Systematic identification of CAZymes and transcription factors in the hypercellulolytic fungus Penicillium funiculosum NCIM1228 involved in lignocellulosic biomass degradation Article Swipe
Nandita Pasari
,
Mayank Gupta
,
Tulika Sinha
,
Funso Emmanuel Ogunmolu
,
Syed Shams Yazdani
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1186/s13068-023-02399-9
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1186/s13068-023-02399-9
Background Penicillium funiculosum NCIM1228 is a filamentous fungus that was identified in our laboratory to have high cellulolytic activity. Analysis of its secretome suggested that it responds to different carbon substrates by secreting specific enzymes capable of digesting those substrates. This phenomenon indicated the presence of a regulatory system guiding the expression of these hydrolyzing enzymes. Since transcription factors (TFs) are the key players in regulating the expression of enzymes, this study aimed first to identify the complete repertoire of Carbohydrate Active Enzymes (CAZymes) and TFs coded in its genome. The regulation of CAZymes was then analysed by studying the expression pattern of these CAZymes and TFs in different carbon substrates—Avicel (cellulosic substrate), wheat bran (WB; hemicellulosic substrate), Avicel + wheat bran, pre-treated wheat straw (a potential substrate for lignocellulosic ethanol), and glucose (control). Results The P. funiculosum NCIM1228 genome was sequenced, and 10,739 genes were identified in its genome. These genes included a total of 298 CAZymes and 451 TF coding genes. A distinct expression pattern of the CAZymes was observed in different carbon substrates tested. Core cellulose hydrolyzing enzymes were highly expressed in the presence of Avicel, while pre-treated wheat straw and Avicel + wheat bran induced a mixture of CAZymes because of their heterogeneous nature. Wheat bran mainly induced hemicellulases, and the least number of CAZymes were expressed in glucose. TFs also exhibited distinct expression patterns in each of the carbon substrates. Though most of these TFs have not been functionally characterized before, homologs of NosA, Fcr1, and ATF21, which have been known to be involved in fruiting body development, protein secretion and stress response, were identified. Conclusions Overall, the P. funiculosum NCIM1228 genome was sequenced, and the CAZymes and TFs present in its genome were annotated. The expression of the CAZymes and TFs in response to various polymeric sugars present in the lignocellulosic biomass was identified. This work thus provides a comprehensive mapping of transcription factors (TFs) involved in regulating the production of biomass hydrolyzing enzymes.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s13068-023-02399-9
- https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9
- OA Status
- gold
- Cited By
- 11
- References
- 54
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4387330875
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4387330875Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s13068-023-02399-9Digital Object Identifier
- Title
-
Systematic identification of CAZymes and transcription factors in the hypercellulolytic fungus Penicillium funiculosum NCIM1228 involved in lignocellulosic biomass degradationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-10-04Full publication date if available
- Authors
-
Nandita Pasari, Mayank Gupta, Tulika Sinha, Funso Emmanuel Ogunmolu, Syed Shams YazdaniList of authors in order
- Landing page
-
https://doi.org/10.1186/s13068-023-02399-9Publisher landing page
- PDF URL
-
https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9Direct OA link when available
- Concepts
-
Biology, Bran, Gene, Genome, Fungus, Enzyme, Biochemistry, Microbiology, Botany, Raw material, EcologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
11Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 5, 2024: 6Per-year citation counts (last 5 years)
- References (count)
-
54Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4387330875 |
|---|---|
| doi | https://doi.org/10.1186/s13068-023-02399-9 |
| ids.doi | https://doi.org/10.1186/s13068-023-02399-9 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/37794424 |
| ids.openalex | https://openalex.org/W4387330875 |
| fwci | 1.74765855 |
| type | article |
| title | Systematic identification of CAZymes and transcription factors in the hypercellulolytic fungus Penicillium funiculosum NCIM1228 involved in lignocellulosic biomass degradation |
| awards[0].id | https://openalex.org/G5882455545 |
| awards[0].funder_id | https://openalex.org/F4320320717 |
| awards[0].display_name | |
| awards[0].funder_award_id | BT/PR/Centre/03/2011-Phase II |
| awards[0].funder_display_name | Department of Biotechnology, Ministry of Science and Technology, India |
| biblio.issue | 1 |
| biblio.volume | 16 |
| biblio.last_page | 150 |
| biblio.first_page | 150 |
| topics[0].id | https://openalex.org/T10171 |
| topics[0].field.id | https://openalex.org/fields/22 |
| topics[0].field.display_name | Engineering |
| topics[0].score | 0.9998000264167786 |
| topics[0].domain.id | https://openalex.org/domains/3 |
| topics[0].domain.display_name | Physical Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2204 |
| topics[0].subfield.display_name | Biomedical Engineering |
| topics[0].display_name | Biofuel production and bioconversion |
| topics[1].id | https://openalex.org/T10497 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.996399998664856 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Fungal and yeast genetics research |
| topics[2].id | https://openalex.org/T10932 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9958000183105469 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | Microbial Metabolic Engineering and Bioproduction |
| funders[0].id | https://openalex.org/F4320320717 |
| funders[0].ror | https://ror.org/03tjsyq23 |
| funders[0].display_name | Department of Biotechnology, Ministry of Science and Technology, India |
| is_xpac | False |
| apc_list.value | 1990 |
| apc_list.currency | GBP |
| apc_list.value_usd | 2440 |
| apc_paid.value | 1990 |
| apc_paid.currency | GBP |
| apc_paid.value_usd | 2440 |
| concepts[0].id | https://openalex.org/C86803240 |
| concepts[0].level | 0 |
| concepts[0].score | 0.8130189776420593 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[0].display_name | Biology |
| concepts[1].id | https://openalex.org/C2776873940 |
| concepts[1].level | 3 |
| concepts[1].score | 0.6609496474266052 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q188672 |
| concepts[1].display_name | Bran |
| concepts[2].id | https://openalex.org/C104317684 |
| concepts[2].level | 2 |
| concepts[2].score | 0.5358484983444214 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[2].display_name | Gene |
| concepts[3].id | https://openalex.org/C141231307 |
| concepts[3].level | 3 |
| concepts[3].score | 0.5172001123428345 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q7020 |
| concepts[3].display_name | Genome |
| concepts[4].id | https://openalex.org/C2779678110 |
| concepts[4].level | 2 |
| concepts[4].score | 0.44492650032043457 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q764 |
| concepts[4].display_name | Fungus |
| concepts[5].id | https://openalex.org/C181199279 |
| concepts[5].level | 2 |
| concepts[5].score | 0.4137158691883087 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q8047 |
| concepts[5].display_name | Enzyme |
| concepts[6].id | https://openalex.org/C55493867 |
| concepts[6].level | 1 |
| concepts[6].score | 0.3470969796180725 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q7094 |
| concepts[6].display_name | Biochemistry |
| concepts[7].id | https://openalex.org/C89423630 |
| concepts[7].level | 1 |
| concepts[7].score | 0.32459554076194763 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7193 |
| concepts[7].display_name | Microbiology |
| concepts[8].id | https://openalex.org/C59822182 |
| concepts[8].level | 1 |
| concepts[8].score | 0.255132794380188 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q441 |
| concepts[8].display_name | Botany |
| concepts[9].id | https://openalex.org/C206139338 |
| concepts[9].level | 2 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q192355 |
| concepts[9].display_name | Raw material |
| concepts[10].id | https://openalex.org/C18903297 |
| concepts[10].level | 1 |
| concepts[10].score | 0.0 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q7150 |
| concepts[10].display_name | Ecology |
| keywords[0].id | https://openalex.org/keywords/biology |
| keywords[0].score | 0.8130189776420593 |
| keywords[0].display_name | Biology |
| keywords[1].id | https://openalex.org/keywords/bran |
| keywords[1].score | 0.6609496474266052 |
| keywords[1].display_name | Bran |
| keywords[2].id | https://openalex.org/keywords/gene |
| keywords[2].score | 0.5358484983444214 |
| keywords[2].display_name | Gene |
| keywords[3].id | https://openalex.org/keywords/genome |
| keywords[3].score | 0.5172001123428345 |
| keywords[3].display_name | Genome |
| keywords[4].id | https://openalex.org/keywords/fungus |
| keywords[4].score | 0.44492650032043457 |
| keywords[4].display_name | Fungus |
| keywords[5].id | https://openalex.org/keywords/enzyme |
| keywords[5].score | 0.4137158691883087 |
| keywords[5].display_name | Enzyme |
| keywords[6].id | https://openalex.org/keywords/biochemistry |
| keywords[6].score | 0.3470969796180725 |
| keywords[6].display_name | Biochemistry |
| keywords[7].id | https://openalex.org/keywords/microbiology |
| keywords[7].score | 0.32459554076194763 |
| keywords[7].display_name | Microbiology |
| keywords[8].id | https://openalex.org/keywords/botany |
| keywords[8].score | 0.255132794380188 |
| keywords[8].display_name | Botany |
| language | en |
| locations[0].id | doi:10.1186/s13068-023-02399-9 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4210233465 |
| locations[0].source.issn | 2731-3654 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2731-3654 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Biotechnology for Biofuels and Bioproducts |
| locations[0].source.host_organization | https://openalex.org/P4310320256 |
| locations[0].source.host_organization_name | BioMed Central |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320256, https://openalex.org/P4310319965 |
| locations[0].source.host_organization_lineage_names | BioMed Central, Springer Nature |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Biotechnology for Biofuels and Bioproducts |
| locations[0].landing_page_url | https://doi.org/10.1186/s13068-023-02399-9 |
| locations[1].id | pmid:37794424 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Biotechnology for biofuels and bioproducts |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/37794424 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:10552389 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | cc-by |
| locations[2].pdf_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10552389/pdf/13068_2023_Article_2399.pdf |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/cc-by |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Biotechnol Biofuels Bioprod |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/10552389 |
| locations[3].id | pmh:oai:doaj.org/article:48ca167987e34929b730b7efaa959bae |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-18 (2023) |
| locations[3].landing_page_url | https://doaj.org/article/48ca167987e34929b730b7efaa959bae |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5059017416 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Nandita Pasari |
| authorships[0].countries | IN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210142124 |
| authorships[0].affiliations[0].raw_affiliation_string | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[0].institutions[0].id | https://openalex.org/I4210142124 |
| authorships[0].institutions[0].ror | https://ror.org/03j4rrt43 |
| authorships[0].institutions[0].type | facility |
| authorships[0].institutions[0].lineage | https://openalex.org/I4210142124, https://openalex.org/I91080651 |
| authorships[0].institutions[0].country_code | IN |
| authorships[0].institutions[0].display_name | International Centre for Genetic Engineering and Biotechnology |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Nandita Pasari |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[1].author.id | https://openalex.org/A5101426244 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-4151-3393 |
| authorships[1].author.display_name | Mayank Gupta |
| authorships[1].countries | IN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210142124 |
| authorships[1].affiliations[0].raw_affiliation_string | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[1].institutions[0].id | https://openalex.org/I4210142124 |
| authorships[1].institutions[0].ror | https://ror.org/03j4rrt43 |
| authorships[1].institutions[0].type | facility |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210142124, https://openalex.org/I91080651 |
| authorships[1].institutions[0].country_code | IN |
| authorships[1].institutions[0].display_name | International Centre for Genetic Engineering and Biotechnology |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Mayank Gupta |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[2].author.id | https://openalex.org/A5026970014 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Tulika Sinha |
| authorships[2].countries | IN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210142124 |
| authorships[2].affiliations[0].raw_affiliation_string | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[2].institutions[0].id | https://openalex.org/I4210142124 |
| authorships[2].institutions[0].ror | https://ror.org/03j4rrt43 |
| authorships[2].institutions[0].type | facility |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210142124, https://openalex.org/I91080651 |
| authorships[2].institutions[0].country_code | IN |
| authorships[2].institutions[0].display_name | International Centre for Genetic Engineering and Biotechnology |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Tulika Sinha |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[3].author.id | https://openalex.org/A5067227317 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-0558-4626 |
| authorships[3].author.display_name | Funso Emmanuel Ogunmolu |
| authorships[3].countries | IN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210142124 |
| authorships[3].affiliations[0].raw_affiliation_string | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[3].institutions[0].id | https://openalex.org/I4210142124 |
| authorships[3].institutions[0].ror | https://ror.org/03j4rrt43 |
| authorships[3].institutions[0].type | facility |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210142124, https://openalex.org/I91080651 |
| authorships[3].institutions[0].country_code | IN |
| authorships[3].institutions[0].display_name | International Centre for Genetic Engineering and Biotechnology |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Funso Emmanuel Ogunmolu |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[4].author.id | https://openalex.org/A5058911046 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-6558-4612 |
| authorships[4].author.display_name | Syed Shams Yazdani |
| authorships[4].countries | IN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210142124 |
| authorships[4].affiliations[0].raw_affiliation_string | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| authorships[4].institutions[0].id | https://openalex.org/I4210142124 |
| authorships[4].institutions[0].ror | https://ror.org/03j4rrt43 |
| authorships[4].institutions[0].type | facility |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210142124, https://openalex.org/I91080651 |
| authorships[4].institutions[0].country_code | IN |
| authorships[4].institutions[0].display_name | International Centre for Genetic Engineering and Biotechnology |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Syed Shams Yazdani |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Microbial Engineering Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Systematic identification of CAZymes and transcription factors in the hypercellulolytic fungus Penicillium funiculosum NCIM1228 involved in lignocellulosic biomass degradation |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10171 |
| primary_topic.field.id | https://openalex.org/fields/22 |
| primary_topic.field.display_name | Engineering |
| primary_topic.score | 0.9998000264167786 |
| primary_topic.domain.id | https://openalex.org/domains/3 |
| primary_topic.domain.display_name | Physical Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2204 |
| primary_topic.subfield.display_name | Biomedical Engineering |
| primary_topic.display_name | Biofuel production and bioconversion |
| related_works | https://openalex.org/W2999856628, https://openalex.org/W2410176219, https://openalex.org/W2357370727, https://openalex.org/W2410505965, https://openalex.org/W4385632345, https://openalex.org/W2615697344, https://openalex.org/W2421497942, https://openalex.org/W4289349585, https://openalex.org/W2145058723, https://openalex.org/W2130897584 |
| cited_by_count | 11 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 5 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 6 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1186/s13068-023-02399-9 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4210233465 |
| best_oa_location.source.issn | 2731-3654 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2731-3654 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Biotechnology for Biofuels and Bioproducts |
| best_oa_location.source.host_organization | https://openalex.org/P4310320256 |
| best_oa_location.source.host_organization_name | BioMed Central |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320256, https://openalex.org/P4310319965 |
| best_oa_location.source.host_organization_lineage_names | BioMed Central, Springer Nature |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Biotechnology for Biofuels and Bioproducts |
| best_oa_location.landing_page_url | https://doi.org/10.1186/s13068-023-02399-9 |
| primary_location.id | doi:10.1186/s13068-023-02399-9 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4210233465 |
| primary_location.source.issn | 2731-3654 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2731-3654 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Biotechnology for Biofuels and Bioproducts |
| primary_location.source.host_organization | https://openalex.org/P4310320256 |
| primary_location.source.host_organization_name | BioMed Central |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320256, https://openalex.org/P4310319965 |
| primary_location.source.host_organization_lineage_names | BioMed Central, Springer Nature |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://biotechnologyforbiofuels.biomedcentral.com/counter/pdf/10.1186/s13068-023-02399-9 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Biotechnology for Biofuels and Bioproducts |
| primary_location.landing_page_url | https://doi.org/10.1186/s13068-023-02399-9 |
| publication_date | 2023-10-04 |
| publication_year | 2023 |
| referenced_works | https://openalex.org/W1500265862, https://openalex.org/W2033012176, https://openalex.org/W2164072362, https://openalex.org/W6683954254, https://openalex.org/W2018315914, https://openalex.org/W2995454809, https://openalex.org/W2801555871, https://openalex.org/W3081073041, https://openalex.org/W1788645855, https://openalex.org/W2091513159, https://openalex.org/W2108929776, https://openalex.org/W2137690603, https://openalex.org/W4211221678, https://openalex.org/W6809039371, https://openalex.org/W2419653649, https://openalex.org/W2165574256, https://openalex.org/W1144300203, https://openalex.org/W2791907545, https://openalex.org/W2157013134, https://openalex.org/W2130695937, https://openalex.org/W2013050172, https://openalex.org/W2076613576, https://openalex.org/W4242460404, https://openalex.org/W1999634015, https://openalex.org/W2796629542, https://openalex.org/W2620237436, https://openalex.org/W2101786683, https://openalex.org/W2100450322, https://openalex.org/W3217216416, https://openalex.org/W2103539617, https://openalex.org/W2124479692, https://openalex.org/W2159269304, https://openalex.org/W2319486179, https://openalex.org/W2162595238, https://openalex.org/W3091850029, https://openalex.org/W2131310501, https://openalex.org/W2051720620, https://openalex.org/W2942247763, https://openalex.org/W2541917906, https://openalex.org/W2597732583, https://openalex.org/W3175810487, https://openalex.org/W3161441714, https://openalex.org/W2153680746, https://openalex.org/W2134809769, https://openalex.org/W1492436432, https://openalex.org/W2110508830, https://openalex.org/W2153545659, https://openalex.org/W7073547909, https://openalex.org/W2109440294, https://openalex.org/W2148467946, https://openalex.org/W2168292723, https://openalex.org/W2166820820, https://openalex.org/W4225344805, https://openalex.org/W2256925405 |
| referenced_works_count | 54 |
| abstract_inverted_index.+ | 120, 196 |
| abstract_inverted_index.A | 164 |
| abstract_inverted_index.a | 6, 47, 154, 200, 315 |
| abstract_inverted_index.(a | 126 |
| abstract_inverted_index.P. | 137, 274 |
| abstract_inverted_index.TF | 161 |
| abstract_inverted_index.be | 258 |
| abstract_inverted_index.by | 32, 98 |
| abstract_inverted_index.in | 12, 65, 88, 108, 148, 173, 185, 222, 230, 260, 286, 298, 305, 323 |
| abstract_inverted_index.is | 5 |
| abstract_inverted_index.it | 26 |
| abstract_inverted_index.of | 21, 37, 46, 53, 69, 80, 93, 103, 156, 168, 188, 202, 205, 218, 232, 238, 248, 293, 318, 327 |
| abstract_inverted_index.to | 15, 28, 75, 257, 300 |
| abstract_inverted_index.298 | 157 |
| abstract_inverted_index.451 | 160 |
| abstract_inverted_index.TFs | 86, 107, 224, 240, 284, 297 |
| abstract_inverted_index.The | 91, 136, 291 |
| abstract_inverted_index.and | 85, 106, 132, 143, 159, 194, 214, 251, 266, 280, 283, 296 |
| abstract_inverted_index.are | 61 |
| abstract_inverted_index.for | 129 |
| abstract_inverted_index.its | 22, 89, 149, 287 |
| abstract_inverted_index.key | 63 |
| abstract_inverted_index.not | 242 |
| abstract_inverted_index.our | 13 |
| abstract_inverted_index.the | 44, 51, 62, 67, 77, 100, 169, 186, 215, 233, 273, 281, 294, 306, 325 |
| abstract_inverted_index.was | 10, 95, 141, 171, 278, 309 |
| abstract_inverted_index.(WB; | 116 |
| abstract_inverted_index.Core | 178 |
| abstract_inverted_index.This | 41, 311 |
| abstract_inverted_index.also | 225 |
| abstract_inverted_index.been | 243, 255 |
| abstract_inverted_index.body | 262 |
| abstract_inverted_index.bran | 115, 198, 210 |
| abstract_inverted_index.each | 231 |
| abstract_inverted_index.have | 16, 241, 254 |
| abstract_inverted_index.high | 17 |
| abstract_inverted_index.most | 237 |
| abstract_inverted_index.that | 9, 25 |
| abstract_inverted_index.then | 96 |
| abstract_inverted_index.this | 71 |
| abstract_inverted_index.thus | 313 |
| abstract_inverted_index.were | 146, 182, 220, 269, 289 |
| abstract_inverted_index.work | 312 |
| abstract_inverted_index.(TFs) | 60, 321 |
| abstract_inverted_index.Fcr1, | 250 |
| abstract_inverted_index.NosA, | 249 |
| abstract_inverted_index.Since | 57 |
| abstract_inverted_index.These | 151 |
| abstract_inverted_index.Wheat | 209 |
| abstract_inverted_index.aimed | 73 |
| abstract_inverted_index.bran, | 122 |
| abstract_inverted_index.coded | 87 |
| abstract_inverted_index.first | 74 |
| abstract_inverted_index.genes | 145, 152 |
| abstract_inverted_index.known | 256 |
| abstract_inverted_index.least | 216 |
| abstract_inverted_index.straw | 125, 193 |
| abstract_inverted_index.study | 72 |
| abstract_inverted_index.their | 206 |
| abstract_inverted_index.these | 54, 104, 239 |
| abstract_inverted_index.those | 39 |
| abstract_inverted_index.total | 155 |
| abstract_inverted_index.wheat | 114, 121, 124, 192, 197 |
| abstract_inverted_index.which | 253 |
| abstract_inverted_index.while | 190 |
| abstract_inverted_index.10,739 | 144 |
| abstract_inverted_index.ATF21, | 252 |
| abstract_inverted_index.Active | 82 |
| abstract_inverted_index.Avicel | 119, 195 |
| abstract_inverted_index.Though | 236 |
| abstract_inverted_index.carbon | 30, 110, 175, 234 |
| abstract_inverted_index.coding | 162 |
| abstract_inverted_index.fungus | 8 |
| abstract_inverted_index.genes. | 163 |
| abstract_inverted_index.genome | 140, 277, 288 |
| abstract_inverted_index.highly | 183 |
| abstract_inverted_index.mainly | 211 |
| abstract_inverted_index.number | 217 |
| abstract_inverted_index.stress | 267 |
| abstract_inverted_index.sugars | 303 |
| abstract_inverted_index.system | 49 |
| abstract_inverted_index.Avicel, | 189 |
| abstract_inverted_index.CAZymes | 94, 105, 158, 170, 203, 219, 282, 295 |
| abstract_inverted_index.Enzymes | 83 |
| abstract_inverted_index.Results | 135 |
| abstract_inverted_index.because | 204 |
| abstract_inverted_index.before, | 246 |
| abstract_inverted_index.biomass | 308, 328 |
| abstract_inverted_index.capable | 36 |
| abstract_inverted_index.enzymes | 35, 181 |
| abstract_inverted_index.factors | 59, 320 |
| abstract_inverted_index.genome. | 90, 150 |
| abstract_inverted_index.glucose | 133 |
| abstract_inverted_index.guiding | 50 |
| abstract_inverted_index.induced | 199, 212 |
| abstract_inverted_index.mapping | 317 |
| abstract_inverted_index.mixture | 201 |
| abstract_inverted_index.nature. | 208 |
| abstract_inverted_index.pattern | 102, 167 |
| abstract_inverted_index.players | 64 |
| abstract_inverted_index.present | 285, 304 |
| abstract_inverted_index.protein | 264 |
| abstract_inverted_index.tested. | 177 |
| abstract_inverted_index.various | 301 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Analysis | 20 |
| abstract_inverted_index.NCIM1228 | 4, 139, 276 |
| abstract_inverted_index.Overall, | 272 |
| abstract_inverted_index.analysed | 97 |
| abstract_inverted_index.complete | 78 |
| abstract_inverted_index.distinct | 165, 227 |
| abstract_inverted_index.enzymes, | 70 |
| abstract_inverted_index.enzymes. | 56, 330 |
| abstract_inverted_index.fruiting | 261 |
| abstract_inverted_index.glucose. | 223 |
| abstract_inverted_index.homologs | 247 |
| abstract_inverted_index.identify | 76 |
| abstract_inverted_index.included | 153 |
| abstract_inverted_index.involved | 259, 322 |
| abstract_inverted_index.observed | 172 |
| abstract_inverted_index.patterns | 229 |
| abstract_inverted_index.presence | 45, 187 |
| abstract_inverted_index.provides | 314 |
| abstract_inverted_index.responds | 27 |
| abstract_inverted_index.response | 299 |
| abstract_inverted_index.specific | 34 |
| abstract_inverted_index.studying | 99 |
| abstract_inverted_index.(CAZymes) | 84 |
| abstract_inverted_index.activity. | 19 |
| abstract_inverted_index.cellulose | 179 |
| abstract_inverted_index.different | 29, 109, 174 |
| abstract_inverted_index.digesting | 38 |
| abstract_inverted_index.ethanol), | 131 |
| abstract_inverted_index.exhibited | 226 |
| abstract_inverted_index.expressed | 184, 221 |
| abstract_inverted_index.indicated | 43 |
| abstract_inverted_index.polymeric | 302 |
| abstract_inverted_index.potential | 127 |
| abstract_inverted_index.response, | 268 |
| abstract_inverted_index.secreting | 33 |
| abstract_inverted_index.secretion | 265 |
| abstract_inverted_index.secretome | 23 |
| abstract_inverted_index.substrate | 128 |
| abstract_inverted_index.suggested | 24 |
| abstract_inverted_index.(control). | 134 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.annotated. | 290 |
| abstract_inverted_index.expression | 52, 68, 101, 166, 228, 292 |
| abstract_inverted_index.identified | 11, 147 |
| abstract_inverted_index.laboratory | 14 |
| abstract_inverted_index.phenomenon | 42 |
| abstract_inverted_index.production | 326 |
| abstract_inverted_index.regulating | 66, 324 |
| abstract_inverted_index.regulation | 92 |
| abstract_inverted_index.regulatory | 48 |
| abstract_inverted_index.repertoire | 79 |
| abstract_inverted_index.sequenced, | 142, 279 |
| abstract_inverted_index.substrates | 31, 176 |
| abstract_inverted_index.(cellulosic | 112 |
| abstract_inverted_index.Conclusions | 271 |
| abstract_inverted_index.Penicillium | 2 |
| abstract_inverted_index.filamentous | 7 |
| abstract_inverted_index.funiculosum | 3, 138, 275 |
| abstract_inverted_index.hydrolyzing | 55, 180, 329 |
| abstract_inverted_index.identified. | 270, 310 |
| abstract_inverted_index.pre-treated | 123, 191 |
| abstract_inverted_index.substrate), | 113, 118 |
| abstract_inverted_index.substrates. | 40, 235 |
| abstract_inverted_index.Carbohydrate | 81 |
| abstract_inverted_index.cellulolytic | 18 |
| abstract_inverted_index.development, | 263 |
| abstract_inverted_index.functionally | 244 |
| abstract_inverted_index.characterized | 245 |
| abstract_inverted_index.comprehensive | 316 |
| abstract_inverted_index.heterogeneous | 207 |
| abstract_inverted_index.transcription | 58, 319 |
| abstract_inverted_index.hemicellulosic | 117 |
| abstract_inverted_index.hemicellulases, | 213 |
| abstract_inverted_index.lignocellulosic | 130, 307 |
| abstract_inverted_index.substrates—Avicel | 111 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 97 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/6 |
| sustainable_development_goals[0].score | 0.550000011920929 |
| sustainable_development_goals[0].display_name | Clean water and sanitation |
| citation_normalized_percentile.value | 0.80496627 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |