Spectrum of Orbito-ocular Tumour in India: Histopathological and Immunohistochemical Study Article Swipe

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Mousumi Sharm , Pooja Jaiswal , Nausheen S Khan ·

YOU? · · 2022 · Open Access · · DOI: https://doi.org/10.7860/njlm/2022/53617.2645

Introduction: Orbito-ocular tumours are an important cause of morbidity and mortality. Their incidence is low but requires immediate diagnosis and treatment. There are limited research studies on histopathological and immunohistochemical studies of ocular tumour from India and these studies may provide valuable information and aid in accurate diagnosis and management. Aim: To elucidate distribution of age, sex, location of tumour, histopathological, immunohistochemical findings and any other relevant information with respect to orbito-ocular tumours. Materials and Methods: A retrospective observational analysis was conducted over a period of five years from March 2008 to February 2013, in the Department of Pathology in a tertiary care center, Assam, India. Hospital records of 55 patient with malignant ocular tumours were collected, reviewed and statistically analysed. Results: In the present study, a total of 55 cases were included. Out of which, two cases were inconclusive due to inadequate material. Remaining, 53 cases included both intraocular and orbital malignant tumours. Tumours were found slightly more in males (34 cases) compared to females (19) with a ratio of 1.8 to 1. Squamous Cell Carcinoma (SCC) comprised the maximum number (16 cases) followed by Retinoblastoma (RB) in 15 cases and melanoma in 11 cases. In children most common malignancy was RB followed by rhadomyosarcoma (RMS). Conclusion: In this study it was found that SCC was the most common malignant tumour in adults whereas RB was the most common tumour in children.

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Medicine Malignancy Incidence (geometry) Retrospective cohort study Retinoblastoma Immunohistochemistry Basal cell Pathology Histopathology Dermatology Biology Optics Gene Physics Biochemistry

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Type: article
Language: en
Landing Page: https://doi.org/10.7860/njlm/2022/53617.2645
PDF: http://www.njlm.net/articles/PDF/2645/53617_CE[Ra1]_F[SH]_PF1(SG_SHU)_redo_PFA(SHU)_PB(SG_SHU)_PN(SHU).pdf
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Cited By: 1
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DOI: https://doi.org/10.7860/njlm/2022/53617.2645

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Title: Spectrum of Orbito-ocular Tumour in India: Histopathological and Immunohistochemical Study

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Language: en

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Publication year: 2022

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Publication date: 2022-01-01

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Authors: Mousumi Sharm, Pooja Jaiswal, Nausheen S Khan

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Concepts: Medicine, Malignancy, Incidence (geometry), Retrospective cohort study, Retinoblastoma, Immunohistochemistry, Basal cell, Pathology, Histopathology, Dermatology, Biology, Optics, Gene, Physics, Biochemistry

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abstract_inverted_index.males	160
abstract_inverted_index.other	65
abstract_inverted_index.ratio	169
abstract_inverted_index.study	210
abstract_inverted_index.these	37
abstract_inverted_index.total	127
abstract_inverted_index.years	87
abstract_inverted_index.(RMS).	206
abstract_inverted_index.Assam,	104
abstract_inverted_index.India.	105
abstract_inverted_index.adults	223
abstract_inverted_index.cases)	162, 183
abstract_inverted_index.cases.	195
abstract_inverted_index.common	199, 219, 229
abstract_inverted_index.number	181
abstract_inverted_index.ocular	32, 113
abstract_inverted_index.period	84
abstract_inverted_index.study,	125
abstract_inverted_index.tumour	33, 221, 230
abstract_inverted_index.which,	135
abstract_inverted_index.Tumours	154
abstract_inverted_index.center,	103
abstract_inverted_index.females	165
abstract_inverted_index.limited	23
abstract_inverted_index.maximum	180
abstract_inverted_index.orbital	151
abstract_inverted_index.patient	110
abstract_inverted_index.present	124
abstract_inverted_index.provide	40
abstract_inverted_index.records	107
abstract_inverted_index.respect	69
abstract_inverted_index.studies	25, 30, 38
abstract_inverted_index.tumour,	59
abstract_inverted_index.tumours	2, 114
abstract_inverted_index.whereas	224
abstract_inverted_index.February	92
abstract_inverted_index.Hospital	106
abstract_inverted_index.Methods:	75
abstract_inverted_index.Results:	121
abstract_inverted_index.Squamous	174
abstract_inverted_index.accurate	46
abstract_inverted_index.analysis	79
abstract_inverted_index.children	197
abstract_inverted_index.compared	163
abstract_inverted_index.findings	62
abstract_inverted_index.followed	184, 203
abstract_inverted_index.included	147
abstract_inverted_index.location	57
abstract_inverted_index.melanoma	192
abstract_inverted_index.relevant	66
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abstract_inverted_index.research	24
abstract_inverted_index.reviewed	117
abstract_inverted_index.slightly	157
abstract_inverted_index.tertiary	101
abstract_inverted_index.tumours.	72, 153
abstract_inverted_index.valuable	41
abstract_inverted_index.Carcinoma	176
abstract_inverted_index.Materials	73
abstract_inverted_index.Pathology	98
abstract_inverted_index.analysed.	120
abstract_inverted_index.children.	232
abstract_inverted_index.comprised	178
abstract_inverted_index.conducted	81
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abstract_inverted_index.elucidate	52
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abstract_inverted_index.important	5
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abstract_inverted_index.included.	132
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abstract_inverted_index.Department	96
abstract_inverted_index.Remaining,	144
abstract_inverted_index.collected,	116
abstract_inverted_index.inadequate	142
abstract_inverted_index.malignancy	200
abstract_inverted_index.mortality.	10
abstract_inverted_index.treatment.	20
abstract_inverted_index.Conclusion:	207
abstract_inverted_index.information	42, 67
abstract_inverted_index.intraocular	149
abstract_inverted_index.management.	49
abstract_inverted_index.distribution	53
abstract_inverted_index.inconclusive	139
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abstract_inverted_index.orbito-ocular	71
abstract_inverted_index.retrospective	77
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abstract_inverted_index.Retinoblastoma	186
abstract_inverted_index.rhadomyosarcoma	205
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abstract_inverted_index.histopathological,	60
abstract_inverted_index.immunohistochemical	29, 61
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countries_distinct_count	1
institutions_distinct_count	3
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