The Impact of Stool Consistency on Bowel Movement Satisfaction in Patients With IBS-C or CIC Treated With Linaclotide or Other Medications Article Swipe
Douglas C.A. Taylor
,
Jessica L. Abel
,
Jalpa A. Doshi
,
Carolyn Martin
,
Alyssa Goolsby Hunter
,
Breanna Essoi
,
Stephanie Korrer
,
David S. Reasner
,
Robyn T. Carson
,
William D. Chey
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1097/mcg.0000000000001245
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1097/mcg.0000000000001245
Goals: This study aimed to characterize the impact of stool consistency on patient-reported bowel movement (BM) satisfaction in patients with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation, with a focus on linaclotide. Background: As new medications for constipation become available, understanding patients’ perceptions of treatment effects may help clinicians manage patient expectations and inform clinical decision-making. Materials and Methods: Data were derived from the Chronic Constipation and IBS-C Treatment and Outcomes Real-world Research Platform (CONTOR) study from 2 patient-reported 7-day daily BM diaries to create a dataset of 2922 diaries representing 26,524 BMs for 1806 participants. Binary variables were created for: medication(s) used in the past 24 hours and categorization of BMs as loose or watery stools (LoWS), hard or lumpy stools (HoLS), or intermediate (neither LoWS nor HoLS). The relationship between stool consistency, medication use, and BM satisfaction was analyzed using logistic regression with SEs corrected for repeated observations. Results: BMs characterized as intermediate stools and LoWS were satisfactory more often (61.2% and 51.2%, respectively) than HoLS (19.4%). Participants who reported taking linaclotide rated a similar proportion of BMs as satisfactory when described as LoWS (65.6%) or intermediate (64.1%). Linaclotide use was associated with higher odds of BMs being reported as satisfactory compared with nonlinaclotide use (odds ratio: 1.23, P <0.05). Conclusions: Overall, CONTOR participants were more likely to report BMs classified as LoWS or intermediate as satisfactory, versus HoLS. Participants taking linaclotide were more likely to be satisfied, particularly those reporting LoWS, versus those not taking linaclotide.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1097/mcg.0000000000001245
- OA Status
- hybrid
- Cited By
- 5
- References
- 22
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2965283819
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2965283819Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1097/mcg.0000000000001245Digital Object Identifier
- Title
-
The Impact of Stool Consistency on Bowel Movement Satisfaction in Patients With IBS-C or CIC Treated With Linaclotide or Other MedicationsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-07-30Full publication date if available
- Authors
-
Douglas C.A. Taylor, Jessica L. Abel, Jalpa A. Doshi, Carolyn Martin, Alyssa Goolsby Hunter, Breanna Essoi, Stephanie Korrer, David S. Reasner, Robyn T. Carson, William D. CheyList of authors in order
- Landing page
-
https://doi.org/10.1097/mcg.0000000000001245Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1097/mcg.0000000000001245Direct OA link when available
- Concepts
-
Medicine, Irritable bowel syndrome, Constipation, Internal medicine, Defecation, Odds ratio, Gastroenterology, Logistic regression, Chronic constipation, Physical therapyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
5Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 2, 2021: 3Per-year citation counts (last 5 years)
- References (count)
-
22Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2965283819 |
|---|---|
| doi | https://doi.org/10.1097/mcg.0000000000001245 |
| ids.doi | https://doi.org/10.1097/mcg.0000000000001245 |
| ids.mag | 2965283819 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/31361710 |
| ids.openalex | https://openalex.org/W2965283819 |
| fwci | 0.62910535 |
| mesh[0].qualifier_ui | Q000188 |
| mesh[0].descriptor_ui | D003248 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | drug therapy |
| mesh[0].descriptor_name | Constipation |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D016208 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Databases, Factual |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D003672 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Defecation |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D005243 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Feces |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D005260 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Female |
| mesh[5].qualifier_ui | Q000008 |
| mesh[5].descriptor_ui | D000074268 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | administration & dosage |
| mesh[5].descriptor_name | Guanylyl Cyclase C Agonists |
| mesh[6].qualifier_ui | Q000627 |
| mesh[6].descriptor_ui | D000074268 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | therapeutic use |
| mesh[6].descriptor_name | Guanylyl Cyclase C Agonists |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D006801 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Humans |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D007345 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Insurance Claim Review |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D043183 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Irritable Bowel Syndrome |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D008297 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Male |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D008875 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Middle Aged |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D017060 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Patient Satisfaction |
| mesh[13].qualifier_ui | Q000008 |
| mesh[13].descriptor_ui | D010455 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | administration & dosage |
| mesh[13].descriptor_name | Peptides |
| mesh[14].qualifier_ui | Q000627 |
| mesh[14].descriptor_ui | D010455 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | therapeutic use |
| mesh[14].descriptor_name | Peptides |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D004364 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Pharmaceutical Preparations |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D011795 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Surveys and Questionnaires |
| mesh[17].qualifier_ui | Q000188 |
| mesh[17].descriptor_ui | D003248 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | drug therapy |
| mesh[17].descriptor_name | Constipation |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D016208 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Databases, Factual |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D003672 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Defecation |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D005243 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Feces |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D005260 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Female |
| mesh[22].qualifier_ui | Q000008 |
| mesh[22].descriptor_ui | D000074268 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | administration & dosage |
| mesh[22].descriptor_name | Guanylyl Cyclase C Agonists |
| mesh[23].qualifier_ui | Q000627 |
| mesh[23].descriptor_ui | D000074268 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | therapeutic use |
| mesh[23].descriptor_name | Guanylyl Cyclase C Agonists |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D006801 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Humans |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D007345 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Insurance Claim Review |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D043183 |
| mesh[26].is_major_topic | True |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Irritable Bowel Syndrome |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D008297 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Male |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D008875 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Middle Aged |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D017060 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Patient Satisfaction |
| mesh[30].qualifier_ui | Q000008 |
| mesh[30].descriptor_ui | D010455 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | administration & dosage |
| mesh[30].descriptor_name | Peptides |
| mesh[31].qualifier_ui | Q000627 |
| mesh[31].descriptor_ui | D010455 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | therapeutic use |
| mesh[31].descriptor_name | Peptides |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D004364 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Pharmaceutical Preparations |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D011795 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Surveys and Questionnaires |
| type | article |
| title | The Impact of Stool Consistency on Bowel Movement Satisfaction in Patients With IBS-C or CIC Treated With Linaclotide or Other Medications |
| biblio.issue | 10 |
| biblio.volume | 53 |
| biblio.last_page | 743 |
| biblio.first_page | 737 |
| topics[0].id | https://openalex.org/T10365 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2715 |
| topics[0].subfield.display_name | Gastroenterology |
| topics[0].display_name | Gastrointestinal motility and disorders |
| topics[1].id | https://openalex.org/T12237 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9824000000953674 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2746 |
| topics[1].subfield.display_name | Surgery |
| topics[1].display_name | Congenital gastrointestinal and neural anomalies |
| topics[2].id | https://openalex.org/T10671 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9790999889373779 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2715 |
| topics[2].subfield.display_name | Gastroenterology |
| topics[2].display_name | Gastroesophageal reflux and treatments |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9250272512435913 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C2778271842 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7869044542312622 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q838966 |
| concepts[1].display_name | Irritable bowel syndrome |
| concepts[2].id | https://openalex.org/C2781112942 |
| concepts[2].level | 2 |
| concepts[2].score | 0.7400041222572327 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q178436 |
| concepts[2].display_name | Constipation |
| concepts[3].id | https://openalex.org/C126322002 |
| concepts[3].level | 1 |
| concepts[3].score | 0.6599812507629395 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[3].display_name | Internal medicine |
| concepts[4].id | https://openalex.org/C108797546 |
| concepts[4].level | 2 |
| concepts[4].score | 0.543303906917572 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q204015 |
| concepts[4].display_name | Defecation |
| concepts[5].id | https://openalex.org/C156957248 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5258370637893677 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q1862216 |
| concepts[5].display_name | Odds ratio |
| concepts[6].id | https://openalex.org/C90924648 |
| concepts[6].level | 1 |
| concepts[6].score | 0.5219040513038635 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q120569 |
| concepts[6].display_name | Gastroenterology |
| concepts[7].id | https://openalex.org/C151956035 |
| concepts[7].level | 2 |
| concepts[7].score | 0.5009274482727051 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1132755 |
| concepts[7].display_name | Logistic regression |
| concepts[8].id | https://openalex.org/C3017955636 |
| concepts[8].level | 3 |
| concepts[8].score | 0.416654109954834 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q178436 |
| concepts[8].display_name | Chronic constipation |
| concepts[9].id | https://openalex.org/C1862650 |
| concepts[9].level | 1 |
| concepts[9].score | 0.337436318397522 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q186005 |
| concepts[9].display_name | Physical therapy |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.9250272512435913 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/irritable-bowel-syndrome |
| keywords[1].score | 0.7869044542312622 |
| keywords[1].display_name | Irritable bowel syndrome |
| keywords[2].id | https://openalex.org/keywords/constipation |
| keywords[2].score | 0.7400041222572327 |
| keywords[2].display_name | Constipation |
| keywords[3].id | https://openalex.org/keywords/internal-medicine |
| keywords[3].score | 0.6599812507629395 |
| keywords[3].display_name | Internal medicine |
| keywords[4].id | https://openalex.org/keywords/defecation |
| keywords[4].score | 0.543303906917572 |
| keywords[4].display_name | Defecation |
| keywords[5].id | https://openalex.org/keywords/odds-ratio |
| keywords[5].score | 0.5258370637893677 |
| keywords[5].display_name | Odds ratio |
| keywords[6].id | https://openalex.org/keywords/gastroenterology |
| keywords[6].score | 0.5219040513038635 |
| keywords[6].display_name | Gastroenterology |
| keywords[7].id | https://openalex.org/keywords/logistic-regression |
| keywords[7].score | 0.5009274482727051 |
| keywords[7].display_name | Logistic regression |
| keywords[8].id | https://openalex.org/keywords/chronic-constipation |
| keywords[8].score | 0.416654109954834 |
| keywords[8].display_name | Chronic constipation |
| keywords[9].id | https://openalex.org/keywords/physical-therapy |
| keywords[9].score | 0.337436318397522 |
| keywords[9].display_name | Physical therapy |
| language | en |
| locations[0].id | doi:10.1097/mcg.0000000000001245 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S69483707 |
| locations[0].source.issn | 0192-0790, 1539-2031 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0192-0790 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Journal of Clinical Gastroenterology |
| locations[0].source.host_organization | https://openalex.org/P4310315671 |
| locations[0].source.host_organization_name | Lippincott Williams & Wilkins |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310315671, https://openalex.org/P4310318547 |
| locations[0].source.host_organization_lineage_names | Lippincott Williams & Wilkins, Wolters Kluwer |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of Clinical Gastroenterology |
| locations[0].landing_page_url | https://doi.org/10.1097/mcg.0000000000001245 |
| locations[1].id | pmid:31361710 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of clinical gastroenterology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/31361710 |
| locations[2].id | pmh:oai:europepmc.org:5816769 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306400806 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | Europe PMC (PubMed Central) |
| locations[2].source.host_organization | https://openalex.org/I1303153112 |
| locations[2].source.host_organization_name | European Bioinformatics Institute |
| locations[2].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/6791496 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5112841278 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Douglas C.A. Taylor |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I169613989 |
| authorships[0].affiliations[0].raw_affiliation_string | Ironwood Pharmaceuticals Inc., Cambridge, MA |
| authorships[0].institutions[0].id | https://openalex.org/I169613989 |
| authorships[0].institutions[0].ror | https://ror.org/05v86fk30 |
| authorships[0].institutions[0].type | company |
| authorships[0].institutions[0].lineage | https://openalex.org/I169613989 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Ironwood Pharmaceuticals (United States) |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Douglas C.A. Taylor |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Ironwood Pharmaceuticals Inc., Cambridge, MA |
| authorships[1].author.id | https://openalex.org/A5078318374 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Jessica L. Abel |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210139498 |
| authorships[1].affiliations[0].raw_affiliation_string | Allergan plc, Madison, NJ |
| authorships[1].institutions[0].id | https://openalex.org/I4210139498 |
| authorships[1].institutions[0].ror | https://ror.org/03pfqk412 |
| authorships[1].institutions[0].type | company |
| authorships[1].institutions[0].lineage | https://openalex.org/I2948728702, https://openalex.org/I4210139498 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Allergan (United States) |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Jessica L. Abel |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Allergan plc, Madison, NJ |
| authorships[2].author.id | https://openalex.org/A5103116756 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-3263-4337 |
| authorships[2].author.display_name | Jalpa A. Doshi |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I79576946 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA |
| authorships[2].institutions[0].id | https://openalex.org/I79576946 |
| authorships[2].institutions[0].ror | https://ror.org/00b30xv10 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I79576946 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | University of Pennsylvania |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Jalpa A. Doshi |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA |
| authorships[3].author.id | https://openalex.org/A5002323212 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-3512-7231 |
| authorships[3].author.display_name | Carolyn Martin |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210124242 |
| authorships[3].affiliations[0].raw_affiliation_string | Optum, Eden Prairie, MN |
| authorships[3].institutions[0].id | https://openalex.org/I4210124242 |
| authorships[3].institutions[0].ror | https://ror.org/0370sjj75 |
| authorships[3].institutions[0].type | company |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210124242 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Optum (United States) |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Carolyn Martin |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Optum, Eden Prairie, MN |
| authorships[4].author.id | https://openalex.org/A5047986332 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Alyssa Goolsby Hunter |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210124242 |
| authorships[4].affiliations[0].raw_affiliation_string | Optum, Eden Prairie, MN |
| authorships[4].institutions[0].id | https://openalex.org/I4210124242 |
| authorships[4].institutions[0].ror | https://ror.org/0370sjj75 |
| authorships[4].institutions[0].type | company |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210124242 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | Optum (United States) |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Alyssa Goolsby Hunter |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Optum, Eden Prairie, MN |
| authorships[5].author.id | https://openalex.org/A5061209935 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Breanna Essoi |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210124242 |
| authorships[5].affiliations[0].raw_affiliation_string | Optum, Eden Prairie, MN |
| authorships[5].institutions[0].id | https://openalex.org/I4210124242 |
| authorships[5].institutions[0].ror | https://ror.org/0370sjj75 |
| authorships[5].institutions[0].type | company |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210124242 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Optum (United States) |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Breanna Essoi |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Optum, Eden Prairie, MN |
| authorships[6].author.id | https://openalex.org/A5108687162 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Stephanie Korrer |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210124242 |
| authorships[6].affiliations[0].raw_affiliation_string | Optum, Eden Prairie, MN |
| authorships[6].institutions[0].id | https://openalex.org/I4210124242 |
| authorships[6].institutions[0].ror | https://ror.org/0370sjj75 |
| authorships[6].institutions[0].type | company |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210124242 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | Optum (United States) |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Stephanie Korrer |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Optum, Eden Prairie, MN |
| authorships[7].author.id | https://openalex.org/A5063241288 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | David S. Reasner |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I169613989 |
| authorships[7].affiliations[0].raw_affiliation_string | Ironwood Pharmaceuticals Inc., Cambridge, MA |
| authorships[7].institutions[0].id | https://openalex.org/I169613989 |
| authorships[7].institutions[0].ror | https://ror.org/05v86fk30 |
| authorships[7].institutions[0].type | company |
| authorships[7].institutions[0].lineage | https://openalex.org/I169613989 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | Ironwood Pharmaceuticals (United States) |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | David S. Reasner |
| authorships[7].is_corresponding | True |
| authorships[7].raw_affiliation_strings | Ironwood Pharmaceuticals Inc., Cambridge, MA |
| authorships[8].author.id | https://openalex.org/A5044856750 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-6646-9595 |
| authorships[8].author.display_name | Robyn T. Carson |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210139498 |
| authorships[8].affiliations[0].raw_affiliation_string | Allergan plc, Madison, NJ |
| authorships[8].institutions[0].id | https://openalex.org/I4210139498 |
| authorships[8].institutions[0].ror | https://ror.org/03pfqk412 |
| authorships[8].institutions[0].type | company |
| authorships[8].institutions[0].lineage | https://openalex.org/I2948728702, https://openalex.org/I4210139498 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Allergan (United States) |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Robyn T. Carson |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Allergan plc, Madison, NJ |
| authorships[9].author.id | https://openalex.org/A5027136649 |
| authorships[9].author.orcid | https://orcid.org/0000-0002-4584-4026 |
| authorships[9].author.display_name | William D. Chey |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I27837315 |
| authorships[9].affiliations[0].raw_affiliation_string | Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI |
| authorships[9].institutions[0].id | https://openalex.org/I27837315 |
| authorships[9].institutions[0].ror | https://ror.org/00jmfr291 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I27837315 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | University of Michigan |
| authorships[9].author_position | last |
| authorships[9].raw_author_name | William D. Chey |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1097/mcg.0000000000001245 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2019-08-13T00:00:00 |
| display_name | The Impact of Stool Consistency on Bowel Movement Satisfaction in Patients With IBS-C or CIC Treated With Linaclotide or Other Medications |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10365 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2715 |
| primary_topic.subfield.display_name | Gastroenterology |
| primary_topic.display_name | Gastrointestinal motility and disorders |
| related_works | https://openalex.org/W4386038703, https://openalex.org/W1701249774, https://openalex.org/W2132693761, https://openalex.org/W2372816678, https://openalex.org/W2164738986, https://openalex.org/W3213001870, https://openalex.org/W54943504, https://openalex.org/W2131182385, https://openalex.org/W2808206140, https://openalex.org/W2328046556 |
| cited_by_count | 5 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 2 |
| counts_by_year[1].year | 2021 |
| counts_by_year[1].cited_by_count | 3 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1097/mcg.0000000000001245 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S69483707 |
| best_oa_location.source.issn | 0192-0790, 1539-2031 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0192-0790 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Journal of Clinical Gastroenterology |
| best_oa_location.source.host_organization | https://openalex.org/P4310315671 |
| best_oa_location.source.host_organization_name | Lippincott Williams & Wilkins |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310315671, https://openalex.org/P4310318547 |
| best_oa_location.source.host_organization_lineage_names | Lippincott Williams & Wilkins, Wolters Kluwer |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of Clinical Gastroenterology |
| best_oa_location.landing_page_url | https://doi.org/10.1097/mcg.0000000000001245 |
| primary_location.id | doi:10.1097/mcg.0000000000001245 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S69483707 |
| primary_location.source.issn | 0192-0790, 1539-2031 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0192-0790 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Journal of Clinical Gastroenterology |
| primary_location.source.host_organization | https://openalex.org/P4310315671 |
| primary_location.source.host_organization_name | Lippincott Williams & Wilkins |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310315671, https://openalex.org/P4310318547 |
| primary_location.source.host_organization_lineage_names | Lippincott Williams & Wilkins, Wolters Kluwer |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of Clinical Gastroenterology |
| primary_location.landing_page_url | https://doi.org/10.1097/mcg.0000000000001245 |
| publication_date | 2019-07-30 |
| publication_year | 2019 |
| referenced_works | https://openalex.org/W2594572760, https://openalex.org/W2146147731, https://openalex.org/W2009552042, https://openalex.org/W4211073917, https://openalex.org/W2039884246, https://openalex.org/W1921373566, https://openalex.org/W1997395361, https://openalex.org/W2079281535, https://openalex.org/W2031769161, https://openalex.org/W1987172422, https://openalex.org/W2117057134, https://openalex.org/W1913351632, https://openalex.org/W2034237219, https://openalex.org/W6768292422, https://openalex.org/W2145469804, https://openalex.org/W1966250447, https://openalex.org/W2978537175, https://openalex.org/W2085752173, https://openalex.org/W2038990291, https://openalex.org/W2606770995, https://openalex.org/W2574954804, https://openalex.org/W2977735081 |
| referenced_works_count | 22 |
| abstract_inverted_index.2 | 80 |
| abstract_inverted_index.P | 213 |
| abstract_inverted_index.a | 31, 88, 178 |
| abstract_inverted_index.24 | 109 |
| abstract_inverted_index.As | 36 |
| abstract_inverted_index.BM | 84, 140 |
| abstract_inverted_index.as | 115, 156, 183, 187, 204, 226, 230 |
| abstract_inverted_index.be | 241 |
| abstract_inverted_index.in | 17, 106 |
| abstract_inverted_index.of | 8, 46, 90, 113, 181, 200 |
| abstract_inverted_index.on | 11, 33 |
| abstract_inverted_index.or | 26, 117, 122, 126, 190, 228 |
| abstract_inverted_index.to | 4, 86, 222, 240 |
| abstract_inverted_index.BMs | 95, 114, 154, 182, 201, 224 |
| abstract_inverted_index.SEs | 148 |
| abstract_inverted_index.The | 132 |
| abstract_inverted_index.and | 55, 60, 69, 72, 111, 139, 159, 166 |
| abstract_inverted_index.for | 39, 96, 150 |
| abstract_inverted_index.may | 49 |
| abstract_inverted_index.new | 37 |
| abstract_inverted_index.nor | 130 |
| abstract_inverted_index.not | 249 |
| abstract_inverted_index.the | 6, 66, 107 |
| abstract_inverted_index.use | 194, 209 |
| abstract_inverted_index.was | 142, 195 |
| abstract_inverted_index.who | 173 |
| abstract_inverted_index.(BM) | 15 |
| abstract_inverted_index.1806 | 97 |
| abstract_inverted_index.2922 | 91 |
| abstract_inverted_index.Data | 62 |
| abstract_inverted_index.HoLS | 170 |
| abstract_inverted_index.LoWS | 129, 160, 188, 227 |
| abstract_inverted_index.This | 1 |
| abstract_inverted_index.for: | 103 |
| abstract_inverted_index.from | 65, 79 |
| abstract_inverted_index.hard | 121 |
| abstract_inverted_index.help | 50 |
| abstract_inverted_index.more | 163, 220, 238 |
| abstract_inverted_index.odds | 199 |
| abstract_inverted_index.past | 108 |
| abstract_inverted_index.than | 169 |
| abstract_inverted_index.use, | 138 |
| abstract_inverted_index.used | 105 |
| abstract_inverted_index.were | 63, 101, 161, 219, 237 |
| abstract_inverted_index.when | 185 |
| abstract_inverted_index.with | 19, 23, 30, 147, 197, 207 |
| abstract_inverted_index.(odds | 210 |
| abstract_inverted_index.1.23, | 212 |
| abstract_inverted_index.7-day | 82 |
| abstract_inverted_index.HoLS. | 233 |
| abstract_inverted_index.IBS-C | 70 |
| abstract_inverted_index.LoWS, | 246 |
| abstract_inverted_index.aimed | 3 |
| abstract_inverted_index.being | 202 |
| abstract_inverted_index.bowel | 13, 21 |
| abstract_inverted_index.daily | 83 |
| abstract_inverted_index.focus | 32 |
| abstract_inverted_index.hours | 110 |
| abstract_inverted_index.loose | 116 |
| abstract_inverted_index.lumpy | 123 |
| abstract_inverted_index.often | 164 |
| abstract_inverted_index.rated | 177 |
| abstract_inverted_index.stool | 9, 135 |
| abstract_inverted_index.study | 2, 78 |
| abstract_inverted_index.those | 244, 248 |
| abstract_inverted_index.using | 144 |
| abstract_inverted_index.(61.2% | 165 |
| abstract_inverted_index.26,524 | 94 |
| abstract_inverted_index.51.2%, | 167 |
| abstract_inverted_index.Binary | 99 |
| abstract_inverted_index.CONTOR | 217 |
| abstract_inverted_index.Goals: | 0 |
| abstract_inverted_index.HoLS). | 131 |
| abstract_inverted_index.become | 41 |
| abstract_inverted_index.create | 87 |
| abstract_inverted_index.higher | 198 |
| abstract_inverted_index.impact | 7 |
| abstract_inverted_index.inform | 56 |
| abstract_inverted_index.likely | 221, 239 |
| abstract_inverted_index.manage | 52 |
| abstract_inverted_index.ratio: | 211 |
| abstract_inverted_index.report | 223 |
| abstract_inverted_index.stools | 119, 124, 158 |
| abstract_inverted_index.taking | 175, 235, 250 |
| abstract_inverted_index.versus | 232, 247 |
| abstract_inverted_index.watery | 118 |
| abstract_inverted_index.(65.6%) | 189 |
| abstract_inverted_index.(HoLS), | 125 |
| abstract_inverted_index.(IBS-C) | 25 |
| abstract_inverted_index.(LoWS), | 120 |
| abstract_inverted_index.Chronic | 67 |
| abstract_inverted_index.between | 134 |
| abstract_inverted_index.chronic | 27 |
| abstract_inverted_index.created | 102 |
| abstract_inverted_index.dataset | 89 |
| abstract_inverted_index.derived | 64 |
| abstract_inverted_index.diaries | 85, 92 |
| abstract_inverted_index.effects | 48 |
| abstract_inverted_index.patient | 53 |
| abstract_inverted_index.similar | 179 |
| abstract_inverted_index.(19.4%). | 171 |
| abstract_inverted_index.(64.1%). | 192 |
| abstract_inverted_index.(CONTOR) | 77 |
| abstract_inverted_index.(neither | 128 |
| abstract_inverted_index.Methods: | 61 |
| abstract_inverted_index.Outcomes | 73 |
| abstract_inverted_index.Overall, | 216 |
| abstract_inverted_index.Platform | 76 |
| abstract_inverted_index.Research | 75 |
| abstract_inverted_index.Results: | 153 |
| abstract_inverted_index.analyzed | 143 |
| abstract_inverted_index.clinical | 57 |
| abstract_inverted_index.compared | 206 |
| abstract_inverted_index.logistic | 145 |
| abstract_inverted_index.movement | 14 |
| abstract_inverted_index.patients | 18 |
| abstract_inverted_index.repeated | 151 |
| abstract_inverted_index.reported | 174, 203 |
| abstract_inverted_index.syndrome | 22 |
| abstract_inverted_index.Materials | 59 |
| abstract_inverted_index.Treatment | 71 |
| abstract_inverted_index.corrected | 149 |
| abstract_inverted_index.described | 186 |
| abstract_inverted_index.irritable | 20 |
| abstract_inverted_index.reporting | 245 |
| abstract_inverted_index.treatment | 47 |
| abstract_inverted_index.variables | 100 |
| abstract_inverted_index.<0.05). | 214 |
| abstract_inverted_index.Real-world | 74 |
| abstract_inverted_index.associated | 196 |
| abstract_inverted_index.available, | 42 |
| abstract_inverted_index.classified | 225 |
| abstract_inverted_index.clinicians | 51 |
| abstract_inverted_index.idiopathic | 28 |
| abstract_inverted_index.medication | 137 |
| abstract_inverted_index.proportion | 180 |
| abstract_inverted_index.regression | 146 |
| abstract_inverted_index.satisfied, | 242 |
| abstract_inverted_index.Background: | 35 |
| abstract_inverted_index.Linaclotide | 193 |
| abstract_inverted_index.consistency | 10 |
| abstract_inverted_index.linaclotide | 176, 236 |
| abstract_inverted_index.medications | 38 |
| abstract_inverted_index.patients’ | 44 |
| abstract_inverted_index.perceptions | 45 |
| abstract_inverted_index.Conclusions: | 215 |
| abstract_inverted_index.Constipation | 68 |
| abstract_inverted_index.Participants | 172, 234 |
| abstract_inverted_index.characterize | 5 |
| abstract_inverted_index.consistency, | 136 |
| abstract_inverted_index.constipation | 24, 40 |
| abstract_inverted_index.expectations | 54 |
| abstract_inverted_index.intermediate | 127, 157, 191, 229 |
| abstract_inverted_index.linaclotide. | 34, 251 |
| abstract_inverted_index.participants | 218 |
| abstract_inverted_index.particularly | 243 |
| abstract_inverted_index.relationship | 133 |
| abstract_inverted_index.representing | 93 |
| abstract_inverted_index.satisfaction | 16, 141 |
| abstract_inverted_index.satisfactory | 162, 184, 205 |
| abstract_inverted_index.characterized | 155 |
| abstract_inverted_index.constipation, | 29 |
| abstract_inverted_index.medication(s) | 104 |
| abstract_inverted_index.observations. | 152 |
| abstract_inverted_index.participants. | 98 |
| abstract_inverted_index.respectively) | 168 |
| abstract_inverted_index.satisfactory, | 231 |
| abstract_inverted_index.understanding | 43 |
| abstract_inverted_index.categorization | 112 |
| abstract_inverted_index.nonlinaclotide | 208 |
| abstract_inverted_index.decision-making. | 58 |
| abstract_inverted_index.patient-reported | 12, 81 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 95 |
| corresponding_author_ids | https://openalex.org/A5112841278, https://openalex.org/A5063241288 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 10 |
| corresponding_institution_ids | https://openalex.org/I169613989 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/16 |
| sustainable_development_goals[0].score | 0.7099999785423279 |
| sustainable_development_goals[0].display_name | Peace, Justice and strong institutions |
| citation_normalized_percentile.value | 0.66685866 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |