Supplementary Figure S7 from SARC028 Samples Reveal an Interplay between TGF-β, IFN Signaling, and Low HLA Class I Expression as Contributors to Ewing Sarcoma Checkpoint Blockade Resistance Article Swipe

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Jessica D. Daley , Elina Mukherjee , David Ferraro , Shanthi Bhaskar , Anthony Green , E. Michael Meyer , Hussein A. Tawbi , Melissa Burgess , Tullia C. Bruno , Anthony R. Cillo , Kelly M. Bailey ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1158/1078-0432.30028540

Supplementary Figure S7. Spatial distribution of cells from each patient tumor biopsy and enumeration of the proportion of cells with in each spatially resolved cell neighborhoods in each biopsy.

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Blockade Ewing's sarcoma Cancer research Transforming growth factor Immune checkpoint Expression (computer science) Sarcoma Biology Cell biology Medicine Genetics Computer science Receptor Pathology Programming language

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Language: en
Landing Page: https://doi.org/10.1158/1078-0432.30028540
PDF: https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_S7_from_SARC028_Samples_Reveal_an_Interplay_between_TGF-_IFN_Signaling_and_Low_HLA_Class_I_Expression_as_Contributors_to_Ewing_Sarcoma_Checkpoint_Blockade_Resistance/30028540/1/files/57576844.pdf
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DOI: https://doi.org/10.1158/1078-0432.30028540

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Title: Supplementary Figure S7 from SARC028 Samples Reveal an Interplay between TGF-β, IFN Signaling, and Low HLA Class I Expression as Contributors to Ewing Sarcoma Checkpoint Blockade Resistance

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Language: en

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Publication year: 2025

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Publication date: 2025-09-02

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Authors: Jessica D. Daley, Elina Mukherjee, David Ferraro, Shanthi Bhaskar, Anthony Green, E. Michael Meyer, Hussein A. Tawbi, Melissa Burgess, Tullia C. Bruno, Anthony R. Cillo, Kelly M. Bailey

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Landing page: https://doi.org/10.1158/1078-0432.30028540

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Concepts: Blockade, Ewing's sarcoma, Cancer research, Transforming growth factor, Immune checkpoint, Expression (computer science), Sarcoma, Biology, Cell biology, Medicine, Genetics, Computer science, Receptor, Pathology, Programming language

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