The Battle of the Pneumonia Predictors: A Comprehensive Meta-Analysis Comparing the Pneumonia Severity Index (PSI) and the CURB-65 Score in Predicting Mortality and the Need for ICU Support Article Swipe
Hany A Zaki
,
Baha Hamdi Alkahlout
,
Eman Shaban
,
Eslam Hussein Mohamed
,
Kaleem Basharat
,
Wael Abdelrehem Elnabawy Elsayed
,
Aftab Azad
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.7759/cureus.42672
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.7759/cureus.42672
The CURB-65 (confusion, uremia, respiratory rate, blood pressure, age ≥ 65 years) score and the pneumonia severity index (PSI) are widely used and recommended in predicting 30-day mortality and the need for intensive care support in community-acquired pneumonia. This study aims to compare the performance of these two severity scores in both mortality prediction and the need for intensive care support. A systematic review and meta-analysis was carried out, following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) 2020 guidelines, and PubMed, Scopus, ScienceDirect, and Google Scholar were searched for articles published from 2012 to 2022. The reference lists of the included studies were also searched to retrieve possible additional studies. Twenty-five studies reporting prognostic information for CURB 65 and PSI were identified. ReviewManager (RevMan) 5.4.1 was used to produce risk ratios, and a random effects model was used to pool them. Both PSI and CURB-65 showed a high strength in identifying high-risk patients. However, CURB-65 was slightly better in early mortality prediction and had more sensitivity (96.7%) and specificity (89.3%) in predicting admission to intensive care support. Thus, CURB-65 seems to be the preferred tool in predicting mortality and the need for admission into intensive care support.
Related Topics
Concepts
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.7759/cureus.42672
- https://assets.cureus.com/uploads/review_article/pdf/170716/20230730-19060-1rs83hm.pdf
- OA Status
- diamond
- Cited By
- 36
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4385386955
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4385386955Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.7759/cureus.42672Digital Object Identifier
- Title
-
The Battle of the Pneumonia Predictors: A Comprehensive Meta-Analysis Comparing the Pneumonia Severity Index (PSI) and the CURB-65 Score in Predicting Mortality and the Need for ICU SupportWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-07-29Full publication date if available
- Authors
-
Hany A Zaki, Baha Hamdi Alkahlout, Eman Shaban, Eslam Hussein Mohamed, Kaleem Basharat, Wael Abdelrehem Elnabawy Elsayed, Aftab AzadList of authors in order
- Landing page
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https://doi.org/10.7759/cureus.42672Publisher landing page
- PDF URL
-
https://assets.cureus.com/uploads/review_article/pdf/170716/20230730-19060-1rs83hm.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://assets.cureus.com/uploads/review_article/pdf/170716/20230730-19060-1rs83hm.pdfDirect OA link when available
- Concepts
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Medicine, Pneumonia severity index, Meta-analysis, Pneumonia, Intensive care, Intensive care medicine, MEDLINE, Systematic review, Emergency medicine, Community-acquired pneumonia, Internal medicine, Political science, LawTop concepts (fields/topics) attached by OpenAlex
- Cited by
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36Total citation count in OpenAlex
- Citations by year (recent)
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2025: 18, 2024: 14, 2023: 4Per-year citation counts (last 5 years)
- References (count)
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46Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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