The importance of curve severity, type and instrumentation strategy in the surgical correction of adolescent idiopathic scoliosis: an in silico clinical trial on 64 cases Article Swipe
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· 2021
· Open Access
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· DOI: https://doi.org/10.1038/s41598-021-81319-z
Adolescent idiopathic scoliosis is a three-dimensional deformity of the spine which is frequently corrected with the implantation of instrumentation with generally good or excellent clinical results; mechanical post-operative complications such as implant loosening and breakage are however relatively frequent. The rate of complications is associated with a lack of consensus about the surgical decision-making process; choices about the instrumentation length, the anchoring implants and the degree of correction are indeed mostly based on personal views and previous experience of the surgeon. In this work, we performed an in silico clinical trial on a large number of subjects in order to clarify which factors have the highest importance in determining the risk of complications by quantitatively analysing the mechanical stresses and loads in the instrumentation after the correction maneuvers. The results of the simulations highlighted the fundamental role of the curve severity, also in its three-dimensional aspect, and of the instrumentation strategy, whereas the length of the fixation had a lower importance.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1038/s41598-021-81319-z
- https://www.nature.com/articles/s41598-021-81319-z.pdf
- OA Status
- gold
- Cited By
- 9
- References
- 71
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3126070638
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3126070638Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1038/s41598-021-81319-zDigital Object Identifier
- Title
-
The importance of curve severity, type and instrumentation strategy in the surgical correction of adolescent idiopathic scoliosis: an in silico clinical trial on 64 casesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-01-19Full publication date if available
- Authors
-
Fabio Galbusera, Andrea Cina, Matteo Panico, Tito BassaniList of authors in order
- Landing page
-
https://doi.org/10.1038/s41598-021-81319-zPublisher landing page
- PDF URL
-
https://www.nature.com/articles/s41598-021-81319-z.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.nature.com/articles/s41598-021-81319-z.pdfDirect OA link when available
- Concepts
-
Instrumentation (computer programming), Idiopathic scoliosis, Deformity, Scoliosis, Medicine, Implant, Surgery, Computer science, Operating systemTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
9Total citation count in OpenAlex
- Citations by year (recent)
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2025: 4, 2024: 4, 2021: 1Per-year citation counts (last 5 years)
- References (count)
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71Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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