The european registry for patients with mechanical circulatory support (EUROMACS): fourth paediatric EUROMACS (Paedi-EUROMACS) report Article Swipe
Sofie Rohde
,
Joeri Van Puyvelde
,
Kevin M. Veen
,
Martin Schweiger
,
Daniel Biermann
,
Antonio Amodeo
,
Thomas Martens
,
Kevin Damman
,
Can Gollmann‐Tepeköylü
,
Michal Hulman
,
Attilio Iacovoni
,
Ulrike S Krämer
,
Antonio Loforte
,
Carlo Pace Napoleone
,
Petr Němec
,
Ivan Netuka
,
Mustafa Özbaran
,
Luz Polo
,
Yuriy Pya
,
Faiz Ramjankhan
,
Eugen Sandica
,
Joanna Śliwka
,
Brigitte Stiller
,
Alexander Kadner
,
Alessio Franceschini
,
Timothy Thiruchelvam
,
Daniel Zimpfer
,
Felix Berger
,
Ben Davies
,
Alexey Dashkevich
,
Christoffer Stark
,
Bart Meyns
,
Theo M M H de By
,
Olivier Miera
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/ejcts/ezae276
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/ejcts/ezae276
OBJECTIVES The use of ventricular assist devices in children is increasing. However, absolute numbers in individual centers and countries remain small. Collaborative efforts such as the Paedi-EUROMACS are therefore essential in order to combine international experience with paediatric ventricular assist devices. In this paper, the results from the fourth Paedi-EUROMACS report are presented. METHODS All paediatric (<19 years) patients supported by a ventricular assist device from the EUROMACS database were included. Patients are stratified into a congenital heart disease group and a group with a non-congenital aetiology. Endpoints included mortality, transplantation and recovery. Cox proportional hazard models were used to explore associated factors for mortality, cerebrovascular accident, and pump thrombosis. RESULTS 590 primary implantations were included. The congenital group was significantly younger (2.5 versus 8.0 years respectively, p < 0.001) and were more commonly supported by a pulsatile flow device (73.5% vs 59.9%, p < 0.001). Mortality was significantly higher in the congenital group (30.8 vs 20.4%; p = 0.009) than in the non-congenital group. However, in multivariable analyses, congenital heart disease was not significantly associated with mortality (HR 1.285, CI 0.8111–2.036, p = 0.740). Pump thrombosis was the most frequently reported adverse event (377 events in 132 patients; 0.925 events per patient-year) and was significantly associated with BSA (HR 0.524 CI 0.333–0.823, p = 0.005), congenital heart disease (HR 1.641 CI 1.054–2.555, p = 0.028) and pulsatile flow support (HR 2.345 CI 1.406–3.910, p = 0.001) in multivariable analyses. CONCLUSIONS This fourth Paedi-EUROMACS report highlights the increasing use of paediatric ventricular assist devices. The patient populations with congenital and non-congenital aetiology exhibit distinct characteristics and clinical outcomes.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/ejcts/ezae276
- OA Status
- green
- Cited By
- 3
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400863617
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4400863617Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/ejcts/ezae276Digital Object Identifier
- Title
-
The european registry for patients with mechanical circulatory support (EUROMACS): fourth paediatric EUROMACS (Paedi-EUROMACS) reportWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-07-19Full publication date if available
- Authors
-
Sofie Rohde, Joeri Van Puyvelde, Kevin M. Veen, Martin Schweiger, Daniel Biermann, Antonio Amodeo, Thomas Martens, Kevin Damman, Can Gollmann‐Tepeköylü, Michal Hulman, Attilio Iacovoni, Ulrike S Krämer, Antonio Loforte, Carlo Pace Napoleone, Petr Němec, Ivan Netuka, Mustafa Özbaran, Luz Polo, Yuriy Pya, Faiz Ramjankhan, Eugen Sandica, Joanna Śliwka, Brigitte Stiller, Alexander Kadner, Alessio Franceschini, Timothy Thiruchelvam, Daniel Zimpfer, Felix Berger, Ben Davies, Alexey Dashkevich, Christoffer Stark, Bart Meyns, Theo M M H de By, Olivier MieraList of authors in order
- Landing page
-
https://doi.org/10.1093/ejcts/ezae276Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://research.rug.nl/en/publications/9b4f7955-1e5c-4a78-a7ab-ff595eff965cDirect OA link when available
- Concepts
-
Medicine, Ventricular assist device, Hazard ratio, Heart disease, Internal medicine, Cardiology, Heart transplantation, Etiology, Heart failure, Proportional hazards model, Pulsatile flow, Pediatrics, Confidence intervalTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
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2025: 3Per-year citation counts (last 5 years)
- Related works (count)
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10Other works algorithmically related by OpenAlex
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