Supplementation of Mother’s Own Milk with Donor Milk in Infants with Gastroschisis or Intestinal Atresia: A Retrospective Study Article Swipe

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Rebecca Hoban , Supriya Khatri , Aloka L. Patel , Sharon Unger ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.3390/nu12020589

Background: Mother’s own milk (MOM) improves in-hospital outcomes for preterm infants. If unavailable, donor milk (DM) is often substituted. It is unclear if DM vs. formula to supplement MOM is associated with improved in-hospital outcomes in term/late preterm surgical infants with gastroschisis or intestinal atresia. Methods: This retrospective study included infants born ≥33 weeks gestational age (GA) with a birth weight of >1500 g who were admitted to a quaternary neonatal intensive care unit (NICU). Using Chi square and Mann-Whitney u testing, we compared hospital outcomes (length of stay, parenteral nutrition and central line days) before and after a clinical practice change to offer DM instead of formula in this surgical population. Results: Baseline characteristics were similar between eras for the 140 infants (median GA 37 weeks). Fewer infants in DM era were receiving formula at discharge (50.0% vs. 31.4%, p = 0.03). In sub-analyses including only small bowel atresia and gastroschisis infants, the median length of stay (35 vs. 25, p < 0.01) and the central line days (28 vs. 20, p < 0.01) were lower in the DM era. Conclusion: In this retrospective study, offering DM instead of formula was associated with less formula feeding at discharge, and in infants with gastroschisis or small bowel atresia, shorter length of stay and central line days.

Related Topics

Neonatal Intensive Care Unit

Concepts

Gastroschisis Medicine Gestational age Retrospective cohort study Pediatrics Intestinal atresia Parenteral nutrition Atresia Neonatal intensive care unit Birth weight Short bowel syndrome Infant formula Population Necrotizing enterocolitis Obstetrics Pregnancy Fetus Surgery Biology Genetics Environmental health

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Type: article
Language: en
Landing Page: https://doi.org/10.3390/nu12020589
PDF: https://www.mdpi.com/2072-6643/12/2/589/pdf?version=1582543407
OA Status: gold
Cited By: 33
References: 31
Related Works: 10
OpenAlex ID: https://openalex.org/W3008749504

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OpenAlex ID: https://openalex.org/W3008749504

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DOI: https://doi.org/10.3390/nu12020589

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Title: Supplementation of Mother’s Own Milk with Donor Milk in Infants with Gastroschisis or Intestinal Atresia: A Retrospective Study

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Type: article

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Language: en

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Publication year: 2020

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Publication date: 2020-02-24

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Authors: Rebecca Hoban, Supriya Khatri, Aloka L. Patel, Sharon Unger

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Landing page: https://doi.org/10.3390/nu12020589

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PDF URL: https://www.mdpi.com/2072-6643/12/2/589/pdf?version=1582543407

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Concepts: Gastroschisis, Medicine, Gestational age, Retrospective cohort study, Pediatrics, Intestinal atresia, Parenteral nutrition, Atresia, Neonatal intensive care unit, Birth weight, Short bowel syndrome, Infant formula, Population, Necrotizing enterocolitis, Obstetrics, Pregnancy, Fetus, Surgery, Biology, Genetics, Environmental health

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Cited by: 33

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Citations by year (recent): 2025: 4, 2024: 9, 2023: 9, 2022: 5, 2021: 4

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Related works (count): 10

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