Supplementary Figure S2 from Efficacious Combination Drug Treatment for Colorectal Cancer That Overcomes Resistance to KRAS G12C Inhibitors Article Swipe

View

Hiroyuki Matsubara , Hiroyuki Miyoshi , Fumihiko Kakizaki , Tomonori Morimoto , Kenji Kawada , Takehito Yamamoto , Kazutaka Obama , Yoshiharu Sakai , Makoto Mark Taketo ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1158/1535-7163.30733948

Suppl. Fig. S2 with its legend on page 2

Related Topics

Adaptive Immune System

Pharmacology

Clinical Trial

Concepts

Medicine Colorectal cancer KRAS Drug Drug resistance Oncology Cancer research Cancer Internal medicine Drug treatment Cancer treatment Acquired resistance Pharmacology Clinical trial

Metadata

Type: article
Landing Page: https://doi.org/10.1158/1535-7163.30733948
OA Status: gold
OpenAlex ID: https://openalex.org/W7106787266

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W7106787266

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1158/1535-7163.30733948

Digital Object Identifier
Title: Supplementary Figure S2 from Efficacious Combination Drug Treatment for Colorectal Cancer That Overcomes Resistance to KRAS G12C Inhibitors

Work title
Type: article

OpenAlex work type
Publication year: 2025

Year of publication
Publication date: 2025-11-27

Full publication date if available
Authors: Hiroyuki Matsubara, Hiroyuki Miyoshi, Fumihiko Kakizaki, Tomonori Morimoto, Kenji Kawada, Takehito Yamamoto, Kazutaka Obama, Yoshiharu Sakai, Makoto Mark Taketo

List of authors in order
Landing page: https://doi.org/10.1158/1535-7163.30733948

Publisher landing page
Open access: Yes

Whether a free full text is available
OA status: gold

Open access status per OpenAlex
OA URL: https://doi.org/10.1158/1535-7163.30733948

Direct OA link when available
Concepts: Medicine, Colorectal cancer, KRAS, Drug, Drug resistance, Oncology, Cancer research, Cancer, Internal medicine, Drug treatment, Cancer treatment, Acquired resistance, Pharmacology, Clinical trial

Top concepts (fields/topics) attached by OpenAlex
Cited by: 0

Total citation count in OpenAlex

Full payload

id	https://openalex.org/W7106787266
doi	https://doi.org/10.1158/1535-7163.30733948
ids.doi	https://doi.org/10.1158/1535-7163.30733948
ids.openalex	https://openalex.org/W7106787266
fwci	0.0
type	article
title	Supplementary Figure S2 from Efficacious Combination Drug Treatment for Colorectal Cancer That Overcomes Resistance to KRAS G12C Inhibitors
biblio.issue
biblio.volume
biblio.last_page
biblio.first_page
is_xpac	False
apc_list
apc_paid
concepts[0].id	https://openalex.org/C71924100
concepts[0].level	0
concepts[0].score	0.8454325199127197
concepts[0].wikidata	https://www.wikidata.org/wiki/Q11190
concepts[0].display_name	Medicine
concepts[1].id	https://openalex.org/C526805850
concepts[1].level	3
concepts[1].score	0.6992115378379822
concepts[1].wikidata	https://www.wikidata.org/wiki/Q188874
concepts[1].display_name	Colorectal cancer
concepts[2].id	https://openalex.org/C2781187634
concepts[2].level	4
concepts[2].score	0.6779224872589111
concepts[2].wikidata	https://www.wikidata.org/wiki/Q20969980
concepts[2].display_name	KRAS
concepts[3].id	https://openalex.org/C2780035454
concepts[3].level	2
concepts[3].score	0.529918372631073
concepts[3].wikidata	https://www.wikidata.org/wiki/Q8386
concepts[3].display_name	Drug
concepts[4].id	https://openalex.org/C114851261
concepts[4].level	2
concepts[4].score	0.43231797218322754
concepts[4].wikidata	https://www.wikidata.org/wiki/Q12147416
concepts[4].display_name	Drug resistance
concepts[5].id	https://openalex.org/C143998085
concepts[5].level	1
concepts[5].score	0.3913666307926178
concepts[5].wikidata	https://www.wikidata.org/wiki/Q162555
concepts[5].display_name	Oncology
concepts[6].id	https://openalex.org/C502942594
concepts[6].level	1
concepts[6].score	0.37098464369773865
concepts[6].wikidata	https://www.wikidata.org/wiki/Q3421914
concepts[6].display_name	Cancer research
concepts[7].id	https://openalex.org/C121608353
concepts[7].level	2
concepts[7].score	0.33611756563186646
concepts[7].wikidata	https://www.wikidata.org/wiki/Q12078
concepts[7].display_name	Cancer
concepts[8].id	https://openalex.org/C126322002
concepts[8].level	1
concepts[8].score	0.32750383019447327
concepts[8].wikidata	https://www.wikidata.org/wiki/Q11180
concepts[8].display_name	Internal medicine
concepts[9].id	https://openalex.org/C2986900798
concepts[9].level	2
concepts[9].score	0.3161509335041046
concepts[9].wikidata	https://www.wikidata.org/wiki/Q5308926
concepts[9].display_name	Drug treatment
concepts[10].id	https://openalex.org/C3019816032
concepts[10].level	3
concepts[10].score	0.30272477865219116
concepts[10].wikidata	https://www.wikidata.org/wiki/Q2575340
concepts[10].display_name	Cancer treatment
concepts[11].id	https://openalex.org/C2994294914
concepts[11].level	3
concepts[11].score	0.29537680745124817
concepts[11].wikidata	https://www.wikidata.org/wiki/Q1645075
concepts[11].display_name	Acquired resistance
concepts[12].id	https://openalex.org/C98274493
concepts[12].level	1
concepts[12].score	0.2946704924106598
concepts[12].wikidata	https://www.wikidata.org/wiki/Q128406
concepts[12].display_name	Pharmacology
concepts[13].id	https://openalex.org/C535046627
concepts[13].level	2
concepts[13].score	0.2647415101528168
concepts[13].wikidata	https://www.wikidata.org/wiki/Q30612
concepts[13].display_name	Clinical trial
keywords[0].id	https://openalex.org/keywords/colorectal-cancer
keywords[0].score	0.6992115378379822
keywords[0].display_name	Colorectal cancer
keywords[1].id	https://openalex.org/keywords/kras
keywords[1].score	0.6779224872589111
keywords[1].display_name	KRAS
keywords[2].id	https://openalex.org/keywords/drug
keywords[2].score	0.529918372631073
keywords[2].display_name	Drug
keywords[3].id	https://openalex.org/keywords/drug-resistance
keywords[3].score	0.43231797218322754
keywords[3].display_name	Drug resistance
keywords[4].id	https://openalex.org/keywords/cancer
keywords[4].score	0.33611756563186646
keywords[4].display_name	Cancer
keywords[5].id	https://openalex.org/keywords/drug-treatment
keywords[5].score	0.3161509335041046
keywords[5].display_name	Drug treatment
language
locations[0].id	doi:10.1158/1535-7163.30733948
locations[0].is_oa	True
locations[0].source
locations[0].license	cc-by
locations[0].pdf_url
locations[0].version	acceptedVersion
locations[0].raw_type	posted-content
locations[0].license_id	https://openalex.org/licenses/cc-by
locations[0].is_accepted	True
locations[0].is_published	False
locations[0].raw_source_name
locations[0].landing_page_url	https://doi.org/10.1158/1535-7163.30733948
indexed_in	crossref
authorships[0].author.id	https://openalex.org/A2025697146
authorships[0].author.orcid	https://orcid.org/0000-0002-9279-5458
authorships[0].author.display_name	Hiroyuki Matsubara
authorships[0].author_position	first
authorships[0].raw_author_name	Hiroyuki Matsubara
authorships[0].is_corresponding	True
authorships[1].author.id	https://openalex.org/A2150578281
authorships[1].author.orcid	https://orcid.org/0000-0001-7400-0714
authorships[1].author.display_name	Hiroyuki Miyoshi
authorships[1].author_position	middle
authorships[1].raw_author_name	Hiroyuki Miyoshi
authorships[1].is_corresponding	False
authorships[2].author.id	https://openalex.org/A1978691034
authorships[2].author.orcid	https://orcid.org/0000-0003-2017-6700
authorships[2].author.display_name	Fumihiko Kakizaki
authorships[2].author_position	middle
authorships[2].raw_author_name	Fumihiko Kakizaki
authorships[2].is_corresponding	False
authorships[3].author.id	https://openalex.org/A2427074815
authorships[3].author.orcid	https://orcid.org/0000-0003-0535-0889
authorships[3].author.display_name	Tomonori Morimoto
authorships[3].author_position	middle
authorships[3].raw_author_name	Tomonori Morimoto
authorships[3].is_corresponding	False
authorships[4].author.id	https://openalex.org/A1938911419
authorships[4].author.orcid	https://orcid.org/0000-0003-4336-6937
authorships[4].author.display_name	Kenji Kawada
authorships[4].author_position	middle
authorships[4].raw_author_name	Kenji Kawada
authorships[4].is_corresponding	False
authorships[5].author.id	https://openalex.org/A2106142404
authorships[5].author.orcid	https://orcid.org/0000-0002-2236-7124
authorships[5].author.display_name	Takehito Yamamoto
authorships[5].author_position	middle
authorships[5].raw_author_name	Takehito Yamamoto
authorships[5].is_corresponding	False
authorships[6].author.id	https://openalex.org/A2058599804
authorships[6].author.orcid	https://orcid.org/0000-0003-2924-6701
authorships[6].author.display_name	Kazutaka Obama
authorships[6].author_position	middle
authorships[6].raw_author_name	Kazutaka Obama
authorships[6].is_corresponding	False
authorships[7].author.id	https://openalex.org/A2163678501
authorships[7].author.orcid	https://orcid.org/0000-0001-9864-4186
authorships[7].author.display_name	Yoshiharu Sakai
authorships[7].author_position	middle
authorships[7].raw_author_name	Yoshiharu Sakai
authorships[7].is_corresponding	False
authorships[8].author.id	https://openalex.org/A2250506730
authorships[8].author.orcid
authorships[8].author.display_name	Makoto Mark Taketo
authorships[8].author_position	last
authorships[8].raw_author_name	Makoto Mark Taketo
authorships[8].is_corresponding	False
has_content.pdf	False
has_content.grobid_xml	False
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://doi.org/10.1158/1535-7163.30733948
open_access.oa_status	gold
open_access.any_repository_has_fulltext	False
created_date	2025-11-28T00:00:00
display_name	Supplementary Figure S2 from Efficacious Combination Drug Treatment for Colorectal Cancer That Overcomes Resistance to KRAS G12C Inhibitors
has_fulltext	False
is_retracted	False
updated_date	2025-11-28T02:12:24.556248
primary_topic
cited_by_count	0
locations_count	1
best_oa_location.id	doi:10.1158/1535-7163.30733948
best_oa_location.is_oa	True
best_oa_location.source
best_oa_location.license	cc-by
best_oa_location.pdf_url
best_oa_location.version	acceptedVersion
best_oa_location.raw_type	posted-content
best_oa_location.license_id	https://openalex.org/licenses/cc-by
best_oa_location.is_accepted	True
best_oa_location.is_published	False
best_oa_location.raw_source_name
best_oa_location.landing_page_url	https://doi.org/10.1158/1535-7163.30733948
primary_location.id	doi:10.1158/1535-7163.30733948
primary_location.is_oa	True
primary_location.source
primary_location.license	cc-by
primary_location.pdf_url
primary_location.version	acceptedVersion
primary_location.raw_type	posted-content
primary_location.license_id	https://openalex.org/licenses/cc-by
primary_location.is_accepted	True
primary_location.is_published	False
primary_location.raw_source_name
primary_location.landing_page_url	https://doi.org/10.1158/1535-7163.30733948
publication_date	2025-11-27
publication_year	2025
referenced_works_count	0
abstract_inverted_index.S2	2
abstract_inverted_index.on	6
abstract_inverted_index.its	4
abstract_inverted_index.Fig.	1
abstract_inverted_index.page	7
abstract_inverted_index.with	3
abstract_inverted_index.legend	5
abstract_inverted_index.2</p>	8
abstract_inverted_index.<p>Suppl.	0
cited_by_percentile_year
countries_distinct_count	0
institutions_distinct_count	9
citation_normalized_percentile