Exploring foci of:
Frontiers in Pharmacology • Vol 15
The pharmacoepigenetic paradigm in cancer treatment
April 2024 • Belén Ocaña-Paredes, Sebastián Rivera-Orellana, David Ramírez, Juliana Montalvo-Guerrero, María Paula Freire, Samantha Espinoza-Ferrao, Adriana Altam…
Epigenetic modifications, characterized by changes in gene expression without altering the DNA sequence, play a crucial role in the development and progression of cancer by significantly influencing gene activity and cellular function. This insight has led to the development of a novel class of therapeutic agents, known as epigenetic drugs. These drugs, including histone deacetylase inhibitors, histone acetyltransferase inhibitors, histone methyltransferase inhibitors, and DNA methyltransferase inhibitors, aim to …
Epigenetics
Histone Deacetylase
Cancer
Medicine
Bioinformatics
Catechol-O-Methyltransferase
Biology
Histone
Pharmacology
Gene Expression
Internal Medicine