The ICGC ARGO data dictionary for standardizing global cancer clinical data Article Swipe
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· 2025
· Open Access
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· DOI: https://doi.org/10.1038/s41597-025-06068-4
The International Cancer Genome Consortium Accelerating Research in Genomic Oncology (ICGC ARGO) project is an international initiative to sequence germline and tumour genomes from 100,000 cancer patients across 13 countries and 22 tumour types. By integrating genomic data with comprehensive clinical information including treatment outcomes, lifestyle, environmental exposures and family history, ICGC ARGO aims to accelerate the application of genomic insights in cancer diagnosis, treatment and prevention. However, a major challenge is harmonizing clinical data from diverse tumour types worldwide. To address this, the ICGC ARGO Data Dictionary was developed to ensure consistent high-quality clinical data collection by defining a minimal set of clinical fields within an event-based data model to capture clinical relationships and support longitudinal data collection. Grounded in international standardized terminology, it is interoperable with other data standards such as Minimal Common Oncology Data Elements (mCODE). Its adoption by global initiatives such as the European-Canadian Cancer Network (EUCANCan) and the Marathon of Hope Cancer Centres Network (MOHCCN) underscores its broad impact on advancing precision oncology research.
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- article
- Language
- en
- Landing Page
- https://doi.org/10.1038/s41597-025-06068-4
- https://www.nature.com/articles/s41597-025-06068-4.pdf
- OA Status
- gold
- References
- 26
- OpenAlex ID
- https://openalex.org/W7106116732
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W7106116732Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1038/s41597-025-06068-4Digital Object Identifier
- Title
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The ICGC ARGO data dictionary for standardizing global cancer clinical dataWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
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2025-11-20Full publication date if available
- Authors
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Hardeep K. Nahal-Bose, Peter Lichter, Ursula Weber, Lincoln D Stein, Rosita Bajari, Linda Xiang, Edmund Su, Jon Eubank, Ciarán Schütte, Christina K. Yung, Melanie Courtot, Hardeep K. Nahal-Bose, Peter Lichter, Ursula Weber, Lincoln D Stein, Rosita Bajari, Linda Xiang, Edmund Su, Jon Eubank, Ciarán Schütte, Christina K. Yung, Melanie CourtotList of authors in order
- Landing page
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https://doi.org/10.1038/s41597-025-06068-4Publisher landing page
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https://www.nature.com/articles/s41597-025-06068-4.pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
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https://www.nature.com/articles/s41597-025-06068-4.pdfDirect OA link when available
- Concepts
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Interoperability, Cancer, Clinical Oncology, Data science, Argo, Precision oncology, Germline, Genome, Medicine, Genomics, Metadata, Computer science, Oncology, Data set, Computational biology, Medical physics, Set (abstract data type), Data collection, MEDLINE, Genomic information, Precision medicine, Clinical trial, Bioinformatics, Cancer treatment, Translational research, Internal medicine, DNA sequencing, Clinical research, Data mining, Family medicine, Information repositoryTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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26Number of works referenced by this work
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