The need for open and FAIR data in top‐down proteomics Article Swipe
In recent years, there has been a tremendous evolution in the high‐throughput, tandem mass spectrometry‐based analysis of intact proteins, also known as top‐down proteomics (TDP). Both hardware and software have developed to the point that the technique has largely entered the mainstream, and large‐scale, ambitious, multi‐laboratory initiatives have started to make their appearance in the literature. For this, however, more convenient and robust data sharing and reuse will be required. Walzer et al. have created TopDownApp, a customisable, open platform for visualisation and analysis of TDP data, which they hope will be a step in this direction. As they point out, other benefits of such data sharing and interoperability would include reanalysis of published datasets, as well as the prospect of using large amounts of data to train machine learning algorithms. In time, this work could prove to be a valuable resource in the move towards a future of greater TDP data findability, accessibility, interoperability and reusability.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/pmic.202300354
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pmic.202300354
- OA Status
- hybrid
- Cited By
- 1
- References
- 28
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4389674566Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1002/pmic.202300354Digital Object Identifier
- Title
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The need for open and FAIR data in top‐down proteomicsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-12-13Full publication date if available
- Authors
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Frederik LermyteList of authors in order
- Landing page
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https://doi.org/10.1002/pmic.202300354Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pmic.202300354Direct link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pmic.202300354Direct OA link when available
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Interoperability, Computer science, Reuse, Reusability, Software, Resource (disambiguation), World Wide Web, Data science, Linked data, Data sharing, Software engineering, Semantic Web, Operating system, Engineering, Medicine, Computer network, Pathology, Alternative medicine, Waste managementTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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28Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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