Supplementary figure 2 from Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody–Drug Conjugates Article Swipe

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Saskia Schmitt , Paul Machui , Isabelle Mai , Sarah Herterich , Swetlana Wunder , Philipp Cyprys , Marcus Gerlach , Philipp Ochtrop , Christian P. R. Hackenberger , Dominik Schumacher , Jonas Helma , Annette M. Vogl , Marc‐André Kasper ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1158/1535-7163.25124869.v1

Analytical SEC chromatograms of trastuzumab-LP3 DAR8, trastuzumab-LP5 DAR8 and Enhertu at day 0 and after storage for four weeks at 4°C and 37°C in the dark.

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Conjugate Drug Antibody-drug conjugate Pharmacology Antibody Combinatorial chemistry Chemistry Medicine Mathematics Immunology Monoclonal antibody Mathematical analysis

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/1535-7163.25124869.v1
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DOI: https://doi.org/10.1158/1535-7163.25124869.v1

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Title: Supplementary figure 2 from Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody–Drug Conjugates

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Language: en

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Publication year: 2024

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Authors: Saskia Schmitt, Paul Machui, Isabelle Mai, Sarah Herterich, Swetlana Wunder, Philipp Cyprys, Marcus Gerlach, Philipp Ochtrop, Christian P. R. Hackenberger, Dominik Schumacher, Jonas Helma, Annette M. Vogl, Marc‐André Kasper

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Concepts: Conjugate, Drug, Antibody-drug conjugate, Pharmacology, Antibody, Combinatorial chemistry, Chemistry, Medicine, Mathematics, Immunology, Monoclonal antibody, Mathematical analysis

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