Synthesis, Structure Characterization, and Antimicrobial Activity of 2-Amino-3-[(2-Amino-2-Carboxyethyl) Disulfanyl] Propanoic Acid Dihydrogen Triiodide Coordination Compound Article Swipe
Seitzhan Turganbay
,
Aleksandr I. Ilin
,
Nelly Atageldiyeva
,
Аrdak Jumagaziyeva
,
Sabina T. Kenesheva
,
Gulshat Baigaipova
,
S. Mun
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.30919/es956
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.30919/es956
The aim of this study was the synthesis of iodine coordination compounds for the treatment of nosocomial infections caused by drug-resistant bacteria.A new 2-amino-3-[(2-amino-2carboxyethyl) disulfanyl] propanoic acid dihydrogen triiodide coordination compound was synthesized in basic and water media with a stoichiometric ratio of 1:2:2 of Cystine:LiI:iodine.The physico-chemical properties of complex 2-amino-3-[(2-amino-2-carboxyethyl) disulfanyl] propanoic acid dihydrogen triiodide were examined.Obtained crystals were studied by singlecrystal X-ray diffraction, FTIR spectroscopy, UV-Vis spectrophotometer and Thermogravimetry/Differential Scanning Colorimeter (TG/DSC).The compound crystallizes in the orthorhombic P212121 with lattice parameters a = 9.5739(19) Å, b = 13.558(3)Å, c = 16.405(3)Å, α = 90, β = 90, = 90, V = 2129.4(7)Å 3 ; Z = 4.The antimicrobial activity of the synthesized compound was investigated.Activity evaluations were done against ATCC bacterial and clinical isolates, including WHO-prioritised drug-resistant strains.In the study, the effectiveness of a new coordination compound of iodine against bacteria with multidrug resistance was shown.This fact, as well as the semi-organic nature of the compound, determinethe prospects for its use in medicine as an antimicrobial agent.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.30919/es956
- https://www.espublisher.com/uploads/article_pdf/es956_JustAccepted.pdf
- OA Status
- bronze
- Cited By
- 6
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4386585464
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- OpenAlex ID
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https://openalex.org/W4386585464Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.30919/es956Digital Object Identifier
- Title
-
Synthesis, Structure Characterization, and Antimicrobial Activity of 2-Amino-3-[(2-Amino-2-Carboxyethyl) Disulfanyl] Propanoic Acid Dihydrogen Triiodide Coordination CompoundWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
-
2023-01-01Full publication date if available
- Authors
-
Seitzhan Turganbay, Aleksandr I. Ilin, Nelly Atageldiyeva, Аrdak Jumagaziyeva, Sabina T. Kenesheva, Gulshat Baigaipova, S. MunList of authors in order
- Landing page
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https://doi.org/10.30919/es956Publisher landing page
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https://www.espublisher.com/uploads/article_pdf/es956_JustAccepted.pdfDirect link to full text PDF
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://www.espublisher.com/uploads/article_pdf/es956_JustAccepted.pdfDirect OA link when available
- Concepts
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Triiodide, Chemistry, Propanoic acid, Coordination complex, Crystal structure, Orthorhombic crystal system, Amino acid, Stereochemistry, Medicinal chemistry, Crystallography, Organic chemistry, Metal, Biochemistry, Physical chemistry, Electrolyte, Dye-sensitized solar cell, ElectrodeTop concepts (fields/topics) attached by OpenAlex
- Cited by
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6Total citation count in OpenAlex
- Citations by year (recent)
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2025: 3, 2024: 1, 2023: 2Per-year citation counts (last 5 years)
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36Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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