Supplementary Figure 6 from Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing Article Swipe

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Ellen Heitzer , Martina Auer , Christin Gasch , Martin Pichler , Peter Ulz , Eva Maria Hoffmann , Sigurd Lax , Julie Waldispuehl‐Geigl , Oliver Mauermann , Carolin Lackner , Gerald Höfler , Florian Eisner , Heinz Sill , Hellmut Samonigg , Klaus Pantel , Sabine Riethdorf , Thomas Bauernhofer , Jochen B. Geigl , Michael R. Speicher ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1158/0008-5472.22398303.v1

PDF file - 188K, Sequencing of UCR41 and flanking regions: UCR41 is a 217-bp-long ultra-conserved region depicted in dark green. The gray bar indicates the extremely conserved sequence. The region is flanked by two SNPs that are frequent in the European population (blue arrows). The black curve indicates the mutability, which is higher in non-conserved regions compared with conserved segments. The black bars illustrate the 5 overlapping amplicons used for amplification. Mutations identified in our samples are indicated with red arrows. The genomic coordinates refer to the hg18 assembly of the human genome. (The graph is reproduced with permission from De Grassi et al.)

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Biology

Conserved Sequence

Human Genome

Computational Biology

Evolutionary Biology

Dna

Polymerase Chain Reaction

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Amplicon Biology Genetics Genome Conserved sequence DNA sequencing Human genome Computational biology Evolutionary biology DNA Gene Base sequence Polymerase chain reaction

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/0008-5472.22398303.v1
PDF: https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_6_from_Complex_Tumor_Genomes_Inferred_from_Single_Circulating_Tumor_Cells_by_Array-CGH_and_Next-Generation_Sequencing/22398303/1/files/39844017.pdf
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DOI: https://doi.org/10.1158/0008-5472.22398303.v1

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Title: Supplementary Figure 6 from Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing

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Publication year: 2023

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Publication date: 2023-03-30

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Authors: Ellen Heitzer, Martina Auer, Christin Gasch, Martin Pichler, Peter Ulz, Eva Maria Hoffmann, Sigurd Lax, Julie Waldispuehl‐Geigl, Oliver Mauermann, Carolin Lackner, Gerald Höfler, Florian Eisner, Heinz Sill, Hellmut Samonigg, Klaus Pantel, Sabine Riethdorf, Thomas Bauernhofer, Jochen B. Geigl, Michael R. Speicher

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Landing page: https://doi.org/10.1158/0008-5472.22398303.v1

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Concepts: Amplicon, Biology, Genetics, Genome, Conserved sequence, DNA sequencing, Human genome, Computational biology, Evolutionary biology, DNA, Gene, Base sequence, Polymerase chain reaction

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institutions_distinct_count	19
citation_normalized_percentile.value	0.24528755
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False