Supplementary Figure 4 from Anti-HER2, High-DAR Antibody Fragment–Drug Conjugates with a Glucuronide-Based MMAE Linker–Payload Demonstrate Superior Efficacy over IgG-Based ADCs Article Swipe

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Ioanna Stamati , Gökhan Yahioglu , Soraya Diez-Posada , Anja Pomowski , Isabel Perez-Castro , A. Keith Stewart , Laura Bouché , Antony Constantinou , Benjamin J. Stenton , Savvas Saouros , Bryan Edwards , Sam Ness , Mahendra P. Deonarain ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1158/1535-7163.30029708

Supplementary Figure 4 showing biophysical data for the conjugation of a dummy payload to the TCT(H) scFv

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Linker Payload (computing) Conjugate Fragment (logic) Glucuronide Chemistry Antibody Drug Antibody-drug conjugate Computer science Medicine Combinatorial chemistry Pharmacology Computational biology Monoclonal antibody Algorithm Biochemistry Immunology Mathematics Biology Programming language Computer network Mathematical analysis Network packet Urine

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Type: article
Language: en
Landing Page: https://doi.org/10.1158/1535-7163.30029708
PDF: https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_4_from_Anti-HER2_High-DAR_Antibody_Fragment_Drug_Conjugates_with_a_Glucuronide-Based_MMAE_Linker_Payload_Demonstrate_Superior_Efficacy_over_IgG-Based_ADCs/30029708/1/files/57578024.pdf
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DOI: https://doi.org/10.1158/1535-7163.30029708

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Title: Supplementary Figure 4 from Anti-HER2, High-DAR Antibody Fragment–Drug Conjugates with a Glucuronide-Based MMAE Linker–Payload Demonstrate Superior Efficacy over IgG-Based ADCs

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Language: en

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Publication year: 2025

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Publication date: 2025-09-02

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Authors: Ioanna Stamati, Gökhan Yahioglu, Soraya Diez-Posada, Anja Pomowski, Isabel Perez-Castro, A. Keith Stewart, Laura Bouché, Antony Constantinou, Benjamin J. Stenton, Savvas Saouros, Bryan Edwards, Sam Ness, Mahendra P. Deonarain

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Landing page: https://doi.org/10.1158/1535-7163.30029708

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Concepts: Linker, Payload (computing), Conjugate, Fragment (logic), Glucuronide, Chemistry, Antibody, Drug, Antibody-drug conjugate, Computer science, Medicine, Combinatorial chemistry, Pharmacology, Computational biology, Monoclonal antibody, Algorithm, Biochemistry, Immunology, Mathematics, Biology, Programming language, Computer network, Mathematical analysis, Network packet, Urine

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countries_distinct_count	0
institutions_distinct_count	13
citation_normalized_percentile.value	0.50716623
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False