The effects of sequencing strategies on Metagenomic pathogen detection using bronchoalveolar lavage fluid samples Article Swipe

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Pathogen DNA sequencing Metagenomics Computational biology Biology Precision and recall Computer science Artificial intelligence Genetics DNA Gene

Ziyang Li , Zhe Guo , Weimin Wu , Li Tan , Qichen Long , Han Xia , Min Hu ·

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YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1016/j.heliyon.2024.e33429 · OA: W4399920513

Increasing dataset sizes and read lengths can enhance the performance of mNGS in pathogen detection but increase the economic and time costs of sequencing and data analysis. Currently, the 20 M reads in SE75 mode may be the best sequencing option.

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