The Impact of Routine Transvaginal Ultrasound Measurement of the Cervical Length on the Prediction of Preterm Birth: A Retrospective Study in a Tertiary Hospital Article Swipe
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· 2021
· Open Access
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· DOI: https://doi.org/10.1055/s-0041-1726053
Preterm birth (PTB) is a major obstetric problem associated with high rates of neonatal morbidity and mortality. The prevalence of PTB has not changed in the last decade; thus, the establishment of a screening test and effective treatment are warranted. Transvaginal ultrasound measurement of the cervical length (TUCL) has been proposed as an effective method to screen pregnant women at a higher risk of experiencing PTB. Objective To evaluate the applicability and usefulness of second-trimester TUCL to predict PTB in a cohort of Portuguese pregnant women. Methods Retrospective cross-sectional cohort study including all singleton pregnant women who performed their second-trimester ultrasound (between weeks 18 and 22 + 6 days) from January 2013 to October 2017 at Centro Hospitalar Universitário São João. Results Our cohort included 4,481 women. The prevalence of spontaneous PTB was of 4.0%, with 0.7% occurring before the 34th week of gestation. The mean TUCL was of 33.8 mm, and percentiles 3, 5 and 10 corresponded to TUCLs of 25.0 mm, 27.0 mm and 29.0 mm respectively. The multiple logistic regression analysis, including maternal age, previous PTB and cervical surgery showed a significant negative association between TUCL and PTB, with an odds ratio (OR) of 0.92 (95% confidence interval [95%CI]: 0.90–0.95; p < 0.001). The use of a TUCL of 20 mm is the best cut-off, when compared with the 25-mm cut-off, improving the prediction of risk. Conclusion The present study showed an inverse association between TUCL and PTB, and that the inclusion of other risk factors like maternal age, previous PTB and cervical surgery can improve the screening algorithm. Furthermore, it emphasizes that the TUCL cut-off that defines short cervix can differ according to the population.
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- article
- Language
- en
- Landing Page
- https://doi.org/10.1055/s-0041-1726053
- http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1726053.pdf
- OA Status
- diamond
- Cited By
- 2
- References
- 51
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3160124852
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3160124852Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1055/s-0041-1726053Digital Object Identifier
- Title
-
The Impact of Routine Transvaginal Ultrasound Measurement of the Cervical Length on the Prediction of Preterm Birth: A Retrospective Study in a Tertiary HospitalWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-04-01Full publication date if available
- Authors
-
Joana Patrícia Rodrigues Félix Peixoto de Almeida, Carla Bartosch, Alexandra MatiasList of authors in order
- Landing page
-
https://doi.org/10.1055/s-0041-1726053Publisher landing page
- PDF URL
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https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1726053.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1726053.pdfDirect OA link when available
- Concepts
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Medicine, Obstetrics, Retrospective cohort study, Odds ratio, Confidence interval, Logistic regression, Cohort, Percentile, Gestation, Cohort study, Gynecology, Pregnancy, Surgery, Internal medicine, Mathematics, Biology, Statistics, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
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2024: 2Per-year citation counts (last 5 years)
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51Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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