Sorghum Grain Polyphenolic Extracts Demonstrate Neuroprotective Effects Related to Alzheimer’s Disease in Cellular Assays Article Swipe
Nasim Rezaee
,
Eugene Hone
,
Hamid R. Sohrabi
,
Stuart Johnson
,
Liezhou Zhong
,
Prakhar Chatur
,
Stuart Gunzburg
,
Ralph N. Martins
,
Warnakulasuriya Mary Ann Dipika Binosha Fernando
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/foods13111716
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/foods13111716
Sorghum grain contains high levels and a diverse profile of polyphenols (PPs), which are antioxidants known to reduce oxidative stress when consumed in the diet. Oxidative stress leading to amyloid-β (Aβ) aggregation, neurotoxicity, and mitochondrial dysfunction is implicated in the pathogenesis of Alzheimer’s disease (AD). Thus, PPs have gained attention as possible therapeutic agents for combating AD. This study aimed to (a) quantify the phenolic compounds (PP) and antioxidant capacities in extracts from six different varieties of sorghum grain and (b) investigate whether these PP extracts exhibit any protective effects on human neuroblastoma (BE(2)-M17) cells against Aβ- and tau-induced toxicity, Aβ aggregation, mitochondrial dysfunction, and reactive oxygen species (ROS) induced by Aβ and tert-butyl hydroperoxide (TBHP). PP and antioxidant capacity were quantified using chemical assays. Aβ- and tau-induced toxicity was determined using the 3-(4,5-dimenthylthiazol-2-yl)-2,5-dimethyltetrazolium bromide (MTS) assay. The thioflavin T (Th-T) assay assessed anti-Aβ aggregation. The dichlorodihydrofluorescein diacetate (DCFDA) assay determined the levels of general ROS and the MitoSOX assay determined the levels of mitochondrial superoxide. Sorghum varieties Shawaya short black-1 and IS1311C possessed the highest levels of total phenolics, total flavonoids, and antioxidant capacity, and sorghum varieties differed significantly in their profile of individual PPs. All extracts significantly increased cell viability compared to the control (minus extract). Variety QL33 (at 2000 µg sorghum flour equivalents/mL) showed the strongest protective effect with a 28% reduction in Aβ-toxicity cell death. The extracts of all sorghum varieties significantly reduced Aβ aggregation. All extracts except that from variety B923296 demonstrated a significant (p ≤ 0.05) downregulation of Aβ-induced and TBHP-induced ROS and mitochondrial superoxide relative to the control (minus extract) in a dose- and variety-dependent manner. We have demonstrated for the first time that sorghum polyphenolic extracts show promising neuroprotective effects against AD, which indicates the potential of sorghum foods to exert a similar beneficial property in the human diet. However, further analysis in other cellular models and in vivo is needed to confirm these effects.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/foods13111716
- https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265
- OA Status
- gold
- Cited By
- 4
- References
- 83
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4399183802
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4399183802Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/foods13111716Digital Object Identifier
- Title
-
Sorghum Grain Polyphenolic Extracts Demonstrate Neuroprotective Effects Related to Alzheimer’s Disease in Cellular AssaysWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-05-30Full publication date if available
- Authors
-
Nasim Rezaee, Eugene Hone, Hamid R. Sohrabi, Stuart Johnson, Liezhou Zhong, Prakhar Chatur, Stuart Gunzburg, Ralph N. Martins, Warnakulasuriya Mary Ann Dipika Binosha FernandoList of authors in order
- Landing page
-
https://doi.org/10.3390/foods13111716Publisher landing page
- PDF URL
-
https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265Direct OA link when available
- Concepts
-
Oxidative stress, Neuroprotection, Antioxidant, Polyphenol, Sorghum, Reactive oxygen species, Viability assay, Chemistry, Neurotoxicity, Toxicity, Biochemistry, Food science, Pharmacology, Biology, Cell, Ecology, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
4Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4Per-year citation counts (last 5 years)
- References (count)
-
83Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4399183802 |
|---|---|
| doi | https://doi.org/10.3390/foods13111716 |
| ids.doi | https://doi.org/10.3390/foods13111716 |
| ids.openalex | https://openalex.org/W4399183802 |
| fwci | 2.06553939 |
| type | article |
| title | Sorghum Grain Polyphenolic Extracts Demonstrate Neuroprotective Effects Related to Alzheimer’s Disease in Cellular Assays |
| biblio.issue | 11 |
| biblio.volume | 13 |
| biblio.last_page | 1716 |
| biblio.first_page | 1716 |
| topics[0].id | https://openalex.org/T10035 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9976000189781189 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2704 |
| topics[0].subfield.display_name | Biochemistry |
| topics[0].display_name | Phytochemicals and Antioxidant Activities |
| topics[1].id | https://openalex.org/T10086 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9915000200271606 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2737 |
| topics[1].subfield.display_name | Physiology |
| topics[1].display_name | Alzheimer's disease research and treatments |
| topics[2].id | https://openalex.org/T10140 |
| topics[2].field.id | https://openalex.org/fields/29 |
| topics[2].field.display_name | Nursing |
| topics[2].score | 0.9907000064849854 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2916 |
| topics[2].subfield.display_name | Nutrition and Dietetics |
| topics[2].display_name | Food composition and properties |
| is_xpac | False |
| apc_list.value | 2200 |
| apc_list.currency | CHF |
| apc_list.value_usd | 2382 |
| apc_paid.value | 2200 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 2382 |
| concepts[0].id | https://openalex.org/C2776151105 |
| concepts[0].level | 2 |
| concepts[0].score | 0.796202540397644 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q898814 |
| concepts[0].display_name | Oxidative stress |
| concepts[1].id | https://openalex.org/C25498285 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6976525783538818 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1981368 |
| concepts[1].display_name | Neuroprotection |
| concepts[2].id | https://openalex.org/C2778004101 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6961729526519775 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q133948 |
| concepts[2].display_name | Antioxidant |
| concepts[3].id | https://openalex.org/C70899900 |
| concepts[3].level | 3 |
| concepts[3].score | 0.6877299547195435 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q290439 |
| concepts[3].display_name | Polyphenol |
| concepts[4].id | https://openalex.org/C2778157034 |
| concepts[4].level | 2 |
| concepts[4].score | 0.6837162971496582 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q12111 |
| concepts[4].display_name | Sorghum |
| concepts[5].id | https://openalex.org/C48349386 |
| concepts[5].level | 2 |
| concepts[5].score | 0.6725438833236694 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q424361 |
| concepts[5].display_name | Reactive oxygen species |
| concepts[6].id | https://openalex.org/C53227056 |
| concepts[6].level | 3 |
| concepts[6].score | 0.556925356388092 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q189152 |
| concepts[6].display_name | Viability assay |
| concepts[7].id | https://openalex.org/C185592680 |
| concepts[7].level | 0 |
| concepts[7].score | 0.5482462644577026 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[7].display_name | Chemistry |
| concepts[8].id | https://openalex.org/C2779491297 |
| concepts[8].level | 3 |
| concepts[8].score | 0.474601686000824 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q3338704 |
| concepts[8].display_name | Neurotoxicity |
| concepts[9].id | https://openalex.org/C29730261 |
| concepts[9].level | 2 |
| concepts[9].score | 0.46728286147117615 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q274160 |
| concepts[9].display_name | Toxicity |
| concepts[10].id | https://openalex.org/C55493867 |
| concepts[10].level | 1 |
| concepts[10].score | 0.411262571811676 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q7094 |
| concepts[10].display_name | Biochemistry |
| concepts[11].id | https://openalex.org/C31903555 |
| concepts[11].level | 1 |
| concepts[11].score | 0.40775594115257263 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q1637030 |
| concepts[11].display_name | Food science |
| concepts[12].id | https://openalex.org/C98274493 |
| concepts[12].level | 1 |
| concepts[12].score | 0.40270450711250305 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q128406 |
| concepts[12].display_name | Pharmacology |
| concepts[13].id | https://openalex.org/C86803240 |
| concepts[13].level | 0 |
| concepts[13].score | 0.32871565222740173 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[13].display_name | Biology |
| concepts[14].id | https://openalex.org/C1491633281 |
| concepts[14].level | 2 |
| concepts[14].score | 0.1478661298751831 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q7868 |
| concepts[14].display_name | Cell |
| concepts[15].id | https://openalex.org/C18903297 |
| concepts[15].level | 1 |
| concepts[15].score | 0.0 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q7150 |
| concepts[15].display_name | Ecology |
| concepts[16].id | https://openalex.org/C178790620 |
| concepts[16].level | 1 |
| concepts[16].score | 0.0 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q11351 |
| concepts[16].display_name | Organic chemistry |
| keywords[0].id | https://openalex.org/keywords/oxidative-stress |
| keywords[0].score | 0.796202540397644 |
| keywords[0].display_name | Oxidative stress |
| keywords[1].id | https://openalex.org/keywords/neuroprotection |
| keywords[1].score | 0.6976525783538818 |
| keywords[1].display_name | Neuroprotection |
| keywords[2].id | https://openalex.org/keywords/antioxidant |
| keywords[2].score | 0.6961729526519775 |
| keywords[2].display_name | Antioxidant |
| keywords[3].id | https://openalex.org/keywords/polyphenol |
| keywords[3].score | 0.6877299547195435 |
| keywords[3].display_name | Polyphenol |
| keywords[4].id | https://openalex.org/keywords/sorghum |
| keywords[4].score | 0.6837162971496582 |
| keywords[4].display_name | Sorghum |
| keywords[5].id | https://openalex.org/keywords/reactive-oxygen-species |
| keywords[5].score | 0.6725438833236694 |
| keywords[5].display_name | Reactive oxygen species |
| keywords[6].id | https://openalex.org/keywords/viability-assay |
| keywords[6].score | 0.556925356388092 |
| keywords[6].display_name | Viability assay |
| keywords[7].id | https://openalex.org/keywords/chemistry |
| keywords[7].score | 0.5482462644577026 |
| keywords[7].display_name | Chemistry |
| keywords[8].id | https://openalex.org/keywords/neurotoxicity |
| keywords[8].score | 0.474601686000824 |
| keywords[8].display_name | Neurotoxicity |
| keywords[9].id | https://openalex.org/keywords/toxicity |
| keywords[9].score | 0.46728286147117615 |
| keywords[9].display_name | Toxicity |
| keywords[10].id | https://openalex.org/keywords/biochemistry |
| keywords[10].score | 0.411262571811676 |
| keywords[10].display_name | Biochemistry |
| keywords[11].id | https://openalex.org/keywords/food-science |
| keywords[11].score | 0.40775594115257263 |
| keywords[11].display_name | Food science |
| keywords[12].id | https://openalex.org/keywords/pharmacology |
| keywords[12].score | 0.40270450711250305 |
| keywords[12].display_name | Pharmacology |
| keywords[13].id | https://openalex.org/keywords/biology |
| keywords[13].score | 0.32871565222740173 |
| keywords[13].display_name | Biology |
| keywords[14].id | https://openalex.org/keywords/cell |
| keywords[14].score | 0.1478661298751831 |
| keywords[14].display_name | Cell |
| language | en |
| locations[0].id | doi:10.3390/foods13111716 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2737939966 |
| locations[0].source.issn | 2304-8158 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2304-8158 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Foods |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Foods |
| locations[0].landing_page_url | https://doi.org/10.3390/foods13111716 |
| locations[1].id | pmh:oai:ro.ecu.edu.au:ecuworks2022-2026-5173 |
| locations[1].is_oa | True |
| locations[1].source.id | https://openalex.org/S4306400464 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | Research Online (Edith Cowan University) |
| locations[1].source.host_organization | https://openalex.org/I12079687 |
| locations[1].source.host_organization_name | Edith Cowan University |
| locations[1].source.host_organization_lineage | https://openalex.org/I12079687 |
| locations[1].license | cc-by |
| locations[1].pdf_url | |
| locations[1].version | submittedVersion |
| locations[1].raw_type | text |
| locations[1].license_id | https://openalex.org/licenses/cc-by |
| locations[1].is_accepted | False |
| locations[1].is_published | False |
| locations[1].raw_source_name | Research outputs 2022 to 2026 |
| locations[1].landing_page_url | https://ro.ecu.edu.au/ecuworks2022-2026/4172 |
| locations[2].id | pmh:oai:doaj.org/article:8faf11704ce542a795d6f53733b1f38b |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].source.host_organization_lineage | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Foods, Vol 13, Iss 11, p 1716 (2024) |
| locations[2].landing_page_url | https://doaj.org/article/8faf11704ce542a795d6f53733b1f38b |
| locations[3].id | pmh:oai:mdpi.com:/2304-8158/13/11/1716/ |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306400947 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | True |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | MDPI (MDPI AG) |
| locations[3].source.host_organization | https://openalex.org/I4210097602 |
| locations[3].source.host_organization_name | Multidisciplinary Digital Publishing Institute (Switzerland) |
| locations[3].source.host_organization_lineage | https://openalex.org/I4210097602 |
| locations[3].license | cc-by |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/cc-by |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Foods |
| locations[3].landing_page_url | https://dx.doi.org/10.3390/foods13111716 |
| locations[4].id | pmh:oai:pubmedcentral.nih.gov:11171927 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S2764455111 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | PubMed Central |
| locations[4].source.host_organization | https://openalex.org/I1299303238 |
| locations[4].source.host_organization_name | National Institutes of Health |
| locations[4].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[4].license | other-oa |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Text |
| locations[4].license_id | https://openalex.org/licenses/other-oa |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | Foods |
| locations[4].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11171927 |
| indexed_in | crossref, doaj |
| authorships[0].author.id | https://openalex.org/A5080122550 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Nasim Rezaee |
| authorships[0].countries | AU |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I12079687 |
| authorships[0].affiliations[0].raw_affiliation_string | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[0].institutions[0].id | https://openalex.org/I12079687 |
| authorships[0].institutions[0].ror | https://ror.org/05jhnwe22 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I12079687 |
| authorships[0].institutions[0].country_code | AU |
| authorships[0].institutions[0].display_name | Edith Cowan University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Nasim Rezaee |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[1].author.id | https://openalex.org/A5034316552 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-6708-3718 |
| authorships[1].author.display_name | Eugene Hone |
| authorships[1].countries | AU |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I12079687 |
| authorships[1].affiliations[0].raw_affiliation_string | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[1].institutions[0].id | https://openalex.org/I12079687 |
| authorships[1].institutions[0].ror | https://ror.org/05jhnwe22 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I12079687 |
| authorships[1].institutions[0].country_code | AU |
| authorships[1].institutions[0].display_name | Edith Cowan University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Eugene Hone |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[2].author.id | https://openalex.org/A5026336275 |
| authorships[2].author.orcid | https://orcid.org/0000-0001-8017-8682 |
| authorships[2].author.display_name | Hamid R. Sohrabi |
| authorships[2].countries | AU, US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I12079687 |
| authorships[2].affiliations[0].raw_affiliation_string | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I176790772, https://openalex.org/I4210163881 |
| authorships[2].affiliations[1].raw_affiliation_string | Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Murdoch, WA 6150, Australia |
| authorships[2].affiliations[2].institution_ids | https://openalex.org/I99043593 |
| authorships[2].affiliations[2].raw_affiliation_string | Department of Biomedical Sciences, Macquarie University, Sydney, NSW 2109, Australia |
| authorships[2].institutions[0].id | https://openalex.org/I12079687 |
| authorships[2].institutions[0].ror | https://ror.org/05jhnwe22 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I12079687 |
| authorships[2].institutions[0].country_code | AU |
| authorships[2].institutions[0].display_name | Edith Cowan University |
| authorships[2].institutions[1].id | https://openalex.org/I99043593 |
| authorships[2].institutions[1].ror | https://ror.org/01sf06y89 |
| authorships[2].institutions[1].type | education |
| authorships[2].institutions[1].lineage | https://openalex.org/I99043593 |
| authorships[2].institutions[1].country_code | AU |
| authorships[2].institutions[1].display_name | Macquarie University |
| authorships[2].institutions[2].id | https://openalex.org/I176790772 |
| authorships[2].institutions[2].ror | https://ror.org/00r4sry34 |
| authorships[2].institutions[2].type | education |
| authorships[2].institutions[2].lineage | https://openalex.org/I176790772 |
| authorships[2].institutions[2].country_code | AU |
| authorships[2].institutions[2].display_name | Murdoch University |
| authorships[2].institutions[3].id | https://openalex.org/I4210163881 |
| authorships[2].institutions[3].ror | https://ror.org/05k833b90 |
| authorships[2].institutions[3].type | nonprofit |
| authorships[2].institutions[3].lineage | https://openalex.org/I4210163881 |
| authorships[2].institutions[3].country_code | US |
| authorships[2].institutions[3].display_name | Avenir Health |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Hamid Sohrabi |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Centre for Healthy Ageing, Health Futures Institute, Murdoch University, Murdoch, WA 6150, Australia, Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia, Department of Biomedical Sciences, Macquarie University, Sydney, NSW 2109, Australia |
| authorships[3].author.id | https://openalex.org/A5050760897 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-8357-797X |
| authorships[3].author.display_name | Stuart Johnson |
| authorships[3].countries | AU |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I205640436 |
| authorships[3].affiliations[0].raw_affiliation_string | School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Perth, WA 6845, Australia |
| authorships[3].institutions[0].id | https://openalex.org/I205640436 |
| authorships[3].institutions[0].ror | https://ror.org/02n415q13 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I205640436 |
| authorships[3].institutions[0].country_code | AU |
| authorships[3].institutions[0].display_name | Curtin University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Stuart Johnson |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Perth, WA 6845, Australia |
| authorships[4].author.id | https://openalex.org/A5037078416 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-6847-4240 |
| authorships[4].author.display_name | Liezhou Zhong |
| authorships[4].countries | AU |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I205640436 |
| authorships[4].affiliations[0].raw_affiliation_string | School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Perth, WA 6845, Australia |
| authorships[4].institutions[0].id | https://openalex.org/I205640436 |
| authorships[4].institutions[0].ror | https://ror.org/02n415q13 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I205640436 |
| authorships[4].institutions[0].country_code | AU |
| authorships[4].institutions[0].display_name | Curtin University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Leizhou Zhong |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Perth, WA 6845, Australia |
| authorships[5].author.id | https://openalex.org/A5035698530 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Prakhar Chatur |
| authorships[5].countries | AU |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I205640436 |
| authorships[5].affiliations[0].raw_affiliation_string | School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Perth, WA 6845, Australia |
| authorships[5].institutions[0].id | https://openalex.org/I205640436 |
| authorships[5].institutions[0].ror | https://ror.org/02n415q13 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I205640436 |
| authorships[5].institutions[0].country_code | AU |
| authorships[5].institutions[0].display_name | Curtin University |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Prakhar Chatur |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Perth, WA 6845, Australia |
| authorships[6].author.id | https://openalex.org/A5059636644 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Stuart Gunzburg |
| authorships[6].affiliations[0].raw_affiliation_string | CWEK PTY Ltd., Perth, WA 6845, Australia |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Stuart Gunzburg |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | CWEK PTY Ltd., Perth, WA 6845, Australia |
| authorships[7].author.id | https://openalex.org/A5065618928 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-4828-9363 |
| authorships[7].author.display_name | Ralph N. Martins |
| authorships[7].countries | AU |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I99043593 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Biomedical Sciences, Macquarie University, Sydney, NSW 2109, Australia |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I12079687 |
| authorships[7].affiliations[1].raw_affiliation_string | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[7].institutions[0].id | https://openalex.org/I12079687 |
| authorships[7].institutions[0].ror | https://ror.org/05jhnwe22 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I12079687 |
| authorships[7].institutions[0].country_code | AU |
| authorships[7].institutions[0].display_name | Edith Cowan University |
| authorships[7].institutions[1].id | https://openalex.org/I99043593 |
| authorships[7].institutions[1].ror | https://ror.org/01sf06y89 |
| authorships[7].institutions[1].type | education |
| authorships[7].institutions[1].lineage | https://openalex.org/I99043593 |
| authorships[7].institutions[1].country_code | AU |
| authorships[7].institutions[1].display_name | Macquarie University |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Ralph Martins |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia, Department of Biomedical Sciences, Macquarie University, Sydney, NSW 2109, Australia |
| authorships[8].author.id | https://openalex.org/A5082762775 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-8364-7808 |
| authorships[8].author.display_name | Warnakulasuriya Mary Ann Dipika Binosha Fernando |
| authorships[8].countries | AU |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I12079687 |
| authorships[8].affiliations[0].raw_affiliation_string | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| authorships[8].institutions[0].id | https://openalex.org/I12079687 |
| authorships[8].institutions[0].ror | https://ror.org/05jhnwe22 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I12079687 |
| authorships[8].institutions[0].country_code | AU |
| authorships[8].institutions[0].display_name | Edith Cowan University |
| authorships[8].author_position | last |
| authorships[8].raw_author_name | W. Fernando |
| authorships[8].is_corresponding | True |
| authorships[8].raw_affiliation_strings | Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA 6027, Australia |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2024-05-31T00:00:00 |
| display_name | Sorghum Grain Polyphenolic Extracts Demonstrate Neuroprotective Effects Related to Alzheimer’s Disease in Cellular Assays |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10035 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9976000189781189 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2704 |
| primary_topic.subfield.display_name | Biochemistry |
| primary_topic.display_name | Phytochemicals and Antioxidant Activities |
| related_works | https://openalex.org/W2580715149, https://openalex.org/W3211066430, https://openalex.org/W2058245120, https://openalex.org/W2055633927, https://openalex.org/W201266529, https://openalex.org/W2970559029, https://openalex.org/W2365256125, https://openalex.org/W4205231416, https://openalex.org/W2077655479, https://openalex.org/W2050501874 |
| cited_by_count | 4 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 4 |
| locations_count | 5 |
| best_oa_location.id | doi:10.3390/foods13111716 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2737939966 |
| best_oa_location.source.issn | 2304-8158 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2304-8158 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Foods |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Foods |
| best_oa_location.landing_page_url | https://doi.org/10.3390/foods13111716 |
| primary_location.id | doi:10.3390/foods13111716 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2737939966 |
| primary_location.source.issn | 2304-8158 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2304-8158 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Foods |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/2304-8158/13/11/1716/pdf?version=1717051265 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Foods |
| primary_location.landing_page_url | https://doi.org/10.3390/foods13111716 |
| publication_date | 2024-05-30 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W1994676548, https://openalex.org/W2007024645, https://openalex.org/W1993533629, https://openalex.org/W6748870641, https://openalex.org/W1986168235, https://openalex.org/W2803878064, https://openalex.org/W3036920839, https://openalex.org/W1972439404, https://openalex.org/W2076598575, https://openalex.org/W2907170302, https://openalex.org/W2076730654, https://openalex.org/W2084593700, https://openalex.org/W4247088117, https://openalex.org/W2108128042, https://openalex.org/W2913303823, https://openalex.org/W2028687228, https://openalex.org/W2052380265, https://openalex.org/W2084369384, https://openalex.org/W1996463511, https://openalex.org/W2157067671, https://openalex.org/W2001148507, https://openalex.org/W2026564199, https://openalex.org/W2005854408, https://openalex.org/W2008339886, https://openalex.org/W2895893451, https://openalex.org/W2461723517, https://openalex.org/W2314153396, https://openalex.org/W2026382965, https://openalex.org/W2043733949, https://openalex.org/W2311969364, https://openalex.org/W2161229173, https://openalex.org/W1780440403, https://openalex.org/W2906935376, https://openalex.org/W2463434945, https://openalex.org/W611516593, https://openalex.org/W6741726747, https://openalex.org/W6712341624, https://openalex.org/W2038706200, https://openalex.org/W2068448215, https://openalex.org/W2054409358, https://openalex.org/W2093456557, https://openalex.org/W2599534399, https://openalex.org/W6714549194, https://openalex.org/W2904042381, https://openalex.org/W2044349287, https://openalex.org/W1897708277, https://openalex.org/W2086959952, https://openalex.org/W2119971031, https://openalex.org/W2008487250, https://openalex.org/W2020069228, https://openalex.org/W2766388141, https://openalex.org/W1759773337, https://openalex.org/W2762644805, https://openalex.org/W1584531823, https://openalex.org/W1570813833, https://openalex.org/W1735326722, https://openalex.org/W2793937433, https://openalex.org/W1877143754, https://openalex.org/W2046866058, https://openalex.org/W2068242678, https://openalex.org/W2515262002, https://openalex.org/W2112920276, https://openalex.org/W2038183008, https://openalex.org/W2065390758, https://openalex.org/W1747369139, https://openalex.org/W1135802992, https://openalex.org/W2095529706, https://openalex.org/W1987584317, https://openalex.org/W2600117710, https://openalex.org/W1987828385, https://openalex.org/W2792306501, https://openalex.org/W3045330639, https://openalex.org/W3112237618, https://openalex.org/W2082843893, https://openalex.org/W3204888326, https://openalex.org/W6726707849, https://openalex.org/W2154229994, https://openalex.org/W2397680126, https://openalex.org/W2520364132, https://openalex.org/W2790941911, https://openalex.org/W2736702137, https://openalex.org/W2410242694, https://openalex.org/W2050897300 |
| referenced_works_count | 83 |
| abstract_inverted_index.T | 139 |
| abstract_inverted_index.a | 6, 222, 247, 268, 299 |
| abstract_inverted_index.(p | 249 |
| abstract_inverted_index.PP | 84, 116 |
| abstract_inverted_index.We | 273 |
| abstract_inverted_index.as | 50 |
| abstract_inverted_index.by | 110 |
| abstract_inverted_index.in | 22, 38, 70, 190, 225, 267, 303, 310, 315 |
| abstract_inverted_index.is | 36, 317 |
| abstract_inverted_index.of | 9, 41, 76, 153, 163, 177, 193, 231, 253, 294 |
| abstract_inverted_index.on | 90 |
| abstract_inverted_index.to | 16, 28, 60, 203, 262, 297, 319 |
| abstract_inverted_index.(a) | 61 |
| abstract_inverted_index.(at | 210 |
| abstract_inverted_index.(b) | 80 |
| abstract_inverted_index.28% | 223 |
| abstract_inverted_index.AD, | 289 |
| abstract_inverted_index.AD. | 56 |
| abstract_inverted_index.All | 196, 239 |
| abstract_inverted_index.Aβ | 100, 111, 237 |
| abstract_inverted_index.PPs | 46 |
| abstract_inverted_index.ROS | 155, 257 |
| abstract_inverted_index.The | 137, 145, 229 |
| abstract_inverted_index.all | 232 |
| abstract_inverted_index.and | 5, 33, 67, 79, 97, 104, 112, 117, 126, 156, 171, 182, 185, 255, 258, 270, 314 |
| abstract_inverted_index.any | 87 |
| abstract_inverted_index.are | 13 |
| abstract_inverted_index.for | 54, 276 |
| abstract_inverted_index.six | 73 |
| abstract_inverted_index.the | 23, 39, 63, 132, 151, 157, 161, 174, 204, 217, 263, 277, 292, 304 |
| abstract_inverted_index.was | 129 |
| abstract_inverted_index.µg | 212 |
| abstract_inverted_index.≤ | 250 |
| abstract_inverted_index.(PP) | 66 |
| abstract_inverted_index.2000 | 211 |
| abstract_inverted_index.Aβ- | 96, 125 |
| abstract_inverted_index.PPs. | 195 |
| abstract_inverted_index.QL33 | 209 |
| abstract_inverted_index.This | 57 |
| abstract_inverted_index.cell | 200, 227 |
| abstract_inverted_index.from | 72, 243 |
| abstract_inverted_index.have | 47, 274 |
| abstract_inverted_index.high | 3 |
| abstract_inverted_index.show | 284 |
| abstract_inverted_index.that | 242, 280 |
| abstract_inverted_index.time | 279 |
| abstract_inverted_index.vivo | 316 |
| abstract_inverted_index.were | 120 |
| abstract_inverted_index.when | 20 |
| abstract_inverted_index.with | 221 |
| abstract_inverted_index.(AD). | 44 |
| abstract_inverted_index.(Aβ) | 30 |
| abstract_inverted_index.(MTS) | 135 |
| abstract_inverted_index.(ROS) | 108 |
| abstract_inverted_index.0.05) | 251 |
| abstract_inverted_index.Thus, | 45 |
| abstract_inverted_index.aimed | 59 |
| abstract_inverted_index.assay | 141, 149, 159 |
| abstract_inverted_index.cells | 94 |
| abstract_inverted_index.diet. | 24, 306 |
| abstract_inverted_index.dose- | 269 |
| abstract_inverted_index.exert | 298 |
| abstract_inverted_index.first | 278 |
| abstract_inverted_index.flour | 214 |
| abstract_inverted_index.foods | 296 |
| abstract_inverted_index.grain | 1, 78 |
| abstract_inverted_index.human | 91, 305 |
| abstract_inverted_index.known | 15 |
| abstract_inverted_index.other | 311 |
| abstract_inverted_index.short | 169 |
| abstract_inverted_index.study | 58 |
| abstract_inverted_index.their | 191 |
| abstract_inverted_index.these | 83, 321 |
| abstract_inverted_index.total | 178, 180 |
| abstract_inverted_index.using | 122, 131 |
| abstract_inverted_index.which | 12, 290 |
| abstract_inverted_index.(PPs), | 11 |
| abstract_inverted_index.(Th-T) | 140 |
| abstract_inverted_index.(minus | 206, 265 |
| abstract_inverted_index.agents | 53 |
| abstract_inverted_index.assay. | 136 |
| abstract_inverted_index.death. | 228 |
| abstract_inverted_index.effect | 220 |
| abstract_inverted_index.except | 241 |
| abstract_inverted_index.gained | 48 |
| abstract_inverted_index.levels | 4, 152, 162, 176 |
| abstract_inverted_index.models | 313 |
| abstract_inverted_index.needed | 318 |
| abstract_inverted_index.oxygen | 106 |
| abstract_inverted_index.reduce | 17 |
| abstract_inverted_index.showed | 216 |
| abstract_inverted_index.stress | 19, 26 |
| abstract_inverted_index.(DCFDA) | 148 |
| abstract_inverted_index.(TBHP). | 115 |
| abstract_inverted_index.B923296 | 245 |
| abstract_inverted_index.IS1311C | 172 |
| abstract_inverted_index.MitoSOX | 158 |
| abstract_inverted_index.Shawaya | 168 |
| abstract_inverted_index.Sorghum | 0, 166 |
| abstract_inverted_index.Variety | 208 |
| abstract_inverted_index.against | 95, 288 |
| abstract_inverted_index.assays. | 124 |
| abstract_inverted_index.black-1 | 170 |
| abstract_inverted_index.bromide | 134 |
| abstract_inverted_index.confirm | 320 |
| abstract_inverted_index.control | 205, 264 |
| abstract_inverted_index.disease | 43 |
| abstract_inverted_index.diverse | 7 |
| abstract_inverted_index.effects | 89, 287 |
| abstract_inverted_index.exhibit | 86 |
| abstract_inverted_index.further | 308 |
| abstract_inverted_index.general | 154 |
| abstract_inverted_index.highest | 175 |
| abstract_inverted_index.induced | 109 |
| abstract_inverted_index.leading | 27 |
| abstract_inverted_index.manner. | 272 |
| abstract_inverted_index.profile | 8, 192 |
| abstract_inverted_index.reduced | 236 |
| abstract_inverted_index.similar | 300 |
| abstract_inverted_index.sorghum | 77, 186, 213, 233, 281, 295 |
| abstract_inverted_index.species | 107 |
| abstract_inverted_index.variety | 244 |
| abstract_inverted_index.whether | 82 |
| abstract_inverted_index.However, | 307 |
| abstract_inverted_index.analysis | 309 |
| abstract_inverted_index.anti-Aβ | 143 |
| abstract_inverted_index.assessed | 142 |
| abstract_inverted_index.capacity | 119 |
| abstract_inverted_index.cellular | 312 |
| abstract_inverted_index.chemical | 123 |
| abstract_inverted_index.compared | 202 |
| abstract_inverted_index.consumed | 21 |
| abstract_inverted_index.contains | 2 |
| abstract_inverted_index.differed | 188 |
| abstract_inverted_index.effects. | 322 |
| abstract_inverted_index.extract) | 266 |
| abstract_inverted_index.extracts | 71, 85, 197, 230, 240, 283 |
| abstract_inverted_index.phenolic | 64 |
| abstract_inverted_index.possible | 51 |
| abstract_inverted_index.property | 302 |
| abstract_inverted_index.quantify | 62 |
| abstract_inverted_index.reactive | 105 |
| abstract_inverted_index.relative | 261 |
| abstract_inverted_index.toxicity | 128 |
| abstract_inverted_index.Oxidative | 25 |
| abstract_inverted_index.attention | 49 |
| abstract_inverted_index.capacity, | 184 |
| abstract_inverted_index.combating | 55 |
| abstract_inverted_index.compounds | 65 |
| abstract_inverted_index.diacetate | 147 |
| abstract_inverted_index.different | 74 |
| abstract_inverted_index.extract). | 207 |
| abstract_inverted_index.increased | 199 |
| abstract_inverted_index.indicates | 291 |
| abstract_inverted_index.oxidative | 18 |
| abstract_inverted_index.possessed | 173 |
| abstract_inverted_index.potential | 293 |
| abstract_inverted_index.promising | 285 |
| abstract_inverted_index.reduction | 224 |
| abstract_inverted_index.strongest | 218 |
| abstract_inverted_index.toxicity, | 99 |
| abstract_inverted_index.varieties | 75, 167, 187, 234 |
| abstract_inverted_index.viability | 201 |
| abstract_inverted_index.amyloid-β | 29 |
| abstract_inverted_index.beneficial | 301 |
| abstract_inverted_index.capacities | 69 |
| abstract_inverted_index.determined | 130, 150, 160 |
| abstract_inverted_index.implicated | 37 |
| abstract_inverted_index.individual | 194 |
| abstract_inverted_index.phenolics, | 179 |
| abstract_inverted_index.protective | 88, 219 |
| abstract_inverted_index.quantified | 121 |
| abstract_inverted_index.superoxide | 260 |
| abstract_inverted_index.tert-butyl | 113 |
| abstract_inverted_index.thioflavin | 138 |
| abstract_inverted_index.(BE(2)-M17) | 93 |
| abstract_inverted_index.Aβ-induced | 254 |
| abstract_inverted_index.antioxidant | 68, 118, 183 |
| abstract_inverted_index.dysfunction | 35 |
| abstract_inverted_index.flavonoids, | 181 |
| abstract_inverted_index.investigate | 81 |
| abstract_inverted_index.polyphenols | 10 |
| abstract_inverted_index.significant | 248 |
| abstract_inverted_index.superoxide. | 165 |
| abstract_inverted_index.tau-induced | 98, 127 |
| abstract_inverted_index.therapeutic | 52 |
| abstract_inverted_index.Aβ-toxicity | 226 |
| abstract_inverted_index.TBHP-induced | 256 |
| abstract_inverted_index.aggregation, | 31, 101 |
| abstract_inverted_index.aggregation. | 144, 238 |
| abstract_inverted_index.antioxidants | 14 |
| abstract_inverted_index.demonstrated | 246, 275 |
| abstract_inverted_index.dysfunction, | 103 |
| abstract_inverted_index.pathogenesis | 40 |
| abstract_inverted_index.polyphenolic | 282 |
| abstract_inverted_index.Alzheimer’s | 42 |
| abstract_inverted_index.hydroperoxide | 114 |
| abstract_inverted_index.mitochondrial | 34, 102, 164, 259 |
| abstract_inverted_index.neuroblastoma | 92 |
| abstract_inverted_index.significantly | 189, 198, 235 |
| abstract_inverted_index.downregulation | 252 |
| abstract_inverted_index.neurotoxicity, | 32 |
| abstract_inverted_index.equivalents/mL) | 215 |
| abstract_inverted_index.neuroprotective | 286 |
| abstract_inverted_index.variety-dependent | 271 |
| abstract_inverted_index.dichlorodihydrofluorescein | 146 |
| abstract_inverted_index.3-(4,5-dimenthylthiazol-2-yl)-2,5-dimethyltetrazolium | 133 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 97 |
| corresponding_author_ids | https://openalex.org/A5082762775 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 9 |
| corresponding_institution_ids | https://openalex.org/I12079687 |
| citation_normalized_percentile.value | 0.74271781 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |