The effect of enhanced recovery after minimally invasive esophagectomy: a randomized controlled trial Article Swipe
YOU?
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· 2022
· Open Access
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· DOI: https://doi.org/10.1007/s00464-022-09385-6
Background The purpose of this randomized controlled trial was to determine if enhanced recovery after surgery (ERAS) would improve outcomes for three-stage minimally invasive esophagectomy (MIE). Methods Patients with esophageal cancer undergoing MIE between March 2016 and August 2018 were consecutively enrolled, and were randomly divided into 2 groups: ERAS+group that received a guideline-based ERAS protocol, and ERAS- group that received standard care. The primary endpoint was morbidity after MIE. The secondary endpoints were the length of stay (LOS) and time to ambulation after the surgery. The perioperative results including the Surgical Apgar Score (SAS) and Visualized Analgesia Score (VAS) were also collected and compared. Results A total of 60 patients in the ERAS+ group and 58 patients in the ERAS- group were included. Postoperatively, lower morbidity and pulmonary complication rate were recorded in the ERAS+ group (33.3% vs. 51.7%; p = 0.04, 16.7% vs. 32.8%; p = 0.04), while the incidence of anastomotic leakage remained comparable (11.7% vs. 15.5%; p = 0.54). There was an earlier ambulation (3 [2–3] days vs. 3 [3–4] days, p = 0.001), but comparable LOS (10 [9–11.25] days vs. 10 [9–13] days; p = 0.165) recorded in ERAS+ group. The ERAS protocol led to close scores in both SAS (7.80 ± 1.03 vs. 8.07 ± 0.89, p = 0.21) and VAS (1.74 ± 0.85 vs. 1.78 ± 1.06, p = 0.84). Conclusions Implementation of an ERAS protocol for patients undergoing MIE resulted in earlier ambulation and lower pulmonary complications, without a change in anastomotic leakage or length of hospital stay. Further studies on minimizing leakage should be addressed in ERAS for MIE.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1007/s00464-022-09385-6
- https://link.springer.com/content/pdf/10.1007/s00464-022-09385-6.pdf
- OA Status
- hybrid
- Cited By
- 22
- References
- 43
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4283756317
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4283756317Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1007/s00464-022-09385-6Digital Object Identifier
- Title
-
The effect of enhanced recovery after minimally invasive esophagectomy: a randomized controlled trialWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-06-30Full publication date if available
- Authors
-
Yaxing Shen, Xiaosang Chen, Junyi Hou, Youwen Chen, Yong Fang, Zhanggang Xue, Xavier Benoît D’Journo, Robert J. Cerfolio, Hiran C. Fernando, Alfonso Fiorelli, Alessandro Brunelli, Jing Cang, Lijie Tan, Hao WangList of authors in order
- Landing page
-
https://doi.org/10.1007/s00464-022-09385-6Publisher landing page
- PDF URL
-
https://link.springer.com/content/pdf/10.1007/s00464-022-09385-6.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://link.springer.com/content/pdf/10.1007/s00464-022-09385-6.pdfDirect OA link when available
- Concepts
-
Medicine, Randomized controlled trial, Perioperative, Esophagectomy, Surgery, Clinical endpoint, Abdominal surgery, Incidence (geometry), Esophageal cancer, Internal medicine, Cancer, Physics, OpticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
22Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 11, 2024: 7, 2023: 4Per-year citation counts (last 5 years)
- References (count)
-
43Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| publication_date | 2022-06-30 |
| publication_year | 2022 |
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