Supplementary Data S1 from SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance Article Swipe

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Kristen Jensen-Pergakes , John Tatlock , Karen A. Maegley , Indrawan McAlpine , Michele McTigue , Tao Xie , Christopher P. Dillon , Yuli Wang , Shinji Yamazaki , Noah Spiegel , Manli Shi , Amy Nemeth , Natalie Miller , Eleanore Hendrickson , Hieu Lam , John Sherrill , Chi‐Yeh Chung , Elizabeth A. McMillan , Shannon Karlicek Bryant , Prakash B. Palde , John Braganza , Alexei Brooun , Ya‐Li Deng , Vesta Goshtasbi , Susan E. Kephart , Robert A. Kumpf , Wei Liu , Ryan L. Patman , Eugene Rui , Stephanie Scales , Michelle Tran‐Dubé , Fen Wang , Martin Wythes , Thomas A. Paul ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1158/1535-7163.22522843.v1

Whole exome sequencing results from PRMT5 inhibitor resistant cells

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RNA splicing Pharmacology Drug Liability Drug resistance Medicine Business Biology Genetics Accounting Gene RNA

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/1535-7163.22522843.v1
OA Status: gold
Related Works: 10
OpenAlex ID: https://openalex.org/W4362624736

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DOI: https://doi.org/10.1158/1535-7163.22522843.v1

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Title: Supplementary Data S1 from SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

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Language: en

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Publication year: 2023

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Publication date: 2023-04-03

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Authors: Kristen Jensen-Pergakes, John Tatlock, Karen A. Maegley, Indrawan McAlpine, Michele McTigue, Tao Xie, Christopher P. Dillon, Yuli Wang, Shinji Yamazaki, Noah Spiegel, Manli Shi, Amy Nemeth, Natalie Miller, Eleanore Hendrickson, Hieu Lam, John Sherrill, Chi‐Yeh Chung, Elizabeth A. McMillan, Shannon Karlicek Bryant, Prakash B. Palde, John Braganza, Alexei Brooun, Ya‐Li Deng, Vesta Goshtasbi, Susan E. Kephart, Robert A. Kumpf, Wei Liu, Ryan L. Patman, Eugene Rui, Stephanie Scales, Michelle Tran‐Dubé, Fen Wang, Martin Wythes, Thomas A. Paul

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Landing page: https://doi.org/10.1158/1535-7163.22522843.v1

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Concepts: RNA splicing, Pharmacology, Drug, Liability, Drug resistance, Medicine, Business, Biology, Genetics, Accounting, Gene, RNA

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