Journal of the American Heart Association • Vol 11 • No 10
Surgical Timing in Patients With Infective Endocarditis and With Intracranial Hemorrhage: A Systematic Review and Meta‐Analysis
May 2022 • Rita Musleh, Peter Schlattmann, Túlio Caldonazo, Hristo Kirov, Otto W. Witte, Torsten Doenst, Albrecht Günther, Mahmoud Diab
Background Intracranial hemorrhage (ICH) is one of the main causes for lack of surgery in patients with infective endocarditis (IE), despite the presence of surgical indications. We aimed to evaluate the impact of early surgery in patients with IE and with ICH on postoperative neurological deterioration and all‐cause mortality and to elucidate the risk of 30‐day mortality in patients who were denied surgery. Methods and Results Three libraries (MEDLINE, EMBASE, and Cochrane Library) were assessed. The primary outc…