Standard-Dose Intradermal Influenza Vaccine Elicits Cellular Immune Responses Similar to Those of Intramuscular Vaccine in Men With and Those Without HIV Infection Article Swipe
Samuel Amoah
,
Margarita Mishina
,
Prabda Praphasiri
,
Weiping Cao
,
Jin Hyang Kim
,
Justine S. Liepkalns
,
Zhu Guo
,
P.J. Carney
,
Jessie Chang
,
Stefan Fernandez
,
Shikha Garg
,
Lauren Beacham
,
Timothy H. Holtz
,
Marcel E. Curlin
,
Fatimah S. Dawood
,
Sonja J. Olsen
,
Shivaprakash Gangappa
,
James Stevens
,
Suryaprakash Sambhara
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1093/infdis/jiz205
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1093/infdis/jiz205
Background Human immunodeficiency virus (HIV)–infected persons are at a higher risk of severe influenza. Although we have shown that a standard-dose intradermal influenza vaccine versus a standard-dose intramuscular influenza vaccine does not result in differences in hemagglutination-inhibition titers in this population, a comprehensive examination of cell-mediated immune responses remains lacking. Methods Serological, antigen-specific B-cell, and interleukin 2–, interferon γ–, and tumor necrosis factor α–secreting T-cell responses were assessed in 79 HIV-infected men and 79 HIV-uninfected men. Results The route of vaccination did not affect the immunoglobulin A and immunoglobulin G (IgG) plasmablast or memory B-cell response, although these were severely impaired in the group with a CD4+ T-cell count of <200 cells/μL. The frequencies of IgG memory B cells measured on day 28 after vaccination were highest in the HIV-uninfected group, followed by the group with a CD4+ T-cell count of ≥200 cells/μL and the group with a CD4+ T-cell count of <200 cells/μL. The route of vaccination did not affect the CD4+ or CD8+ T-cell responses measured at various times after vaccination. Conclusions The route of vaccination had no effect on antibody responses, antibody avidity, T-cell responses, or B-cell responses in HIV-infected or HIV-uninfected subjects. With the serological and cellular immune responses to influenza vaccination being impaired in HIV-infected individuals with a CD4+ T-cell count of <200 cells/μL, passive immunization strategies need to be explored to protect this population. Clinical trials registration NCT01538940.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/infdis/jiz205
- https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdf
- OA Status
- bronze
- Cited By
- 7
- References
- 29
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2942901252
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2942901252Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/infdis/jiz205Digital Object Identifier
- Title
-
Standard-Dose Intradermal Influenza Vaccine Elicits Cellular Immune Responses Similar to Those of Intramuscular Vaccine in Men With and Those Without HIV InfectionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-04-24Full publication date if available
- Authors
-
Samuel Amoah, Margarita Mishina, Prabda Praphasiri, Weiping Cao, Jin Hyang Kim, Justine S. Liepkalns, Zhu Guo, P.J. Carney, Jessie Chang, Stefan Fernandez, Shikha Garg, Lauren Beacham, Timothy H. Holtz, Marcel E. Curlin, Fatimah S. Dawood, Sonja J. Olsen, Shivaprakash Gangappa, James Stevens, Suryaprakash SambharaList of authors in order
- Landing page
-
https://doi.org/10.1093/infdis/jiz205Publisher landing page
- PDF URL
-
https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdfDirect OA link when available
- Concepts
-
Immunology, Influenza vaccine, Immune system, Medicine, Virology, Human immunodeficiency virus (HIV), Intramuscular injection, HIV vaccine, AIDS Vaccines, Vaccination, Vaccine trial, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
7Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 1, 2023: 2, 2022: 2, 2021: 1, 2020: 1Per-year citation counts (last 5 years)
- References (count)
-
29Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2942901252 |
|---|---|
| doi | https://doi.org/10.1093/infdis/jiz205 |
| ids.doi | https://doi.org/10.1093/infdis/jiz205 |
| ids.mag | 2942901252 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/31045222 |
| ids.openalex | https://openalex.org/W2942901252 |
| fwci | 0.78509925 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000328 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Adult |
| mesh[1].qualifier_ui | Q000276 |
| mesh[1].descriptor_ui | D000914 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | immunology |
| mesh[1].descriptor_name | Antibodies, Viral |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D000917 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Antibody Formation |
| mesh[3].qualifier_ui | Q000276 |
| mesh[3].descriptor_ui | D001402 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | immunology |
| mesh[3].descriptor_name | B-Lymphocytes |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D018791 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | CD4 Lymphocyte Count |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D015496 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | CD4-Positive T-Lymphocytes |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D018414 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[7].qualifier_ui | Q000150 |
| mesh[7].descriptor_ui | D015658 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | complications |
| mesh[7].descriptor_name | HIV Infections |
| mesh[8].qualifier_ui | Q000276 |
| mesh[8].descriptor_ui | D015658 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | immunology |
| mesh[8].descriptor_name | HIV Infections |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D006385 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Hemagglutination Inhibition Tests |
| mesh[10].qualifier_ui | Q000276 |
| mesh[10].descriptor_ui | D019267 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | immunology |
| mesh[10].descriptor_name | Hemagglutinin Glycoproteins, Influenza Virus |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D006801 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Humans |
| mesh[12].qualifier_ui | Q000276 |
| mesh[12].descriptor_ui | D007111 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | immunology |
| mesh[12].descriptor_name | Immunity, Cellular |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D007070 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Immunoglobulin A |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D007074 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Immunoglobulin G |
| mesh[15].qualifier_ui | Q000276 |
| mesh[15].descriptor_ui | D053118 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | immunology |
| mesh[15].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[16].qualifier_ui | Q000008 |
| mesh[16].descriptor_ui | D007252 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | administration & dosage |
| mesh[16].descriptor_name | Influenza Vaccines |
| mesh[17].qualifier_ui | Q000276 |
| mesh[17].descriptor_ui | D007252 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | immunology |
| mesh[17].descriptor_name | Influenza Vaccines |
| mesh[18].qualifier_ui | Q000592 |
| mesh[18].descriptor_ui | D007252 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | standards |
| mesh[18].descriptor_name | Influenza Vaccines |
| mesh[19].qualifier_ui | Q000517 |
| mesh[19].descriptor_ui | D007251 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | prevention & control |
| mesh[19].descriptor_name | Influenza, Human |
| mesh[20].qualifier_ui | Q000378 |
| mesh[20].descriptor_ui | D007371 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | metabolism |
| mesh[20].descriptor_name | Interferon-gamma |
| mesh[21].qualifier_ui | Q000378 |
| mesh[21].descriptor_ui | D007376 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | metabolism |
| mesh[21].descriptor_name | Interleukin-2 |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D008297 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Male |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D008875 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Middle Aged |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D013785 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Thailand |
| mesh[25].qualifier_ui | Q000378 |
| mesh[25].descriptor_ui | D014409 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | metabolism |
| mesh[25].descriptor_name | Tumor Necrosis Factor-alpha |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D014611 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Vaccination |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D000328 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Adult |
| mesh[28].qualifier_ui | Q000276 |
| mesh[28].descriptor_ui | D000914 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | immunology |
| mesh[28].descriptor_name | Antibodies, Viral |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D000917 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Antibody Formation |
| mesh[30].qualifier_ui | Q000276 |
| mesh[30].descriptor_ui | D001402 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | immunology |
| mesh[30].descriptor_name | B-Lymphocytes |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D018791 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | CD4 Lymphocyte Count |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D015496 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | CD4-Positive T-Lymphocytes |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D018414 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[34].qualifier_ui | Q000150 |
| mesh[34].descriptor_ui | D015658 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | complications |
| mesh[34].descriptor_name | HIV Infections |
| mesh[35].qualifier_ui | Q000276 |
| mesh[35].descriptor_ui | D015658 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | immunology |
| mesh[35].descriptor_name | HIV Infections |
| mesh[36].qualifier_ui | |
| mesh[36].descriptor_ui | D006385 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | |
| mesh[36].descriptor_name | Hemagglutination Inhibition Tests |
| mesh[37].qualifier_ui | Q000276 |
| mesh[37].descriptor_ui | D019267 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | immunology |
| mesh[37].descriptor_name | Hemagglutinin Glycoproteins, Influenza Virus |
| mesh[38].qualifier_ui | |
| mesh[38].descriptor_ui | D006801 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | |
| mesh[38].descriptor_name | Humans |
| mesh[39].qualifier_ui | Q000276 |
| mesh[39].descriptor_ui | D007111 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | immunology |
| mesh[39].descriptor_name | Immunity, Cellular |
| mesh[40].qualifier_ui | |
| mesh[40].descriptor_ui | D007070 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | |
| mesh[40].descriptor_name | Immunoglobulin A |
| mesh[41].qualifier_ui | |
| mesh[41].descriptor_ui | D007074 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | |
| mesh[41].descriptor_name | Immunoglobulin G |
| mesh[42].qualifier_ui | Q000276 |
| mesh[42].descriptor_ui | D053118 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | immunology |
| mesh[42].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[43].qualifier_ui | Q000008 |
| mesh[43].descriptor_ui | D007252 |
| mesh[43].is_major_topic | False |
| mesh[43].qualifier_name | administration & dosage |
| mesh[43].descriptor_name | Influenza Vaccines |
| mesh[44].qualifier_ui | Q000276 |
| mesh[44].descriptor_ui | D007252 |
| mesh[44].is_major_topic | False |
| mesh[44].qualifier_name | immunology |
| mesh[44].descriptor_name | Influenza Vaccines |
| mesh[45].qualifier_ui | Q000592 |
| mesh[45].descriptor_ui | D007252 |
| mesh[45].is_major_topic | False |
| mesh[45].qualifier_name | standards |
| mesh[45].descriptor_name | Influenza Vaccines |
| mesh[46].qualifier_ui | Q000517 |
| mesh[46].descriptor_ui | D007251 |
| mesh[46].is_major_topic | False |
| mesh[46].qualifier_name | prevention & control |
| mesh[46].descriptor_name | Influenza, Human |
| mesh[47].qualifier_ui | Q000378 |
| mesh[47].descriptor_ui | D007371 |
| mesh[47].is_major_topic | False |
| mesh[47].qualifier_name | metabolism |
| mesh[47].descriptor_name | Interferon-gamma |
| mesh[48].qualifier_ui | Q000378 |
| mesh[48].descriptor_ui | D007376 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | metabolism |
| mesh[48].descriptor_name | Interleukin-2 |
| mesh[49].qualifier_ui | |
| mesh[49].descriptor_ui | D008297 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | |
| mesh[49].descriptor_name | Male |
| type | article |
| title | Standard-Dose Intradermal Influenza Vaccine Elicits Cellular Immune Responses Similar to Those of Intramuscular Vaccine in Men With and Those Without HIV Infection |
| awards[0].id | https://openalex.org/G5004874716 |
| awards[0].funder_id | https://openalex.org/F4320332162 |
| awards[0].funder_award_id | 5U01GH000152 |
| awards[0].funder_display_name | Centers for Disease Control and Prevention |
| biblio.issue | 5 |
| biblio.volume | 220 |
| biblio.last_page | 751 |
| biblio.first_page | 743 |
| grants[0].funder | https://openalex.org/F4320332162 |
| grants[0].award_id | 5U01GH000152 |
| grants[0].funder_display_name | Centers for Disease Control and Prevention |
| topics[0].id | https://openalex.org/T10167 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2713 |
| topics[0].subfield.display_name | Epidemiology |
| topics[0].display_name | Influenza Virus Research Studies |
| topics[1].id | https://openalex.org/T12576 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9973000288009644 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | vaccines and immunoinformatics approaches |
| topics[2].id | https://openalex.org/T10371 |
| topics[2].field.id | https://openalex.org/fields/24 |
| topics[2].field.display_name | Immunology and Microbiology |
| topics[2].score | 0.9965999722480774 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2403 |
| topics[2].subfield.display_name | Immunology |
| topics[2].display_name | Immune Response and Inflammation |
| funders[0].id | https://openalex.org/F4320332162 |
| funders[0].ror | https://ror.org/042twtr12 |
| funders[0].display_name | Centers for Disease Control and Prevention |
| is_xpac | False |
| apc_list.value | 4320 |
| apc_list.currency | USD |
| apc_list.value_usd | 4320 |
| apc_paid | |
| concepts[0].id | https://openalex.org/C203014093 |
| concepts[0].level | 1 |
| concepts[0].score | 0.6992197036743164 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[0].display_name | Immunology |
| concepts[1].id | https://openalex.org/C2780689484 |
| concepts[1].level | 3 |
| concepts[1].score | 0.6737121939659119 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q383260 |
| concepts[1].display_name | Influenza vaccine |
| concepts[2].id | https://openalex.org/C8891405 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6265803575515747 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q1059 |
| concepts[2].display_name | Immune system |
| concepts[3].id | https://openalex.org/C71924100 |
| concepts[3].level | 0 |
| concepts[3].score | 0.6228050589561462 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[3].display_name | Medicine |
| concepts[4].id | https://openalex.org/C159047783 |
| concepts[4].level | 1 |
| concepts[4].score | 0.57911217212677 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q7215 |
| concepts[4].display_name | Virology |
| concepts[5].id | https://openalex.org/C3013748606 |
| concepts[5].level | 2 |
| concepts[5].score | 0.4857078492641449 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q15787 |
| concepts[5].display_name | Human immunodeficiency virus (HIV) |
| concepts[6].id | https://openalex.org/C2776291583 |
| concepts[6].level | 2 |
| concepts[6].score | 0.4568432569503784 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q432083 |
| concepts[6].display_name | Intramuscular injection |
| concepts[7].id | https://openalex.org/C2780195530 |
| concepts[7].level | 4 |
| concepts[7].score | 0.42378777265548706 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1479804 |
| concepts[7].display_name | HIV vaccine |
| concepts[8].id | https://openalex.org/C2909828532 |
| concepts[8].level | 4 |
| concepts[8].score | 0.4170820415019989 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q1479804 |
| concepts[8].display_name | AIDS Vaccines |
| concepts[9].id | https://openalex.org/C22070199 |
| concepts[9].level | 2 |
| concepts[9].score | 0.297446608543396 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q192995 |
| concepts[9].display_name | Vaccination |
| concepts[10].id | https://openalex.org/C2778190748 |
| concepts[10].level | 3 |
| concepts[10].score | 0.16149449348449707 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q7907956 |
| concepts[10].display_name | Vaccine trial |
| concepts[11].id | https://openalex.org/C126322002 |
| concepts[11].level | 1 |
| concepts[11].score | 0.08173355460166931 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[11].display_name | Internal medicine |
| keywords[0].id | https://openalex.org/keywords/immunology |
| keywords[0].score | 0.6992197036743164 |
| keywords[0].display_name | Immunology |
| keywords[1].id | https://openalex.org/keywords/influenza-vaccine |
| keywords[1].score | 0.6737121939659119 |
| keywords[1].display_name | Influenza vaccine |
| keywords[2].id | https://openalex.org/keywords/immune-system |
| keywords[2].score | 0.6265803575515747 |
| keywords[2].display_name | Immune system |
| keywords[3].id | https://openalex.org/keywords/medicine |
| keywords[3].score | 0.6228050589561462 |
| keywords[3].display_name | Medicine |
| keywords[4].id | https://openalex.org/keywords/virology |
| keywords[4].score | 0.57911217212677 |
| keywords[4].display_name | Virology |
| keywords[5].id | https://openalex.org/keywords/human-immunodeficiency-virus |
| keywords[5].score | 0.4857078492641449 |
| keywords[5].display_name | Human immunodeficiency virus (HIV) |
| keywords[6].id | https://openalex.org/keywords/intramuscular-injection |
| keywords[6].score | 0.4568432569503784 |
| keywords[6].display_name | Intramuscular injection |
| keywords[7].id | https://openalex.org/keywords/hiv-vaccine |
| keywords[7].score | 0.42378777265548706 |
| keywords[7].display_name | HIV vaccine |
| keywords[8].id | https://openalex.org/keywords/aids-vaccines |
| keywords[8].score | 0.4170820415019989 |
| keywords[8].display_name | AIDS Vaccines |
| keywords[9].id | https://openalex.org/keywords/vaccination |
| keywords[9].score | 0.297446608543396 |
| keywords[9].display_name | Vaccination |
| keywords[10].id | https://openalex.org/keywords/vaccine-trial |
| keywords[10].score | 0.16149449348449707 |
| keywords[10].display_name | Vaccine trial |
| keywords[11].id | https://openalex.org/keywords/internal-medicine |
| keywords[11].score | 0.08173355460166931 |
| keywords[11].display_name | Internal medicine |
| language | en |
| locations[0].id | doi:10.1093/infdis/jiz205 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S54542293 |
| locations[0].source.issn | 0022-1899, 1537-6613 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0022-1899 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | The Journal of Infectious Diseases |
| locations[0].source.host_organization | https://openalex.org/P4310311648 |
| locations[0].source.host_organization_name | Oxford University Press |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310311648 |
| locations[0].license | |
| locations[0].pdf_url | https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | The Journal of Infectious Diseases |
| locations[0].landing_page_url | https://doi.org/10.1093/infdis/jiz205 |
| locations[1].id | pmid:31045222 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | The Journal of infectious diseases |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/31045222 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11298778 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | J Infect Dis |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11298778 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5023150446 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-4960-2101 |
| authorships[0].author.display_name | Samuel Amoah |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[0].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I1325736334 |
| authorships[0].affiliations[1].raw_affiliation_string | Battelle Memorial Institute, Atlanta, Georgia |
| authorships[0].institutions[0].id | https://openalex.org/I1325736334 |
| authorships[0].institutions[0].ror | https://ror.org/01h5tnr73 |
| authorships[0].institutions[0].type | nonprofit |
| authorships[0].institutions[0].lineage | https://openalex.org/I1325736334 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Battelle |
| authorships[0].institutions[1].id | https://openalex.org/I19085752 |
| authorships[0].institutions[1].ror | https://ror.org/05je2tx78 |
| authorships[0].institutions[1].type | facility |
| authorships[0].institutions[1].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Samuel Amoah |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Battelle Memorial Institute, Atlanta, Georgia, Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[1].author.id | https://openalex.org/A5021713133 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Margarita Mishina |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[1].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I1325736334 |
| authorships[1].affiliations[1].raw_affiliation_string | Battelle Memorial Institute, Atlanta, Georgia |
| authorships[1].institutions[0].id | https://openalex.org/I1325736334 |
| authorships[1].institutions[0].ror | https://ror.org/01h5tnr73 |
| authorships[1].institutions[0].type | nonprofit |
| authorships[1].institutions[0].lineage | https://openalex.org/I1325736334 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Battelle |
| authorships[1].institutions[1].id | https://openalex.org/I19085752 |
| authorships[1].institutions[1].ror | https://ror.org/05je2tx78 |
| authorships[1].institutions[1].type | facility |
| authorships[1].institutions[1].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Margarita Mishina |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Battelle Memorial Institute, Atlanta, Georgia, Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[2].author.id | https://openalex.org/A5070508934 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-4593-0247 |
| authorships[2].author.display_name | Prabda Praphasiri |
| authorships[2].affiliations[0].raw_affiliation_string | Influenza Program, Bangkok, Thailand |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Prabda Praphasiri |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Influenza Program, Bangkok, Thailand |
| authorships[3].author.id | https://openalex.org/A5015591780 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-5794-9685 |
| authorships[3].author.display_name | Weiping Cao |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[3].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[3].institutions[0].id | https://openalex.org/I19085752 |
| authorships[3].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[3].institutions[0].type | facility |
| authorships[3].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Weiping Cao |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[4].author.id | https://openalex.org/A5012887239 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-6786-3482 |
| authorships[4].author.display_name | Jin Hyang Kim |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[4].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[4].institutions[0].id | https://openalex.org/I19085752 |
| authorships[4].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[4].institutions[0].type | facility |
| authorships[4].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Jin Hyang Kim |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[5].author.id | https://openalex.org/A5070296603 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Justine S. Liepkalns |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[5].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[5].institutions[0].id | https://openalex.org/I19085752 |
| authorships[5].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[5].institutions[0].type | facility |
| authorships[5].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Justine S Liepkalns |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[6].author.id | https://openalex.org/A5108410712 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Zhu Guo |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[6].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[6].institutions[0].id | https://openalex.org/I19085752 |
| authorships[6].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[6].institutions[0].type | facility |
| authorships[6].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Zhu Guo |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[7].author.id | https://openalex.org/A5034817308 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | P.J. Carney |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[7].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[7].institutions[0].id | https://openalex.org/I19085752 |
| authorships[7].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[7].institutions[0].type | facility |
| authorships[7].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Paul J Carney |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[8].author.id | https://openalex.org/A5103776786 |
| authorships[8].author.orcid | |
| authorships[8].author.display_name | Jessie Chang |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[8].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[8].institutions[0].id | https://openalex.org/I19085752 |
| authorships[8].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[8].institutions[0].type | facility |
| authorships[8].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Jessie C Chang |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[9].author.id | https://openalex.org/A5102976597 |
| authorships[9].author.orcid | https://orcid.org/0000-0001-6116-0997 |
| authorships[9].author.display_name | Stefan Fernandez |
| authorships[9].countries | TH |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I4210112607 |
| authorships[9].affiliations[0].raw_affiliation_string | Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand |
| authorships[9].institutions[0].id | https://openalex.org/I4210112607 |
| authorships[9].institutions[0].ror | https://ror.org/023swxh49 |
| authorships[9].institutions[0].type | nonprofit |
| authorships[9].institutions[0].lineage | https://openalex.org/I2801080794, https://openalex.org/I4210112607, https://openalex.org/I4387156032 |
| authorships[9].institutions[0].country_code | TH |
| authorships[9].institutions[0].display_name | Armed Forces Research Institute of Medical Science |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Stefan Fernandez |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand |
| authorships[10].author.id | https://openalex.org/A5049013080 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-9345-6669 |
| authorships[10].author.display_name | Shikha Garg |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[10].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[10].institutions[0].id | https://openalex.org/I19085752 |
| authorships[10].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[10].institutions[0].type | facility |
| authorships[10].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Shikha Garg |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[11].author.id | https://openalex.org/A5003814092 |
| authorships[11].author.orcid | |
| authorships[11].author.display_name | Lauren Beacham |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I1325736334 |
| authorships[11].affiliations[0].raw_affiliation_string | Battelle Memorial Institute, Atlanta, Georgia |
| authorships[11].affiliations[1].institution_ids | https://openalex.org/I19085752 |
| authorships[11].affiliations[1].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[11].institutions[0].id | https://openalex.org/I1325736334 |
| authorships[11].institutions[0].ror | https://ror.org/01h5tnr73 |
| authorships[11].institutions[0].type | nonprofit |
| authorships[11].institutions[0].lineage | https://openalex.org/I1325736334 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | Battelle |
| authorships[11].institutions[1].id | https://openalex.org/I19085752 |
| authorships[11].institutions[1].ror | https://ror.org/05je2tx78 |
| authorships[11].institutions[1].type | facility |
| authorships[11].institutions[1].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[11].institutions[1].country_code | US |
| authorships[11].institutions[1].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Lauren Beacham |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Battelle Memorial Institute, Atlanta, Georgia, Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[12].author.id | https://openalex.org/A5041860760 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-3874-0886 |
| authorships[12].author.display_name | Timothy H. Holtz |
| authorships[12].countries | TH, US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I1315836254 |
| authorships[12].affiliations[0].raw_affiliation_string | HIV/STD Research Program, Thailand Ministry of Public Health–CDC Collaboration, Nonthaburi, Bangkok, Thailand |
| authorships[12].affiliations[1].institution_ids | https://openalex.org/I1289490764, https://openalex.org/I4210113904 |
| authorships[12].affiliations[1].raw_affiliation_string | Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia |
| authorships[12].institutions[0].id | https://openalex.org/I1315836254 |
| authorships[12].institutions[0].ror | https://ror.org/03rn0z073 |
| authorships[12].institutions[0].type | government |
| authorships[12].institutions[0].lineage | https://openalex.org/I1315836254 |
| authorships[12].institutions[0].country_code | TH |
| authorships[12].institutions[0].display_name | Ministry of Public Health |
| authorships[12].institutions[1].id | https://openalex.org/I1289490764 |
| authorships[12].institutions[1].ror | https://ror.org/042twtr12 |
| authorships[12].institutions[1].type | government |
| authorships[12].institutions[1].lineage | https://openalex.org/I1289490764, https://openalex.org/I1299022934 |
| authorships[12].institutions[1].country_code | US |
| authorships[12].institutions[1].display_name | Centers for Disease Control and Prevention |
| authorships[12].institutions[2].id | https://openalex.org/I4210113904 |
| authorships[12].institutions[2].ror | https://ror.org/01wjn2x92 |
| authorships[12].institutions[2].type | facility |
| authorships[12].institutions[2].lineage | https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I4210109567, https://openalex.org/I4210113904 |
| authorships[12].institutions[2].country_code | US |
| authorships[12].institutions[2].display_name | National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Timothy H Holtz |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, HIV/STD Research Program, Thailand Ministry of Public Health–CDC Collaboration, Nonthaburi, Bangkok, Thailand |
| authorships[13].author.id | https://openalex.org/A5087093717 |
| authorships[13].author.orcid | https://orcid.org/0000-0003-3481-3889 |
| authorships[13].author.display_name | Marcel E. Curlin |
| authorships[13].countries | TH |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I4210112607 |
| authorships[13].affiliations[0].raw_affiliation_string | Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand |
| authorships[13].institutions[0].id | https://openalex.org/I4210112607 |
| authorships[13].institutions[0].ror | https://ror.org/023swxh49 |
| authorships[13].institutions[0].type | nonprofit |
| authorships[13].institutions[0].lineage | https://openalex.org/I2801080794, https://openalex.org/I4210112607, https://openalex.org/I4387156032 |
| authorships[13].institutions[0].country_code | TH |
| authorships[13].institutions[0].display_name | Armed Forces Research Institute of Medical Science |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Marcel E Curlin |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand |
| authorships[14].author.id | https://openalex.org/A5011899904 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-6609-376X |
| authorships[14].author.display_name | Fatimah S. Dawood |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[14].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[14].institutions[0].id | https://openalex.org/I19085752 |
| authorships[14].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[14].institutions[0].type | facility |
| authorships[14].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Fatimah Dawood |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[15].author.id | https://openalex.org/A5028415744 |
| authorships[15].author.orcid | https://orcid.org/0000-0002-8983-1913 |
| authorships[15].author.display_name | Sonja J. Olsen |
| authorships[15].countries | US |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[15].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[15].institutions[0].id | https://openalex.org/I19085752 |
| authorships[15].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[15].institutions[0].type | facility |
| authorships[15].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[15].institutions[0].country_code | US |
| authorships[15].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Sonja J Olsen |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[16].author.id | https://openalex.org/A5066705529 |
| authorships[16].author.orcid | https://orcid.org/0000-0001-6217-9665 |
| authorships[16].author.display_name | Shivaprakash Gangappa |
| authorships[16].countries | US |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[16].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[16].institutions[0].id | https://openalex.org/I19085752 |
| authorships[16].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[16].institutions[0].type | facility |
| authorships[16].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[16].institutions[0].country_code | US |
| authorships[16].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Shivaprakash Gangappa |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[17].author.id | https://openalex.org/A5015505628 |
| authorships[17].author.orcid | https://orcid.org/0000-0003-2352-3886 |
| authorships[17].author.display_name | James Stevens |
| authorships[17].countries | US |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[17].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[17].institutions[0].id | https://openalex.org/I19085752 |
| authorships[17].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[17].institutions[0].type | facility |
| authorships[17].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[17].institutions[0].country_code | US |
| authorships[17].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | James Stevens |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[18].author.id | https://openalex.org/A5010891569 |
| authorships[18].author.orcid | https://orcid.org/0000-0002-4715-5793 |
| authorships[18].author.display_name | Suryaprakash Sambhara |
| authorships[18].countries | US |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I19085752 |
| authorships[18].affiliations[0].raw_affiliation_string | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| authorships[18].institutions[0].id | https://openalex.org/I19085752 |
| authorships[18].institutions[0].ror | https://ror.org/05je2tx78 |
| authorships[18].institutions[0].type | facility |
| authorships[18].institutions[0].lineage | https://openalex.org/I1289490764, https://openalex.org/I1289490764, https://openalex.org/I1299022934, https://openalex.org/I1299022934, https://openalex.org/I19085752, https://openalex.org/I4210109567 |
| authorships[18].institutions[0].country_code | US |
| authorships[18].institutions[0].display_name | National Center for Immunization and Respiratory Diseases |
| authorships[18].author_position | last |
| authorships[18].raw_author_name | Suryaprakash Sambhara |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, Georgia |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdf |
| open_access.oa_status | bronze |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Standard-Dose Intradermal Influenza Vaccine Elicits Cellular Immune Responses Similar to Those of Intramuscular Vaccine in Men With and Those Without HIV Infection |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10167 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2713 |
| primary_topic.subfield.display_name | Epidemiology |
| primary_topic.display_name | Influenza Virus Research Studies |
| related_works | https://openalex.org/W1970192083, https://openalex.org/W2312275443, https://openalex.org/W2050317773, https://openalex.org/W3036790611, https://openalex.org/W2000886957, https://openalex.org/W4231888112, https://openalex.org/W4292218470, https://openalex.org/W2069046591, https://openalex.org/W4387043892, https://openalex.org/W2403958423 |
| cited_by_count | 7 |
| counts_by_year[0].year | 2024 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2023 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2022 |
| counts_by_year[2].cited_by_count | 2 |
| counts_by_year[3].year | 2021 |
| counts_by_year[3].cited_by_count | 1 |
| counts_by_year[4].year | 2020 |
| counts_by_year[4].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1093/infdis/jiz205 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S54542293 |
| best_oa_location.source.issn | 0022-1899, 1537-6613 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0022-1899 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | The Journal of Infectious Diseases |
| best_oa_location.source.host_organization | https://openalex.org/P4310311648 |
| best_oa_location.source.host_organization_name | Oxford University Press |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310311648 |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | The Journal of Infectious Diseases |
| best_oa_location.landing_page_url | https://doi.org/10.1093/infdis/jiz205 |
| primary_location.id | doi:10.1093/infdis/jiz205 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S54542293 |
| primary_location.source.issn | 0022-1899, 1537-6613 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0022-1899 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | The Journal of Infectious Diseases |
| primary_location.source.host_organization | https://openalex.org/P4310311648 |
| primary_location.source.host_organization_name | Oxford University Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310311648 |
| primary_location.license | |
| primary_location.pdf_url | https://academic.oup.com/jid/article-pdf/220/5/743/29021468/jiz205.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | The Journal of Infectious Diseases |
| primary_location.landing_page_url | https://doi.org/10.1093/infdis/jiz205 |
| publication_date | 2019-04-24 |
| publication_year | 2019 |
| referenced_works | https://openalex.org/W2775569101, https://openalex.org/W1978959016, https://openalex.org/W2024600835, https://openalex.org/W2024410915, https://openalex.org/W2291521219, https://openalex.org/W2013703920, https://openalex.org/W2102768133, https://openalex.org/W2034719295, https://openalex.org/W1990267419, https://openalex.org/W2226174505, https://openalex.org/W1977402511, https://openalex.org/W2095867033, https://openalex.org/W2167360046, https://openalex.org/W2148140586, https://openalex.org/W1965031244, https://openalex.org/W2026391844, https://openalex.org/W2172074761, https://openalex.org/W2157034871, https://openalex.org/W6676402146, https://openalex.org/W1990429464, https://openalex.org/W2405542601, https://openalex.org/W1965145857, https://openalex.org/W2093138102, https://openalex.org/W2076787697, https://openalex.org/W2036182565, https://openalex.org/W2144597286, https://openalex.org/W1976629220, https://openalex.org/W2089532164, https://openalex.org/W2107587363 |
| referenced_works_count | 29 |
| abstract_inverted_index.A | 87 |
| abstract_inverted_index.B | 118 |
| abstract_inverted_index.G | 90 |
| abstract_inverted_index.a | 9, 20, 26, 42, 106, 137, 148, 213 |
| abstract_inverted_index.28 | 123 |
| abstract_inverted_index.79 | 70, 74 |
| abstract_inverted_index.at | 8, 169 |
| abstract_inverted_index.be | 225 |
| abstract_inverted_index.by | 133 |
| abstract_inverted_index.in | 34, 36, 39, 69, 102, 128, 192, 209 |
| abstract_inverted_index.no | 180 |
| abstract_inverted_index.of | 12, 45, 80, 110, 115, 141, 152, 157, 177, 217 |
| abstract_inverted_index.on | 121, 182 |
| abstract_inverted_index.or | 93, 164, 189, 194 |
| abstract_inverted_index.to | 204, 224, 227 |
| abstract_inverted_index.we | 16 |
| abstract_inverted_index.IgG | 116 |
| abstract_inverted_index.The | 78, 113, 155, 175 |
| abstract_inverted_index.and | 55, 60, 73, 88, 144, 200 |
| abstract_inverted_index.are | 7 |
| abstract_inverted_index.day | 122 |
| abstract_inverted_index.did | 82, 159 |
| abstract_inverted_index.had | 179 |
| abstract_inverted_index.men | 72 |
| abstract_inverted_index.not | 32, 83, 160 |
| abstract_inverted_index.the | 85, 103, 129, 134, 145, 162, 198 |
| abstract_inverted_index.CD4+ | 107, 138, 149, 163, 214 |
| abstract_inverted_index.CD8+ | 165 |
| abstract_inverted_index.With | 197 |
| abstract_inverted_index.does | 31 |
| abstract_inverted_index.have | 17 |
| abstract_inverted_index.men. | 76 |
| abstract_inverted_index.need | 223 |
| abstract_inverted_index.risk | 11 |
| abstract_inverted_index.that | 19 |
| abstract_inverted_index.this | 40, 229 |
| abstract_inverted_index.were | 67, 99, 126 |
| abstract_inverted_index.with | 105, 136, 147, 212 |
| abstract_inverted_index.(IgG) | 91 |
| abstract_inverted_index.2–, | 57 |
| abstract_inverted_index.Human | 2 |
| abstract_inverted_index.after | 124, 172 |
| abstract_inverted_index.being | 207 |
| abstract_inverted_index.cells | 119 |
| abstract_inverted_index.count | 109, 140, 151, 216 |
| abstract_inverted_index.group | 104, 135, 146 |
| abstract_inverted_index.route | 79, 156, 176 |
| abstract_inverted_index.shown | 18 |
| abstract_inverted_index.these | 98 |
| abstract_inverted_index.times | 171 |
| abstract_inverted_index.tumor | 61 |
| abstract_inverted_index.virus | 4 |
| abstract_inverted_index.B-cell | 95, 190 |
| abstract_inverted_index.T-cell | 65, 108, 139, 150, 166, 187, 215 |
| abstract_inverted_index.affect | 84, 161 |
| abstract_inverted_index.effect | 181 |
| abstract_inverted_index.factor | 63 |
| abstract_inverted_index.group, | 131 |
| abstract_inverted_index.higher | 10 |
| abstract_inverted_index.immune | 47, 202 |
| abstract_inverted_index.memory | 94, 117 |
| abstract_inverted_index.result | 33 |
| abstract_inverted_index.severe | 13 |
| abstract_inverted_index.titers | 38 |
| abstract_inverted_index.trials | 232 |
| abstract_inverted_index.versus | 25 |
| abstract_inverted_index.γ–, | 59 |
| abstract_inverted_index.≥200 | 142 |
| abstract_inverted_index.<200 | 111, 153, 218 |
| abstract_inverted_index.B-cell, | 54 |
| abstract_inverted_index.Methods | 51 |
| abstract_inverted_index.Results | 77 |
| abstract_inverted_index.highest | 127 |
| abstract_inverted_index.passive | 220 |
| abstract_inverted_index.persons | 6 |
| abstract_inverted_index.protect | 228 |
| abstract_inverted_index.remains | 49 |
| abstract_inverted_index.vaccine | 24, 30 |
| abstract_inverted_index.various | 170 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Although | 15 |
| abstract_inverted_index.Clinical | 231 |
| abstract_inverted_index.although | 97 |
| abstract_inverted_index.antibody | 183, 185 |
| abstract_inverted_index.assessed | 68 |
| abstract_inverted_index.avidity, | 186 |
| abstract_inverted_index.cellular | 201 |
| abstract_inverted_index.explored | 226 |
| abstract_inverted_index.followed | 132 |
| abstract_inverted_index.impaired | 101, 208 |
| abstract_inverted_index.lacking. | 50 |
| abstract_inverted_index.measured | 120, 168 |
| abstract_inverted_index.necrosis | 62 |
| abstract_inverted_index.severely | 100 |
| abstract_inverted_index.cells/μL | 143 |
| abstract_inverted_index.influenza | 23, 29, 205 |
| abstract_inverted_index.response, | 96 |
| abstract_inverted_index.responses | 48, 66, 167, 191, 203 |
| abstract_inverted_index.subjects. | 196 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.cells/μL, | 219 |
| abstract_inverted_index.cells/μL. | 112, 154 |
| abstract_inverted_index.influenza. | 14 |
| abstract_inverted_index.interferon | 58 |
| abstract_inverted_index.responses, | 184, 188 |
| abstract_inverted_index.strategies | 222 |
| abstract_inverted_index.Conclusions | 174 |
| abstract_inverted_index.differences | 35 |
| abstract_inverted_index.examination | 44 |
| abstract_inverted_index.frequencies | 114 |
| abstract_inverted_index.individuals | 211 |
| abstract_inverted_index.interleukin | 56 |
| abstract_inverted_index.intradermal | 22 |
| abstract_inverted_index.plasmablast | 92 |
| abstract_inverted_index.population, | 41 |
| abstract_inverted_index.population. | 230 |
| abstract_inverted_index.serological | 199 |
| abstract_inverted_index.vaccination | 81, 125, 158, 178, 206 |
| abstract_inverted_index.HIV-infected | 71, 193, 210 |
| abstract_inverted_index.NCT01538940. | 234 |
| abstract_inverted_index.Serological, | 52 |
| abstract_inverted_index.immunization | 221 |
| abstract_inverted_index.registration | 233 |
| abstract_inverted_index.vaccination. | 173 |
| abstract_inverted_index.cell-mediated | 46 |
| abstract_inverted_index.comprehensive | 43 |
| abstract_inverted_index.intramuscular | 28 |
| abstract_inverted_index.standard-dose | 21, 27 |
| abstract_inverted_index.HIV-uninfected | 75, 130, 195 |
| abstract_inverted_index.immunoglobulin | 86, 89 |
| abstract_inverted_index.α–secreting | 64 |
| abstract_inverted_index.(HIV)–infected | 5 |
| abstract_inverted_index.antigen-specific | 53 |
| abstract_inverted_index.immunodeficiency | 3 |
| abstract_inverted_index.hemagglutination-inhibition | 37 |
| cited_by_percentile_year.max | 96 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 19 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8399999737739563 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.69956912 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |