Split Face Randomized, Evaluator Blinded Study on the Effect of Multiple Subcisions on Rolling Acne Scars Article Swipe
Brian Chen
,
Misha Haq
,
S. Melissa
,
Areeba Ahmed
,
Victoria Shi
,
Eric Koza
,
Joaquin C. Brieva
,
Simon Yoo
,
Jennifer Lucas
,
Murad Alam
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-4344878/v1
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-4344878/v1
Acne scarring results from a common inflammatory condition present in many people. These scars can have an impact on quality of life by influencing self-esteem and social acceptance. Current acne scarring treatments, such as chemical peels and laser treatments, often have limited success due to their time-consuming nature and the variability of acne scar types. The subcision technique has shown promise for the treatment of rolling acne scars. There are few studies to date that examine the effects of multiple subcision treatments on rolling acne scars. We evaluated whether the use of multiple subcision treatments improved the appearance of rolling acne scars compared to no treatment. Five patients with rolling acne scars on both sides of their face who met inclusion and exclusion criteria were enrolled in the study. One side of the face was randomized to receive treatment, while the contralateral side of the face received no treatment. Subjects underwent five sequential subcision treatments, spaced 4 weeks apart, with two follow-up visits at weeks 20 and 36 from the 1st treatment. Photographs were taken before and after the initial treatment visit and at each subsequent visit. Acne scar appearance was evaluated by the subject, a blinded live rater, and two double-blinded dermatologist raters. Evaluations of treatment outcomes involved overall acne scar appearance on a 5-point scale, acne scar improvement on a percentage scale, a modified quantitative global scarring grading system, and potential treatment side effects. There was a greater decrease in global scarring scores in the multiple subcision side compared to the control side. There was a greater difference in the average acne scar appearance scores between the Week 36 follow-up visit and baseline for the multiple subcision side compared to that of the control side. Fifty percent of patients reported being more satisfied with the treatment side compared to the control side in regard to overall improvement. The study results suggest that multiple subcision treatments may improve the appearance of rolling acne scars compared to no treatment.
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-4344878/v1
- https://www.researchsquare.com/article/rs-4344878/latest.pdf
- OA Status
- green
- References
- 16
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4396776400
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4396776400Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.21203/rs.3.rs-4344878/v1Digital Object Identifier
- Title
-
Split Face Randomized, Evaluator Blinded Study on the Effect of Multiple Subcisions on Rolling Acne ScarsWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-05-09Full publication date if available
- Authors
-
Brian Chen, Misha Haq, S. Melissa, Areeba Ahmed, Victoria Shi, Eric Koza, Joaquin C. Brieva, Simon Yoo, Jennifer Lucas, Murad AlamList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.3.rs-4344878/v1Publisher landing page
- PDF URL
-
https://www.researchsquare.com/article/rs-4344878/latest.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.researchsquare.com/article/rs-4344878/latest.pdfDirect OA link when available
- Concepts
-
Acne scars, Scars, Acne, Face (sociological concept), Dermatology, Medicine, Computer science, Surgery, Sociology, Social scienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
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16Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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