Supplementary Tables S1-S4 from <i>IRS2</i> Copy Number Gain, <i>KRAS</i> and <i>BRAF</i> Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines Article Swipe
Fei Huang
,
Han Chang
,
Ann Greer
,
Stephen Hillerman
,
Karen A. Reeves
,
Warren Hurlburt
,
John Cogswell
,
Dharmesh Patel
,
Zhenhao Qi
,
Craig R. Fairchild
,
Rolf-Peter Ryseck
,
Tai W. Wong
,
Friedrich Graf Finckenstein
,
Jeffrey L. Jackson
,
Joan M. Carboni
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1158/1535-7163.22503652
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1158/1535-7163.22503652
Supplementary Tables S1-S4. Supplementary Table S1: Association of gene mutations, IRS2 copy number gain, and gene expression level with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S2: The relationship between KRAS, BRAF and PIK3CA mutation status and the sensitivity of BMS-754807 in 60 CRC cell lines. Supplementary Table S3: Statistical analyses identified CNV of 197 genes located on chromosome 13 significantly associated with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S4: Data mining indicate IRS2 CNG is more prevalent in CRC than in other tumor types.
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- https://doi.org/10.1158/1535-7163.22503652
- OA Status
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https://doi.org/10.1158/1535-7163.22503652Digital Object Identifier
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Supplementary Tables S1-S4 from <i>IRS2</i> Copy Number Gain, <i>KRAS</i> and <i>BRAF</i> Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell LinesWork title
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supplementary-materialsOpenAlex work type
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2023Year of publication
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2023-04-03Full publication date if available
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Fei Huang, Han Chang, Ann Greer, Stephen Hillerman, Karen A. Reeves, Warren Hurlburt, John Cogswell, Dharmesh Patel, Zhenhao Qi, Craig R. Fairchild, Rolf-Peter Ryseck, Tai W. Wong, Friedrich Graf Finckenstein, Jeffrey L. Jackson, Joan M. CarboniList of authors in order
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https://doi.org/10.1158/1535-7163.22503652Publisher landing page
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goldOpen access status per OpenAlex
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KRAS, Gene, Mutation, Biology, Cancer research, GeneticsTop concepts (fields/topics) attached by OpenAlex
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