Supplementary Data from IL6/STAT3 Signaling Orchestrates Premetastatic Niche Formation and Immunosuppressive Traits in Lung Article Swipe
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· 2023
· Open Access
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· DOI: https://doi.org/10.1158/0008-5472.22424955.v1
· OA: W4361256578
<p>Supplementary Fig. S1-S6, supplementary methods, supplementary table S1-S2. Supplementary Table S1. Primers used in the study; Supplementary Table S2. Antibodies information for flow cytometry analysis; Figure S1. IL6/ Gp130 pathway is involved in maintenance of stemness and in suppression of host immunity for lung metastasis; Figure S2. IL6 signaling is essential for lung metastasis in Gprc5a-ko mice lung tissues; Figure S3. IL6 signaling is essential for Lewis lung carcinoma cells in lung metastasis in Gprc5a-ko mice lung tissues; Figure S4. IL-6 signaling mediates the inhibition on innate immunity in Gprc5a-ko mouse lungs; Figure S5. IL-6 signaling orchestrates the inhibition on innate and adaptive immunity in Gprc5a-ko mouse lungs; Figure S6. Proposed model of IL-6/STAT3 signaling in lung metastasis</p>
