Technique and impact on first pass effect primary results of the ASSIST global registry Article Swipe
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· 2024
· Open Access
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· DOI: https://doi.org/10.1136/jnis-2023-021126
Background Patients treated with mechanical thrombectomy (MT) for acute ischemic strokes from large vessel occlusion (LVO) have better outcomes with effective reperfusion. However, it is unknown which technique leads to better technical and clinical success. We aimed to determine which technique yields the most effective first pass reperfusion during MT. Methods In a prospective, multicenter global registry we enrolled patients treated with operator preferred MT technique at 71 hospitals from January 2019 to January 2022. Three techniques were assessed: SR Classic with stent retriever (SR) and balloon guide catheter (BGC); SR Combination which employed SR with contact aspiration with or without BGC; and direct aspiration (DA) with or without BGC. The primary outcome was achieving an expanded Thrombolysis In Cerebral Infarction (eTICI) score of 2c or 3 on the first pass, with the primary technique as adjudicated by core lab. The primary clinical outcome measure was a 90-day modified Rankin Scale (mRS) score of 0–2. Results A total of 1492 patients were enrolled. Patients treated with SR Classic or SR Combination were more likely to achieve first pass eTICI 2c or 3 reperfusion (P=0.01). There was no significant difference in mRS 0–2 (P=0.46) or safety endpoints. Conclusions The use of SR Classic or SR Combination was more likely to achieve first pass eTICI 2c or 3 reperfusion. There were no significant differences in clinical outcomes and safety endpoints.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/jnis-2023-021126
- https://jnis.bmj.com/content/neurintsurg/early/2024/01/09/jnis-2023-021126.full.pdf
- OA Status
- hybrid
- Cited By
- 24
- References
- 21
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4390698316
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4390698316Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/jnis-2023-021126Digital Object Identifier
- Title
-
Technique and impact on first pass effect primary results of the ASSIST global registryWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-01-09Full publication date if available
- Authors
-
Rishi Gupta, Salvador Miralbés, Angel Calleja Bonilla, Bharath Naravetla, Aniel Majjhoo, Mahmoud Rayes, Alejandro M Spiotta, Christian Loehr, Andreea Cioltan, Dominik F. Vollherbst, Mario Martínez‐Galdámez, Jorge Galván-Fernandez, Ahmad Khaldi, Ryan McTaggart, Mahesh Jayaraman, Luc Defreyne, Elisabeth Dhondt, Pedro Vega, Eduardo Murías, Eugene Lin, Varun Chaubal, Lori Lyn Price, David S. Liebeskind, Markus MöhlenbruchList of authors in order
- Landing page
-
https://doi.org/10.1136/jnis-2023-021126Publisher landing page
- PDF URL
-
https://jnis.bmj.com/content/neurintsurg/early/2024/01/09/jnis-2023-021126.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://jnis.bmj.com/content/neurintsurg/early/2024/01/09/jnis-2023-021126.full.pdfDirect OA link when available
- Concepts
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Medicine, First pass, Modified Rankin Scale, Thrombolysis, Occlusion, Clinical endpoint, Stroke (engine), Surgery, Internal medicine, Clinical trial, Ischemic stroke, Myocardial infarction, Ischemia, Mechanical engineering, Mathematics, Arithmetic, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
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24Total citation count in OpenAlex
- Citations by year (recent)
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2025: 14, 2024: 10Per-year citation counts (last 5 years)
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21Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| citation_normalized_percentile.value | 0.99089859 |
| citation_normalized_percentile.is_in_top_1_percent | True |
| citation_normalized_percentile.is_in_top_10_percent | True |