arXiv (Cornell University)
Substituting Gadolinium in Brain MRI Using DeepContrast
January 2020 • Haoran Sun, Xueqing Liu, Xinyang Feng, Chen Liu, Nanyan Zhu, Sabrina Gjerswold-Selleck, Hongjian Wei, Pavan S. Upadhyayula, Angeliki Mela, Cheng‐Chia…
Cerebral blood volume (CBV) is a hemodynamic correlate of oxygen metabolism and reflects brain activity and function. High-resolution CBV maps can be generated using the steady-state gadolinium-enhanced MRI technique. Such a technique requires an intravenous injection of exogenous gadolinium based contrast agent (GBCA) and recent studies suggest that the GBCA can accumulate in the brain after frequent use. We hypothesize that endogenous sources of contrast might exist within the most conventional and commonly acqu…