords[11].display_name | Biochemistry |
| keywords[12].id | https://openalex.org/keywords/gene |
| keywords[12].score | 0.2042911946773529 |
| keywords[12].display_name | Gene |
| language | en |
| locations[0].id | doi:10.1016/j.omtn.2017.10.003 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2764969478 |
| locations[0].source.issn | 2162-2531 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2162-2531 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Molecular Therapy — Nucleic Acids |
| locations[0].source.host_organization | https://openalex.org/P4310315673 |
| locations[0].source.host_organization_name | Cell Press |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310315673, https://openalex.org/P4310320990 |
| locations[0].source.host_organization_lineage_names | Cell Press, Elsevier BV |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | http://www.cell.com/article/S2162253117302640/pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Molecular Therapy - Nucleic Acids |
| locations[0].landing_page_url | https://doi.org/10.1016/j.omtn.2017.10.003 |
| locations[1].id | pmid:29246303 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Molecular therapy. Nucleic acids |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/29246303 |
| locations[2].id | pmh:oai:doaj.org/article:0ad46dba85a643ed98d58e4d9f308868 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | cc-by-sa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | https://openalex.org/licenses/cc-by-sa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 242-250 (2017) |
| locations[2].landing_page_url | https://doaj.org/article/0ad46dba85a643ed98d58e4d9f308868 |
| locations[3].id | pmh:oai:europepmc.org:4602081 |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306400806 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Europe PMC (PubMed Central) |
| locations[3].source.host_organization | https://openalex.org/I1303153112 |
| locations[3].source.host_organization_name | European Bioinformatics Institute |
| locations[3].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/5675723 |
| locations[4].id | pmh:oai:pubmedcentral.nih.gov:5675723 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S2764455111 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | PubMed Central |
| locations[4].source.host_organization | https://openalex.org/I1299303238 |
| locations[4].source.host_organization_name | National Institutes of Health |
| locations[4].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[4].license | |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Text |
| locations[4].license_id | |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | |
| locations[4].landing_page_url | http://doi.org/10.1016/j.omtn.2017.10.003 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5009199887 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Xinyun Song |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I20231570 |
| authorships[0].affiliations[0].raw_affiliation_string | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[0].institutions[0].id | https://openalex.org/I20231570 |
| authorships[0].institutions[0].ror | https://ror.org/02v51f717 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I20231570 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Peking University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Xinyun Song |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[1].author.id | https://openalex.org/A5100360045 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-1888-9154 |
| authorships[1].author.display_name | Xiaoxia Wang |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I20231570 |
| authorships[1].affiliations[0].raw_affiliation_string | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[1].institutions[0].id | https://openalex.org/I20231570 |
| authorships[1].institutions[0].ror | https://ror.org/02v51f717 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I20231570 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Peking University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Xiaoxia Wang |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[2].author.id | https://openalex.org/A5082886782 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-7846-4863 |
| authorships[2].author.display_name | Yuan Ma |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I20231570 |
| authorships[2].affiliations[0].raw_affiliation_string | State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China |
| authorships[2].institutions[0].id | https://openalex.org/I20231570 |
| authorships[2].institutions[0].ror | https://ror.org/02v51f717 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I20231570 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Peking University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Yuan Ma |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China |
| authorships[3].author.id | https://openalex.org/A5109378596 |
| authorships[3].author.orcid | https://orcid.org/0009-0009-8636-6778 |
| authorships[3].author.display_name | Zicai Liang |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I20231570 |
| authorships[3].affiliations[0].raw_affiliation_string | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[3].institutions[0].id | https://openalex.org/I20231570 |
| authorships[3].institutions[0].ror | https://ror.org/02v51f717 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I20231570 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Peking University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Zicai Liang |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[4].author.id | https://openalex.org/A5060533134 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-7614-595X |
| authorships[4].author.display_name | Zhenjun Yang |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I20231570 |
| authorships[4].affiliations[0].raw_affiliation_string | State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China |
| authorships[4].institutions[0].id | https://openalex.org/I20231570 |
| authorships[4].institutions[0].ror | https://ror.org/02v51f717 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I20231570 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Peking University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Zhenjun Yang |
| authorships[4].is_corresponding | True |
| authorships[4].raw_affiliation_strings | State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China |
| authorships[5].author.id | https://openalex.org/A5100737320 |
| authorships[5].author.orcid | https://orcid.org/0000-0001-9728-6743 |
| authorships[5].author.display_name | Huiqing Cao |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I20231570 |
| authorships[5].affiliations[0].raw_affiliation_string | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| authorships[5].institutions[0].id | https://openalex.org/I20231570 |
| authorships[5].institutions[0].ror | https://ror.org/02v51f717 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I20231570 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Peking University |
| authorships[5].author_position | last |
| authorships[5].raw_author_name | Huiqing Cao |
| authorships[5].is_corresponding | True |
| authorships[5].raw_affiliation_strings | Laboratory of Nucleic Acid Technology, Institute of Molecular Medicine, Peking University, Beijing 100871, China |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | http://www.cell.com/article/S2162253117302640/pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Site-Specific Modification Using the 2′-Methoxyethyl Group Improves the Specificity and Activity of siRNAs |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10725 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | RNA Interference and Gene Delivery |
| related_works | https://openalex.org/W3140432620, https://openalex.org/W1978057048, https://openalex.org/W2132697617, https://openalex.org/W2047147668, https://openalex.org/W2485236187, https://openalex.org/W2417470032, https://openalex.org/W1985127633, https://openalex.org/W2361323882, https://openalex.org/W1649999227, https://openalex.org/W1540115331 |
| cited_by_count | 47 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 12 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 10 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 8 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 8 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 4 |
| counts_by_year[5].year | 2020 |
| counts_by_year[5].cited_by_count | 3 |
| counts_by_year[6].year | 2019 |
| counts_by_year[6].cited_by_count | 1 |
| counts_by_year[7].year | 2018 |
| counts_by_year[7].cited_by_count | 1 |
| locations_count | 5 |
| best_oa_location.id | doi:10.1016/j.omtn.2017.10.003 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764969478 |
| best_oa_location.source.issn | 2162-2531 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2162-2531 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Molecular Therapy — Nucleic Acids |
| best_oa_location.source.host_organization | https://openalex.org/P4310315673 |
| best_oa_location.source.host_organization_name | Cell Press |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310315673, https://openalex.org/P4310320990 |
| best_oa_location.source.host_organization_lineage_names | Cell Press, Elsevier BV |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | http://www.cell.com/article/S2162253117302640/pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Molecular Therapy - Nucleic Acids |
| best_oa_location.landing_page_url | https://doi.org/10.1016/j.omtn.2017.10.003 |
| primary_location.id | doi:10.1016/j.omtn.2017.10.003 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2764969478 |
| primary_location.source.issn | 2162-2531 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2162-2531 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Molecular Therapy — Nucleic Acids |
| primary_location.source.host_organization | https://openalex.org/P4310315673 |
| primary_location.source.host_organization_name | Cell Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310315673, https://openalex.org/P4310320990 |
| primary_location.source.host_organization_lineage_names | Cell Press, Elsevier BV |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | http://www.cell.com/article/S2162253117302640/pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Molecular Therapy - Nucleic Acids |
| primary_location.landing_page_url | https://doi.org/10.1016/j.omtn.2017.10.003 |
| publication_date | 2017-10-12 |
| publication_year | 2017 |
| referenced_works | https://openalex.org/W1966973232, https://openalex.org/W2102694589, https://openalex.org/W2131246621, https://openalex.org/W2493218919, https://openalex.org/W2339674122, https://openalex.org/W2280833244, https://openalex.org/W2098431098, https://openalex.org/W2017642141, https://openalex.org/W2143313350, https://openalex.org/W1501059295, https://openalex.org/W2530045699, https://openalex.org/W2165366948, https://openalex.org/W2170103998, https://openalex.org/W2009045250, https://openalex.org/W2069721794, https://openalex.org/W2134596861, https://openalex.org/W1988809912, https://openalex.org/W2068635711, https://openalex.org/W2157287222, https://openalex.org/W2156189089, https://openalex.org/W2068984659, https://openalex.org/W2105258749, https://openalex.org/W2156486579, https://openalex.org/W2265533369, https://openalex.org/W2284266226, https://openalex.org/W2043393352, https://openalex.org/W2142327734, https://openalex.org/W2025566170, https://openalex.org/W2168993612, https://openalex.org/W2023246459, https://openalex.org/W2149538815, https://openalex.org/W2034394760, https://openalex.org/W2115558774, https://openalex.org/W2030635137, https://openalex.org/W1995177765 |
| referenced_works_count | 35 |
| abstract_inverted_index | |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5060533134, https://openalex.org/A5100737320 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 6 |
| corresponding_institution_ids | https://openalex.org/I20231570 |
| citation_normalized_percentile.value | 0.65771446 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |