The CircumVent Project: a CPAP/O2 helmet solution for non-invasive ventilation using an implementation research framework Article Swipe
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· 2021
· Open Access
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· DOI: https://doi.org/10.1186/s43058-021-00193-y
Background Acute respiratory failure, a major cause of death in COVID-19, is managed with high-flow oxygen therapy via invasive mechanical ventilation. In resource-limited settings like Nigeria, the shortage of ventilators and oxygen supply makes this option challenging. Evidence-based non-invasive alternatives to mechanical ventilation such as the use of continuous positive airway pressure (CPAP) devices exist, but there have been concerns that non-invasive ventilation may expose healthcare workers to infection from aerosolized dispersion of SARS-CoV-2. We propose to evaluate the feasibility, adaptability and acceptability of a CPAP/O 2 helmet solution for non-invasive ventilation among patients with COVID-19 and health workers in eight COVID-19 treatment and isolation centers in Nigeria. Methods The study will occur in 4 stages: (1) convene a Steering Committee of key stakeholders and recruit implementation sites; (2) use the integrated Promoting Action on Research Implementation in Health Services (i-PARiHS) framework to guide a needs assessment of treatment centers’ capacity to use high-flow oxygen therapy to treat COVID-19 patients and utilize the findings to develop an implementation strategy for the use of a CPAP/O 2 helmet solution; (3) build infrastructure to support training and data monitoring processes and to develop implementation protocols to evaluate the adaptability of the strategy for the use of the CPAP/O 2 helmet; and (4) train health workers, distribute a CPAP/O 2 helmet solution for non-invasive ventilation, pilot test the implementation strategy, and assess feasibility of its use and acceptability that includes monitoring altered risk of SARS-CoV-2 infection among healthcare workers. Discussion The CPAP/O 2 helmet solution for non-invasive ventilation in Nigeria can serve as a scalable model for resource-poor countries, and beyond the COVID-19 pandemic, has the potential to be deployed for the treatment of pneumonia and other respiratory diseases. Trial registration NCT04929691. Registered June 18, 2021—retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04929691
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s43058-021-00193-y
- https://implementationsciencecomms.biomedcentral.com/track/pdf/10.1186/s43058-021-00193-y
- OA Status
- gold
- Cited By
- 4
- References
- 24
- Related Works
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- OpenAlex ID
- https://openalex.org/W3195238872
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3195238872Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s43058-021-00193-yDigital Object Identifier
- Title
-
The CircumVent Project: a CPAP/O2 helmet solution for non-invasive ventilation using an implementation research frameworkWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-08-26Full publication date if available
- Authors
-
Aimalohi A. Ahonkhai, Adesola Z. Musa, André A. Fenton, Muktar H. Aliyu, Igho Ofotokun, Alex Hornstein, Baba Maiyaki Musa, Nnamdi Nwosu, Ifeoma Ulasi, Samuel Ajayi, Catherine O. Falade, Adedamola A. Dada, Aliyu Abdu, Mogaji Sunday, Adenike Odewabi, Muyiwa Rotimi, Onome Ogueh, Alan Steinbach, Gbenga Ogedegbe, Babatunde Lawal Salako, Oliver EzechiList of authors in order
- Landing page
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https://doi.org/10.1186/s43058-021-00193-yPublisher landing page
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https://implementationsciencecomms.biomedcentral.com/track/pdf/10.1186/s43058-021-00193-yDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://implementationsciencecomms.biomedcentral.com/track/pdf/10.1186/s43058-021-00193-yDirect OA link when available
- Concepts
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Continuous positive airway pressure, Adaptability, Personal protective equipment, Ventilation (architecture), Medicine, Health care, Mechanical ventilation, Intensive care medicine, Medical emergency, Coronavirus disease 2019 (COVID-19), Engineering, Economics, Internal medicine, Pathology, Infectious disease (medical specialty), Psychiatry, Mechanical engineering, Biology, Disease, Obstructive sleep apnea, Ecology, Economic growthTop concepts (fields/topics) attached by OpenAlex
- Cited by
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4Total citation count in OpenAlex
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2023: 1, 2022: 3Per-year citation counts (last 5 years)
- References (count)
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24Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| referenced_works | https://openalex.org/W3026699536, https://openalex.org/W2381033283, https://openalex.org/W2068178744, https://openalex.org/W2756170300, https://openalex.org/W2149263201, https://openalex.org/W2507125133, https://openalex.org/W2391719988, https://openalex.org/W2306592406, https://openalex.org/W2567648295, https://openalex.org/W1963650240, https://openalex.org/W2914546156, https://openalex.org/W2072149071, https://openalex.org/W3091789929, https://openalex.org/W2750615195, https://openalex.org/W3023639742, https://openalex.org/W2775411160, https://openalex.org/W6776783366, https://openalex.org/W2890887447, https://openalex.org/W2619286966, https://openalex.org/W1990743521, https://openalex.org/W2977697366, https://openalex.org/W2612597266, https://openalex.org/W3024202587, https://openalex.org/W2782857592 |
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