Supplementary Material for: Cerebellar Superficial Siderosis in Cerebral Amyloid Angiopathy on 1.5T T2*-Weighted Imaging Article Swipe
Dimitri Renard
,
Sabine Laurent‐Chabalier
,
Adelina Leonte
,
Marc Hackius
,
Teodora Parvu
,
Anne Wacongne
,
Éric Thouvenot
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.6084/m9.figshare.22220071
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.6084/m9.figshare.22220071
Background: Cerebellar superficial siderosis (SS) has been recently reported to be present in about 10% of both hereditary and sporadic cerebral amyloid angiopathy (CAA) on 3T MRI using primarily susceptibility-weighted imaging. Objectives: Our aim was to assess cerebellar SS in sporadic CAA patients using 1.5T T2*-weighted MRI and to evaluate possible underlying mechanisms. Method: We retrospectively screened MRI scans of sporadic probable CAA patients initially presenting with intracerebral hemorrhage-, acute subarachnoid hemorrhage- or cortical SS-related symptoms between September 2009 and January 2022 registered in our stroke database. Patients with familial CAA were excluded. On 1.5T T2*-weighted MRI, cerebellar SS (including kappa statistics for interobserver agreement) was assessed together with typical CAA hemorrhagic features and with the presence of supratentorial macrobleed and cortical SS adjacent to the tentorium cerebelli (TC) and TC hemosiderosis. Results: We screened 151 patients and finally included 111 CAA patients (median age 77) with cerebellar SS observed in 6 (5%) patients. Cerebellar SS presence was associated with a higher number of supratentorial macrobleeds (median n = 3 vs. n = 1, p = 0.0012), presence of supratentorial macrobleed adjacent to the TC (p = 0.002), and TC hemosiderosis (p = 0.005). Conclusions: Cerebellar SS in CAA patients can be identified on 1.5T T2*-weighted imaging. Associated MRI characteristics suggest contamination from supratentorial macrobleeds.
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Metadata
- Type
- dataset
- Language
- en
- Landing Page
- https://doi.org/10.6084/m9.figshare.22220071
- OA Status
- gold
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4394335875Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.6084/m9.figshare.22220071Digital Object Identifier
- Title
-
Supplementary Material for: Cerebellar Superficial Siderosis in Cerebral Amyloid Angiopathy on 1.5T T2*-Weighted ImagingWork title
- Type
-
datasetOpenAlex work type
- Language
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enPrimary language
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2023Year of publication
- Publication date
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2023-01-01Full publication date if available
- Authors
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Dimitri Renard, Sabine Laurent‐Chabalier, Adelina Leonte, Marc Hackius, Teodora Parvu, Anne Wacongne, Éric ThouvenotList of authors in order
- Landing page
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https://doi.org/10.6084/m9.figshare.22220071Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.6084/m9.figshare.22220071Direct OA link when available
- Concepts
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Superficial siderosis, Cerebral amyloid angiopathy, Siderosis, Medicine, Amyloid (mycology), Pathology, Dementia, DiseaseTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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