Tackling gender in progressive supranuclear palsy: Male patients present more apathy Article Swipe
Lan Ye
,
Stephan Greten
,
Ida Jensen
,
Florian Wegner
,
Lea Krey
,
Matthias Höllerhage
,
Monika Pötter‐Nerger
,
Molly Zeitzschel
,
Keno Hagena
,
Jan Kassubek
,
Patrick Süß
,
Jürgen Winkler
,
Daniela Berg
,
Steffen Paschen
,
Lars Tönges
,
Doreen Gruber
,
Florin Gandor
,
Wolfgang H. Jost
,
Andrea A. Kühn
,
Inga Claus
,
Tobias Warnecke
,
David J. Pedrosa
,
Carsten Eggers
,
Claudia Trenkwalder
,
Joseph Claßen
,
Johannes Schwarz
,
Alfons Schnitzler
,
Günter U. Höglinger
,
Martin Klietz
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1177/1877718x251343094
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1177/1877718x251343094
Gender differences in progressive supranuclear palsy (PSP) may become relevant for clinical trials, treatment decisions and patient counseling. To study gender associated differences we conducted a retrospective data analysis of 191 male and 157 female PSP patients from a large multicenter observational cohort in Germany. While no differences in motor skills, disease severity, daily living abilities, global cognitive status and depressive symptoms were observed between genders, male patients showed significantly higher apathy scores, a finding also noted in other neurological diseases. In this study, apart from male patients exhibiting higher levels of apathy, no significant disease-specific gender differences were observed in PSP patients.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1177/1877718x251343094
- OA Status
- diamond
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411020690
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4411020690Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1177/1877718x251343094Digital Object Identifier
- Title
-
Tackling gender in progressive supranuclear palsy: Male patients present more apathyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-06-04Full publication date if available
- Authors
-
Lan Ye, Stephan Greten, Ida Jensen, Florian Wegner, Lea Krey, Matthias Höllerhage, Monika Pötter‐Nerger, Molly Zeitzschel, Keno Hagena, Jan Kassubek, Patrick Süß, Jürgen Winkler, Daniela Berg, Steffen Paschen, Lars Tönges, Doreen Gruber, Florin Gandor, Wolfgang H. Jost, Andrea A. Kühn, Inga Claus, Tobias Warnecke, David J. Pedrosa, Carsten Eggers, Claudia Trenkwalder, Joseph Claßen, Johannes Schwarz, Alfons Schnitzler, Günter U. Höglinger, Martin KlietzList of authors in order
- Landing page
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https://doi.org/10.1177/1877718x251343094Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1177/1877718x251343094Direct OA link when available
- Concepts
-
Apathy, Progressive supranuclear palsy, Parkinson's disease, Disease, Observational study, Medicine, Retrospective cohort study, Psychology, Psychiatry, Pediatrics, Physical therapy, Clinical psychology, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
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15Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.While | 45 |
| abstract_inverted_index.apart | 84 |
| abstract_inverted_index.daily | 53 |
| abstract_inverted_index.large | 39 |
| abstract_inverted_index.motor | 49 |
| abstract_inverted_index.noted | 76 |
| abstract_inverted_index.other | 78 |
| abstract_inverted_index.palsy | 5 |
| abstract_inverted_index.study | 19 |
| abstract_inverted_index.Gender | 0 |
| abstract_inverted_index.apathy | 71 |
| abstract_inverted_index.become | 8 |
| abstract_inverted_index.cohort | 42 |
| abstract_inverted_index.female | 34 |
| abstract_inverted_index.gender | 20, 96 |
| abstract_inverted_index.global | 56 |
| abstract_inverted_index.higher | 70, 89 |
| abstract_inverted_index.levels | 90 |
| abstract_inverted_index.living | 54 |
| abstract_inverted_index.showed | 68 |
| abstract_inverted_index.status | 58 |
| abstract_inverted_index.study, | 83 |
| abstract_inverted_index.apathy, | 92 |
| abstract_inverted_index.between | 64 |
| abstract_inverted_index.disease | 51 |
| abstract_inverted_index.finding | 74 |
| abstract_inverted_index.patient | 16 |
| abstract_inverted_index.scores, | 72 |
| abstract_inverted_index.skills, | 50 |
| abstract_inverted_index.trials, | 12 |
| abstract_inverted_index.Germany. | 44 |
| abstract_inverted_index.analysis | 28 |
| abstract_inverted_index.clinical | 11 |
| abstract_inverted_index.genders, | 65 |
| abstract_inverted_index.observed | 63, 99 |
| abstract_inverted_index.patients | 36, 67, 87 |
| abstract_inverted_index.relevant | 9 |
| abstract_inverted_index.symptoms | 61 |
| abstract_inverted_index.cognitive | 57 |
| abstract_inverted_index.conducted | 24 |
| abstract_inverted_index.decisions | 14 |
| abstract_inverted_index.diseases. | 80 |
| abstract_inverted_index.patients. | 102 |
| abstract_inverted_index.severity, | 52 |
| abstract_inverted_index.treatment | 13 |
| abstract_inverted_index.abilities, | 55 |
| abstract_inverted_index.associated | 21 |
| abstract_inverted_index.depressive | 60 |
| abstract_inverted_index.exhibiting | 88 |
| abstract_inverted_index.counseling. | 17 |
| abstract_inverted_index.differences | 1, 22, 47, 97 |
| abstract_inverted_index.multicenter | 40 |
| abstract_inverted_index.progressive | 3 |
| abstract_inverted_index.significant | 94 |
| abstract_inverted_index.neurological | 79 |
| abstract_inverted_index.supranuclear | 4 |
| abstract_inverted_index.observational | 41 |
| abstract_inverted_index.retrospective | 26 |
| abstract_inverted_index.significantly | 69 |
| abstract_inverted_index.disease-specific | 95 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 29 |
| citation_normalized_percentile.value | 0.31368904 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |