Synthesis of potential pharmaceutically active dihydropyrimidine-2-oxo and their 2-thio analogues Article Swipe
Related Concepts
Thiourea
Thio-
Biginelli reaction
Urea
Chemistry
Catalysis
Organic chemistry
Component (thermodynamics)
Combinatorial chemistry
Physics
Thermodynamics
ME Halim
,
Kawsari Akhter
,
Md. Kamrul Hasan
,
MM Rahman
,
UKR Romman
,
MG Ahmed
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3329/bjsir.v53i4.39198
· OA: W2905335910
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3329/bjsir.v53i4.39198
· OA: W2905335910
The Biginelli one - pot three-component cyclocondensation was applied to prepare 3, 4 - dihydropyrimidin - 2 (1H) – ones from aldehydes, β-dicarbonyl compounds and urea (or thiourea) using ZnCl2 as a catalyst. The method offers several advantages including short reaction times and easy experimental work up procedures.Bangladesh J. Sci. Ind. Res.53(4), 327-332, 2018
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