Systemic and Intravitreal Delivery of Dendrimers to Activated Microglia/Macrophage in Ischemia/Reperfusion Mouse Retina Article Swipe
Siva P. Kambhampati
,
Alexander J Clunies-Ross
,
Imran Ahmed Bhutto
,
Manoj K. Mishra
,
Malia M. Edwards
,
D. Scott McLeod
,
Rangaramanujam M. Kannan
,
Gerard A. Lutty
·
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1167/iovs.14-16250
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1167/iovs.14-16250
Intravitreal and systemic dendrimers target activated microglia and show qualitatively similar retinal biodistribution when administered by either route. Results provide proof-of-concept insights for developing dendrimer drug formulations as treatment options for retinal diseases associated with microglia or macrophage activation such as age-related macular degeneration, diabetic retinopathy, and retinal degenerations.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1167/iovs.14-16250
- https://iovs.arvojournals.org/arvo/content_public/journal/iovs/934219/i1552-5783-56-8-4413.pdf
- OA Status
- bronze
- Cited By
- 91
- References
- 41
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W1552284276
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W1552284276Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1167/iovs.14-16250Digital Object Identifier
- Title
-
Systemic and Intravitreal Delivery of Dendrimers to Activated Microglia/Macrophage in Ischemia/Reperfusion Mouse RetinaWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2015Year of publication
- Publication date
-
2015-07-15Full publication date if available
- Authors
-
Siva P. Kambhampati, Alexander J Clunies-Ross, Imran Ahmed Bhutto, Manoj K. Mishra, Malia M. Edwards, D. Scott McLeod, Rangaramanujam M. Kannan, Gerard A. LuttyList of authors in order
- Landing page
-
https://doi.org/10.1167/iovs.14-16250Publisher landing page
- PDF URL
-
https://iovs.arvojournals.org/arvo/content_public/journal/iovs/934219/i1552-5783-56-8-4413.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://iovs.arvojournals.org/arvo/content_public/journal/iovs/934219/i1552-5783-56-8-4413.pdfDirect OA link when available
- Concepts
-
Microglia, Retina, Macrophage, Ischemia, Dendrimer, Medicine, Chemistry, Inflammation, Immunology, Neuroscience, Biology, Internal medicine, In vitro, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
91Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 10, 2024: 6, 2023: 13, 2022: 7, 2021: 10Per-year citation counts (last 5 years)
- References (count)
-
41Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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