The Acid-Base Concept in Modern Supramolecular Chemistry Article Swipe
Matteo Savastano
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.26434/chemrxiv-2025-fdpm7
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.26434/chemrxiv-2025-fdpm7
Acid-Base theories/definitions were elaborated far before the onset of Supramolecular Chemistry. While acid-base official definitions have long remained untouched, in the last decade Supramolecular Chemistry provided many new additions to the IUPAC chemical vocabulary, e.g. halogen-, chalcogen, pnictogen-bond. The discussion moves from two distinct-yet-connected premises. First, the scope of supramolecular chemistry is addressed, and it is showed how existing official acid-base frameworks, essentially subtending to all donor-acceptor interactions - non-covalent ones included - are restrictive with respect to the general consensus and understanding of supramolecular interactions. Second, attention is brought to some underappreciated elements of novelty in the halogen- and post-halogen-bond IUPAC definitions, which, again, are not mirrored in current acid-base definitions. For these reasons, a quest is herein undertaken for an acid-base framework fully apt for supramolecular chemistry. This requires: first, reconsideration of both classical acid-base theories, including non-canonical ones (Lewis, Bronsted-Lowry, Arrhenius, Lux-Flood, SST, Usanovich, ionotropic definitions, etc…); second, of modern notable post-Lewis restatements (Mulliken, Jensen, Huheey, Drago, etc…). Discussion also addresses opportunities and reasons for these statements never to have reached IUPAC formalization. In such literature inspection, briefly addressing some History of Chemistry and Philosophy of Science topics, insights and key elements are collected which could assist in the formalization of an acid-base framework geared towards supramolecular chemistry. Brief discussion of the desirability and potential benefits of such an operation are discussed in a persistent dialogue among old ideas and modern supramolecular advancements. The ultimate goal of this work is to reconnect the acid-base historical discourse with its supramolecular modern declination, advocating for a holistic and inclusive view that, hopefully, could be one day officially formalized.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.26434/chemrxiv-2025-fdpm7
- https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/68b6b3e9a94eede1541392b3/original/the-acid-base-concept-in-modern-supramolecular-chemistry.pdf
- OA Status
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All OpenAlex metadata
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https://doi.org/10.26434/chemrxiv-2025-fdpm7Digital Object Identifier
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The Acid-Base Concept in Modern Supramolecular ChemistryWork title
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articleOpenAlex work type
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-09-05Full publication date if available
- Authors
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Matteo SavastanoList of authors in order
- Landing page
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https://doi.org/10.26434/chemrxiv-2025-fdpm7Publisher landing page
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https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/68b6b3e9a94eede1541392b3/original/the-acid-base-concept-in-modern-supramolecular-chemistry.pdfDirect link to full text PDF
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goldOpen access status per OpenAlex
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https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/68b6b3e9a94eede1541392b3/original/the-acid-base-concept-in-modern-supramolecular-chemistry.pdfDirect OA link when available
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Supramolecular chemistry, Base (topology), Chemistry, Computer science, Organic chemistry, Mathematics, Molecule, Mathematical analysisTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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