-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax Article Swipe

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Antoine Pinton , Lucien Courtois , Charlotte Doublet , Aurélie Cabannes‐Hamy , Guillaume P. Andrieu , Charlotte Smith , Estelle Balducci , Agata Cieślak , Aurore Touzart , Mathieu Simonin , Véronique Lheritier , Françoise Huguet , Marie Balsat , Hervé Dombret , Philippe Rousselot , Salvatore Spicuglia , Elizabeth Macintyre , Nicolas Boissel , Vahid Asnafi ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1158/1078-0432.24947950.v1

Supplementary Figure 1 (A) Circos plot representing mutations co-occurrences in PHF6WT (left) and PHF6ALT T-ALL (right). (B) Variant allele frequencies (VAF) of mutations at diagnosis and relapse. Genes are ordered by decreasing VAF at diagnosis from left to right.

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Epigenetics

Biology

Gene Expression

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Promoter Epigenetics Genetics Allele Gene Psychology Biology Gene expression

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/1078-0432.24947950.v1
OA Status: gold
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Title: Supplementary Figure S1 from <i>PHF6</i>-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax

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Publication year: 2024

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Authors: Antoine Pinton, Lucien Courtois, Charlotte Doublet, Aurélie Cabannes‐Hamy, Guillaume P. Andrieu, Charlotte Smith, Estelle Balducci, Agata Cieślak, Aurore Touzart, Mathieu Simonin, Véronique Lheritier, Françoise Huguet, Marie Balsat, Hervé Dombret, Philippe Rousselot, Salvatore Spicuglia, Elizabeth Macintyre, Nicolas Boissel, Vahid Asnafi

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Landing page: https://doi.org/10.1158/1078-0432.24947950.v1

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Concepts: Promoter, Epigenetics, Genetics, Allele, Gene, Psychology, Biology, Gene expression

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