Supplemental Tables from CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies Article Swipe

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Marina Bacac , Sara Colombetti , Sylvia Herter , Johannes Sam , Mario Perro , Stanford Chen , Roberta Bianchi , Marine Richard , Anne Schoenle , Valeria Nicolini , Sarah Diggelmann , Florian Limani , Ramona Schlenker , Tamara Hüsser , W. Richter , Katharine Bray‐French , Heather Hinton , Anna Maria Giusti , Anne Freimoser–Grundschober , Laurent Larivière , Christiane Neumann , Christian Klein , Pablo Umaña ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1158/1078-0432.22470708

Supplemental Table 1. Overview of CD20-targeting T-cell bispecific molecules evaluated in the current study. Supplemental Table 2. Tumor cell lines and EC50 values of tumor cell lysis. Supplemental Table 3. Assessment of the activity in ex vivo primary tumor samples derived from aggressive lymphoma and leukemia patients. Supplemental Table 4. Absolute values of cytokines measured by multiplex analysis of blood samples reported as heatmap in Figure 3e, 4b, 5d, and 6b. Supplemental Table 5. Average score of perivascular CD3 positive T-cells in the lung (assessed by blinded pathologist analysis) referring to T-cell staining of lungs from tumor-bearing, HSC NSG mice 7 days after the first treatment and 24 h after the second treatment (treatment groups are indicated on Figure 6D panels).

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CD20 Medicine CD3 Lymphoma Internal medicine Ex vivo Leukemia Oncology Cancer research Immunology In vivo Biology Antigen CD8 Biotechnology

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/1078-0432.22470708
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Title: Supplemental Tables from CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

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Authors: Marina Bacac, Sara Colombetti, Sylvia Herter, Johannes Sam, Mario Perro, Stanford Chen, Roberta Bianchi, Marine Richard, Anne Schoenle, Valeria Nicolini, Sarah Diggelmann, Florian Limani, Ramona Schlenker, Tamara Hüsser, W. Richter, Katharine Bray‐French, Heather Hinton, Anna Maria Giusti, Anne Freimoser–Grundschober, Laurent Larivière, Christiane Neumann, Christian Klein, Pablo Umaña

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Concepts: CD20, Medicine, CD3, Lymphoma, Internal medicine, Ex vivo, Leukemia, Oncology, Cancer research, Immunology, In vivo, Biology, Antigen, CD8, Biotechnology

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abstract_inverted_index.pathologist	87
abstract_inverted_index.Supplemental	14, 27, 47, 71
abstract_inverted_index.perivascular	77
abstract_inverted_index.CD20-targeting	5
abstract_inverted_index.tumor-bearing,	96
abstract_inverted_index.panels).</p>	120
abstract_inverted_index.<p>Supplemental	0
cited_by_percentile_year
countries_distinct_count	0
institutions_distinct_count	23
sustainable_development_goals[0].id	https://metadata.un.org/sdg/3
sustainable_development_goals[0].score	0.4699999988079071
sustainable_development_goals[0].display_name	Good health and well-being
citation_normalized_percentile.value	0.19937347
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False