Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model Article Swipe

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John Jeffers , Emília M. Pinto , Jerold E. Rehg , Michael R. Clay , Jinling Wang , Geoffrey Neale , Richard J. Heath , Guillermina Lozano , Enzo Lalli , Bonald C. Figueiredo , Alberto S. Pappo , Carlos Rodríguez‐Galindo , Wenan Chen , Stanley Pounds , Raul C. Ribeiro , Gerard P. Zambetti ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1158/0008-5472.22430472

Gene set enrichment analysis of control and IR-treated WT and p53-R334H thymocytes.

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Penetrance Germline Germline mutation Genetics Cancer research Mutation Biology Gene Phenotype

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Type: preprint
Language: en
Landing Page: https://doi.org/10.1158/0008-5472.22430472
OA Status: gold
Related Works: 10
OpenAlex ID: https://openalex.org/W4361839799

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DOI: https://doi.org/10.1158/0008-5472.22430472

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Title: Supplementary Figure S5 from The Common Germline <i>TP53-R337H</i> Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model

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Type: preprint

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Language: en

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Publication year: 2023

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Publication date: 2023-03-31

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Authors: John Jeffers, Emília M. Pinto, Jerold E. Rehg, Michael R. Clay, Jinling Wang, Geoffrey Neale, Richard J. Heath, Guillermina Lozano, Enzo Lalli, Bonald C. Figueiredo, Alberto S. Pappo, Carlos Rodríguez‐Galindo, Wenan Chen, Stanley Pounds, Raul C. Ribeiro, Gerard P. Zambetti

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Landing page: https://doi.org/10.1158/0008-5472.22430472

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Open access: Yes

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OA status: gold

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OA URL: https://doi.org/10.1158/0008-5472.22430472

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Concepts: Penetrance, Germline, Germline mutation, Genetics, Cancer research, Mutation, Biology, Gene, Phenotype

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Cited by: 0

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