T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients Article Swipe
Flavio Palmieri
,
Julia Ramírez
,
Pablo Laguna
,
Pedro Gomis
,
Dina Ferreira
,
José Esteban Ruiz
,
Beatriz Bergasa
,
Alba Martín-Yebra
,
Syed Hassaan Ahmed Bukhari
,
Esther Pueyo
,
Juan Pablo Martínez
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.23919/cinc49843.2019.9005904
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.23919/cinc49843.2019.9005904
End-stage renal disease (ESRD) patients undergoing hemodialysis (HD) are at high risk of arrhythmias and sudden cardiac death as a result of blood potassium concentration ([K+ ]) changes. The aim of this study is to investigate if dw, a time-warping-based electrocardiogram (ECG) biomarker of T-wave morphology changes, reflects [K+] evolution in HD patients, facilitating noninvasive [K+] monitoring and avoiding in-hospital blood tests analysis. 48-hour ECGs and a set of hourly-collected blood samples from 12 ESRD patients were acquired and analyzed. dw was calculated between a reference T-wave, measured at the end of the HD session, and the T-waves corresponding to each hour along the whole HD session, when [K+] was measured from blood samples. The values of dw correlated with the relative variations in [K+] with respect to the reference value (end of HD, ¿[K+ ]), with a median (interquartile) correlation coefficient of 0.90 (0.30), evidencing a strong relation between them. Our findings support the use of dw as a surrogate of ¿[K+], suggesting a potential use of dw for non-invasive hyperkalemia monitoring both in hospital and ambulatory settings.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- http://zaguan.unizar.es/record/98287
- OA Status
- green
- Cited By
- 6
- References
- 11
- Related Works
- 20
- OpenAlex ID
- https://openalex.org/W2999012586
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2999012586Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.23919/cinc49843.2019.9005904Digital Object Identifier
- Title
-
T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis PatientsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2019Year of publication
- Publication date
-
2019-12-30Full publication date if available
- Authors
-
Flavio Palmieri, Julia Ramírez, Pablo Laguna, Pedro Gomis, Dina Ferreira, José Esteban Ruiz, Beatriz Bergasa, Alba Martín-Yebra, Syed Hassaan Ahmed Bukhari, Esther Pueyo, Juan Pablo MartínezList of authors in order
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https://zaguan.unizar.es/record/98287Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
- OA URL
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https://zaguan.unizar.es/record/98287Direct OA link when available
- Concepts
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Hemodialysis, Cardiology, Medicine, Internal medicine, Interquartile range, Hyperkalemia, Ambulatory, Biomarker, Chemistry, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
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2022: 1, 2021: 3, 2020: 2Per-year citation counts (last 5 years)
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11Number of works referenced by this work
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20Other works algorithmically related by OpenAlex
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