Supplementary Material for: International variability of renal and cardiovascular outcomes and mortality in patients with type 2 diabetes mellitus in Europe Article Swipe
Stefanie Thöni
,
Frieder Keller
,
Sara Denicolò
,
Susanne Eder
,
Lukas Buchwinkler
,
László Rosivall
,
Andrzej Więcek
,
Mark P.B.
,
Peter Rossing
,
Heerspink H.J.L.
,
Gert Mayer
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.6084/m9.figshare.22233337
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.6084/m9.figshare.22233337
Introduction Type 2 diabetes and its complications represent a huge burden to public health. With this prospective, observational cohort study, we aimed to estimate and to compare the incidence rate (IR) of renal and cardiovascular outcomes and all-cause mortality in patients with type 2 diabetes in different European countries. Methods The renal endpoint was a composite of a sustained decline in estimated GFR of at least 40 %, a sustained increase in albuminuria of at least 30 % including a transition in albuminuria class, progression to kidney failure with replacement therapy, or death from renal causes. The cardiovascular endpoint was a composite of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. Results 3131 participants from four European countries (Austria, Hungary, The Netherlands, and Scotland) with a median follow-up time of 4.4 years were included. IRs were adjusted for several risk factors including sex, age, estimated GFR, albuminuria, HbA1c, blood pressure and duration of type 2 diabetes. Across countries, the adjusted IR for the renal endpoint was significantly higher in Hungary and Austria, the adjusted IR for the cardiovascular endpoint was significantly higher in Scotland and Austria. All-cause mortality was significantly higher in Scotland compared to all other countries. Conclusion Our findings show how the longitudinal outcome of patients with type 2 diabetes varies significantly across European countries even after accounting for the distribution of underlying risk factors.
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Concepts
Metadata
- Type
- dataset
- Language
- en
- Landing Page
- https://research.rug.nl/en/datasets/11fb0202-a0a0-4587-be36-4858a49d7781
- OA Status
- green
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All OpenAlex metadata
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https://openalex.org/W4394514728Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.6084/m9.figshare.22233337Digital Object Identifier
- Title
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Supplementary Material for: International variability of renal and cardiovascular outcomes and mortality in patients with type 2 diabetes mellitus in EuropeWork title
- Type
-
datasetOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
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2023-01-01Full publication date if available
- Authors
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Stefanie Thöni, Frieder Keller, Sara Denicolò, Susanne Eder, Lukas Buchwinkler, László Rosivall, Andrzej Więcek, Mark P.B., Peter Rossing, Heerspink H.J.L., Gert MayerList of authors in order
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https://research.rug.nl/en/datasets/11fb0202-a0a0-4587-be36-4858a49d7781Publisher landing page
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greenOpen access status per OpenAlex
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https://research.rug.nl/en/datasets/11fb0202-a0a0-4587-be36-4858a49d7781Direct OA link when available
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Medicine, Diabetes mellitus, Type 2 Diabetes Mellitus, Internal medicine, Type 2 diabetes, Cardiology, Demography, Intensive care medicine, Endocrinology, SociologyTop concepts (fields/topics) attached by OpenAlex
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| abstract_inverted_index.Austria, | 173 |
| abstract_inverted_index.Austria. | 187 |
| abstract_inverted_index.European | 47, 118, 217 |
| abstract_inverted_index.Hungary, | 121 |
| abstract_inverted_index.Scotland | 185, 194 |
| abstract_inverted_index.adjusted | 138, 161, 175 |
| abstract_inverted_index.compared | 195 |
| abstract_inverted_index.diabetes | 3, 44, 213 |
| abstract_inverted_index.duration | 153 |
| abstract_inverted_index.endpoint | 52, 98, 166, 180 |
| abstract_inverted_index.estimate | 23 |
| abstract_inverted_index.factors. | 228 |
| abstract_inverted_index.findings | 202 |
| abstract_inverted_index.increase | 70 |
| abstract_inverted_index.nonfatal | 107, 111 |
| abstract_inverted_index.outcomes | 35 |
| abstract_inverted_index.patients | 40, 209 |
| abstract_inverted_index.pressure | 151 |
| abstract_inverted_index.therapy, | 90 |
| abstract_inverted_index.(Austria, | 120 |
| abstract_inverted_index.All-cause | 188 |
| abstract_inverted_index.Scotland) | 125 |
| abstract_inverted_index.all-cause | 37 |
| abstract_inverted_index.composite | 55, 101 |
| abstract_inverted_index.countries | 119, 218 |
| abstract_inverted_index.diabetes. | 157 |
| abstract_inverted_index.different | 46 |
| abstract_inverted_index.estimated | 61, 146 |
| abstract_inverted_index.follow-up | 129 |
| abstract_inverted_index.incidence | 28 |
| abstract_inverted_index.included. | 135 |
| abstract_inverted_index.including | 78, 143 |
| abstract_inverted_index.mortality | 38, 189 |
| abstract_inverted_index.represent | 7 |
| abstract_inverted_index.sustained | 58, 69 |
| abstract_inverted_index.Conclusion | 200 |
| abstract_inverted_index.accounting | 221 |
| abstract_inverted_index.countries, | 159 |
| abstract_inverted_index.countries. | 48, 199 |
| abstract_inverted_index.myocardial | 108 |
| abstract_inverted_index.transition | 80 |
| abstract_inverted_index.underlying | 226 |
| abstract_inverted_index.albuminuria | 72, 82 |
| abstract_inverted_index.infarction, | 109 |
| abstract_inverted_index.progression | 84 |
| abstract_inverted_index.replacement | 89 |
| abstract_inverted_index.Introduction | 0 |
| abstract_inverted_index.Netherlands, | 123 |
| abstract_inverted_index.albuminuria, | 148 |
| abstract_inverted_index.distribution | 224 |
| abstract_inverted_index.longitudinal | 206 |
| abstract_inverted_index.participants | 115 |
| abstract_inverted_index.prospective, | 16 |
| abstract_inverted_index.complications | 6 |
| abstract_inverted_index.observational | 17 |
| abstract_inverted_index.significantly | 168, 182, 191, 215 |
| abstract_inverted_index.cardiovascular | 34, 97, 105, 179 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 11 |
| citation_normalized_percentile |