Supplementary Figure 3 from Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination–Deficient Leukemia Cells Article Swipe

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Katherine Sullivan-Reed , Monika M. Toma , Małgorzata Drzewiecka , Margaret Nieborowska-Skorska , Reza Nejati , Adam Karami , Mariusz A. Wasik , Tomasz Śliwiński , Tomasz Skórski ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1158/1541-7786.24229698.v1

S3. Simultaneous inhibition of Polθ helicase and DNA polymerase activity exerted synergistic effect against RAD54-/- leukemia cells.

Related Topics

Dna Polymerase

Reverse Transcription Polymerase Chain Reaction

Concepts

Homologous recombination RAD52 DNA polymerase Polymerase Molecular biology Helicase Chemistry DNA Biology RAD51 Genetics Gene RNA

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/1541-7786.24229698.v1
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DOI: https://doi.org/10.1158/1541-7786.24229698.v1

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Title: Supplementary Figure 3 from Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination–Deficient Leukemia Cells

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Type: preprint

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Language: en

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Publication year: 2023

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Publication date: 2023-10-02

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Authors: Katherine Sullivan-Reed, Monika M. Toma, Małgorzata Drzewiecka, Margaret Nieborowska-Skorska, Reza Nejati, Adam Karami, Mariusz A. Wasik, Tomasz Śliwiński, Tomasz Skórski

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Landing page: https://doi.org/10.1158/1541-7786.24229698.v1

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Concepts: Homologous recombination, RAD52, DNA polymerase, Polymerase, Molecular biology, Helicase, Chemistry, DNA, Biology, RAD51, Genetics, Gene, RNA

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