The Feasibility of the “Omega Kid” Study Protocol: A Double-Blind, Randomised, Placebo-Controlled Trial Investigating the Effect of Omega-3 Supplementation on Self-Regulation in Preschool-Aged Children Article Swipe
Lauren A. Roach
,
Mitchell K. Byrne
,
Steven J. Howard
,
Stuart J. Johnstone
,
Marijka Batterham
,
Ian Wright
,
Anthony D. Okely
,
Renate H. M. de Groot
,
I.S.M. van der Wurff
,
Alison L Jones
,
Barbara J. Meyer
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/nu13010213
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.3390/nu13010213
Self-regulation, the regulation of behaviour in early childhood, impacts children’s success at school and is a predictor of health, wealth, and criminal outcomes in adulthood. Self-regulation may be optimised by dietary supplementation of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs). The aim of the “Omega Kid” study is to investigate the feasibility of a protocol to investigate whether n-3 LCPUFA supplementation enhances self-regulation in preschool-aged children. The protocol assessed involved a double-blind, randomised, placebo-controlled trial of 12 weeks duration, with an intervention of 1.6 g of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) per day (0.3 g EPA and 1.3 g DHA) in a microencapsulated powder compared to placebo. Children (n = 78; 40 boys and 38 girls) aged 3–5 years old were recruited and randomly allocated to the treatment (n = 39) or placebo group (n = 39). The HS–Omega-3 Index® served as a manipulation check on the delivery of either active (n-3 LCPUFAs) or placebo powders. Fifty-eight children (76%) completed the intervention (28–30 per group). Compliance to the study protocol was high, with 92% of children providing a finger-prick blood sample at baseline and high reported-adherence to the study intervention (88%). Results indicate that the protocol is feasible and may be employed in an adequately powered clinical trial to test the hypothesis that n-3 LCPUFA supplementation will improve the self-regulation of preschool-aged children.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/nu13010213
- https://www.mdpi.com/2072-6643/13/1/213/pdf?version=1610543753
- OA Status
- gold
- Cited By
- 1
- References
- 45
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3120482729
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3120482729Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/nu13010213Digital Object Identifier
- Title
-
The Feasibility of the “Omega Kid” Study Protocol: A Double-Blind, Randomised, Placebo-Controlled Trial Investigating the Effect of Omega-3 Supplementation on Self-Regulation in Preschool-Aged ChildrenWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-01-13Full publication date if available
- Authors
-
Lauren A. Roach, Mitchell K. Byrne, Steven J. Howard, Stuart J. Johnstone, Marijka Batterham, Ian Wright, Anthony D. Okely, Renate H. M. de Groot, I.S.M. van der Wurff, Alison L Jones, Barbara J. MeyerList of authors in order
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https://doi.org/10.3390/nu13010213Publisher landing page
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https://www.mdpi.com/2072-6643/13/1/213/pdf?version=1610543753Direct link to full text PDF
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2072-6643/13/1/213/pdf?version=1610543753Direct OA link when available
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Placebo, Omega, Medicine, Randomized controlled trial, Double blind, Physical therapy, Psychology, Internal medicine, Alternative medicine, Physics, Pathology, Quantum mechanicsTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2021: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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