Supplementary Fig.S9 from Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers Article Swipe

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Wei Zhou , Peng Fang , Dongan Yu , Hongyuan Ren , Meng You , Long Yin , Fei Mei , Huikai Zhu , Zhenzhen Wang , Hui Xu , Yuxia Cao , Xiaowei Sun , Xiaohong Xu , Jianjun Bi , Wang Jin , Lanping Ma , Xin Wang , Lin Chen , Yong-liang Zhang , Xiaowei Cen , Xi Zhu , Li-guang Lou , Datao Liu , Xiaoding Tan , Jinliang Yang , Tao Meng , Jingkang Shen ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1158/1535-7163.30733750

Affinity of 9MW2821 and enfortumab vedotin (EV) to recombinant human Fcγ and FcRn receptors based on surface plasmon resonance measurements.

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Conjugate Medicine Pharmacology Recombinant DNA Surface plasmon resonance Cancer Cancer research Dosing Antibody-drug conjugate Internal medicine Receptor Pharmacokinetics Oncology Drug Clinical trial

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Landing Page: https://doi.org/10.1158/1535-7163.30733750
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Title: Supplementary Fig.S9 from Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers

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Publication year: 2025

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Publication date: 2025-11-27

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Authors: Wei Zhou, Peng Fang, Dongan Yu, Hongyuan Ren, Meng You, Long Yin, Fei Mei, Huikai Zhu, Zhenzhen Wang, Hui Xu, Yuxia Cao, Xiaowei Sun, Xiaohong Xu, Jianjun Bi, Wang Jin, Lanping Ma, Xin Wang, Lin Chen, Yong-liang Zhang, Xiaowei Cen, Xi Zhu, Li-guang Lou, Datao Liu, Xiaoding Tan, Jinliang Yang, Tao Meng, Jingkang Shen

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Landing page: https://doi.org/10.1158/1535-7163.30733750

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Concepts: Conjugate, Medicine, Pharmacology, Recombinant DNA, Surface plasmon resonance, Cancer, Cancer research, Dosing, Antibody-drug conjugate, Internal medicine, Receptor, Pharmacokinetics, Oncology, Drug, Clinical trial

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